Non-Migraine Primary Headaches in Medicine: A Machine-Generated Overview of Current Research 3031208935, 9783031208935

Table of contents :
Preface
Contents
Chapter 1: Tension-Type Headache
1.1 Introduction
1.2 Machine-Generated Summaries
Public Health
The Global Prevalence of Headache: An Update, with Analysis of the Influences of Methodological Factors on Prevalence Estimates
Incidence, Prevalence and Disability Associated with Neurological Disorders in Italy Between 1990 and 2019: An Analysis Based on the Global Burden of Disease Study 2019
Burden of Tension-Type Headache in the Middle East and North Africa Region, 1990–2019
The Burden of Headache Disorders in the Eastern Mediterranean Region, 1990–2016: Findings from the Global Burden of Disease Study 2016
One-Quarter of Individuals with Weekly Headache Have Never Consulted a Medical Doctor: A Danish Nationwide Cross-Sectional Survey
A Prospective Real-World Study Exploring Associations Between Passively Collected Tracker Data and Headache Burden Among Individuals with Tension-Type Headache and Migraine
Prevalence and Burden of Headache in Children and Adolescents in Austria: A Nationwide Study in a Representative Sample of Pupils Aged 10–18 Years
Epidemiological and Clinical Characteristics of Primary Headaches in Adolescent Population: Is There a Relationship with the Way of Life?
The Epidemiology of Headache Disorders: A Face-to-Face Interview of Participants in HUNT4
Proposing a Measurement Model of REBT and Applying it to the Assessment of Well-Being and Happiness in Patients with Tension-Type Headaches
Mechanisms
Tension-Type Headache
Current Understanding of the Pathophysiology and Approach to Tension-Type Headache
Understanding the Interaction Between Clinical, Emotional and Psychophysical Outcomes Underlying Tension-Type Headache: A Network Analysis Approach
Brain Excitability in Tension-Type Headache: A Separate Entity from Migraine?
Pressure Pain Thresholds over the Cranio-Cervical Region in Headache: A Systematic Review and Meta-Analysis
Myofascial Trigger Points in Migraine and Tension-Type Headache
Comparison of Gray Matter Volume Between Migraine and “Strict-Criteria” Tension-Type Headache
Salivary Inflammatory Markers in Tension Type Headache and Migraine: The SalHead Cohort Study
The Association Between Serum Vitamin B12 Deficiency and Tension-Type Headache in Turkish Children
The Role of the Autonomic Nervous System in Headache: Biomarkers and Treatment
Diagnosis
Reference Programme: Diagnosis and Treatment of Headache Disorders and Facial Pain. Danish Headache Society, 3rd Edition, 2020
Validation of an Algorithm for Automated Classification of Migraine and Tension-Type Headache Attacks in an Electronic Headache Diary
Machine Learning-Based Automated Classification of Headache Disorders Using Patient-Reported Questionnaires
Primary Headaches During Lifespan
Co-occurrence of Pain Syndromes
Characteristics of Headache Disorders, According to ICHD-III in an Outpatient Headache Clinic in Sohag Governorate, Egypt
The Applicability Research of the Diagnostic Criteria for 6.7.2 Angiography Headache in the International Classification of Headache Disorders, 3rd Edition
Tension-Type Headache in the Emergency Department Diagnosis and Misdiagnosis: The TEDDi Study
Sleep and Tension-Type Headache
Migraine and Tension Headache Comorbidity with Hypothyroidism in Egypt
Quantitative Analysis of the Retinal Nerve Fiber Layer, Ganglion Cell Layer and Optic Disc Parameters by the Swept Source Optical Coherence Tomography in Patients with Migraine and Patients with Tension-Type Headache
Sensory Function in Headache: A Comparative Study Among Patients with Cluster Headache, Migraine, Tension-Type Headache, and Asymptomatic Subjects
Cognitive Performance in Patients with Chronic Tension-Type Headache and Its Relation to Neuroendocrine Hormones
Geographical Differences in Trigger Factors of Tension-Type Headaches and Migraines
Drug-Naïve Egyptian Females with Migraine Are More Prone to Sexual Dysfunction Than Those with Tension-Type Headache: A Cross-Sectional Comparative Study
Treatment
Aids to Management of Headache Disorders in Primary Care (2nd Edition)
Variables Associated with Use of Symptomatic Medication During a Headache Attack in Individuals with Tension-Type Headache: A European Study
Treatment of Tension-Type Headaches in Adolescents (14–15 Years Old): The Efficacy of Aminophenylbutyric Acid Hydrochloride
Efficacy and Feasibility of Behavioral Treatments for Migraine, Headache, and Pain in the Acute Care Setting
Manual Therapy and Quality of Life in People with Headache: Systematic Review and Meta-analysis of Randomized Controlled Trials
Manual Joint Mobilisation Techniques, Supervised Physical Activity, Psychological Treatment, Acupuncture and Patient Education for Patients with Tension-Type Headache. A Systematic Review and Meta-analysis
A Short Review of the Treatment of Headaches Using Osteopathic Manipulative Treatment
Effectiveness of Mulligan Manual Therapy over Exercise on Headache Frequency, Intensity and Disability for Patients with Migraine, Tension-Type Headache and Cervicogenic Headache: A Protocol of a Pragmatic Randomized Controlled Trial
Tension-Type Headache, Its Relation to Stress, and How to Relieve It by Cryotherapy Among Academic Students
Safety and Efficacy of Melatonin in Chronic Tension-Type Headache: A Post-Marketing Real-World Surveillance Program
The Best from East and West? Acupuncture and Medical Training Therapy as Monotherapies or in Combination for Adult Patients with Episodic and Chronic Tension-Type Headache: Study Protocol for a Randomized Controlled Trial
References
Chapter 2: Trigeminal Autonomic Cephalalgias
2.1 Introduction
2.2 Machine-Generated Summaries
Cluster Headache
Public Health
Chronic Cluster Headache Update and East–West Comparisons: Focusing on Clinical Features, Pathophysiology, and Management
Cluster Headache Is Still Lurking in the Shadows
Prevalence of Familial Cluster Headache: A Systematic Review and Meta-analysis
Cluster Headache: Clinical Characteristics and Opportunities to Enhance Quality of Life
Cluster Headache in Relation to Different Age Groups
Cluster Headache Impact Questionnaire (CHIQ)—A Short Measure of Cluster Headache Related Disability
The Economic and Personal Burden of Cluster Headache: A Controlled Cross-sectional Study
Direct and Indirect Costs of Cluster Headache: A Prospective Analysis in a Tertiary Level Headache Centre
Burden of Migraine in Finland: Multimorbidity and Phenotypic Disease Networks in Occupational Healthcare
Impact of Cluster Headache on Employment Status and Job Burden: A Prospective Cross-sectional Multicenter Study
Cluster Headache and the Comprehension Paradox
Mechanisms
Cluster Headache
Cluster Headache: Pathophysiology, Diagnosis and Treatment
Olfactory Dysfunction in Patients with Cluster Headache
The Role of Neurotransmitters and Neuromodulators in the Pathogenesis of Cluster Headache: A Review
Migraine and Cluster Headache Show Impaired Neurosteroids Patterns
Cluster Headache: Insights from Resting-State Functional Magnetic Resonance Imaging
Population-Based Analysis of Cluster Headache-Associated Genetic Polymorphisms
Analysis of HCRTR2, GNB3, and ADH4 Gene Polymorphisms in a Southeastern European Caucasian Cluster Headache Population
Genetic Association of HCRTR2, ADH4 and CLOCK Genes with Cluster Headache: A Chinese Population-Based Case-Control Study
VDR Gene Polymorphisms and Cluster Headache Susceptibility: Case–Control Study in a Southeastern European Caucasian Population
Implications for the Migraine SNP rs1835740 in a Swedish Cluster Headache Population
Clinical Symptoms of Androgen Deficiency in Men with Migraine or Cluster Headache: A Cross-sectional Cohort Study
Alterations of Thalamic Nuclei Volumes in Patients with Cluster Headache
Alterations of the Structural Covariance Network in the Hypothalamus of Patients with Cluster Headache
Changes in Grey Matter Volume and Functional Connectivity in Cluster Headache Versus Migraine
Diagnosis
Cluster Headache and TACs: State of the Art
Migraine and Cluster Headache—The Common Link
Systematic Literature Review on the Delays in the Diagnosis and Misdiagnosis of Cluster Headache
Exploring the Connection Between Sleep and Cluster Headache: A Narrative Review
Cluster Headache and Risk of Chronic Transformation
Clinical Features of Cluster Headache in Relation to Age of Onset: Results from a Retrospective Study of a Large Case Series
Clinical Features of Cluster Headache Without Cranial Autonomic Symptoms: Results from a Prospective Multicentre Study
Cluster Headache, Beyond the Pain: A Comparative Cross-sectional Study
Pre-attack and Pre-episode Symptoms in Cluster Headache: A Multicenter Cross-sectional Study of 327 Chinese Patients
Clinical Factors Influencing the Impact of Cluster Headache from a Prospective Multicenter Study
The Impact of Remission and Coexisting Migraine on Anxiety and Depression in Cluster Headache
Demoralization Predicts Suicidality in Patients with Cluster Headache
Associated Factors and Clinical Implication of Cutaneous Allodynia in Patients with Cluster Headache: A Prospective Multicentre Study
State and Trait Anger and Its Expression in Cluster Headache Compared with Migraine: A Cross-sectional Study
Behavioral and Psychological Aspects of Cluster Headache: An Overview
Treatment
Aids to Management of Headache Disorders in Primary Care (2nd Edition)
Recent Advances in the Management of Cluster Headache
Cluster Headache: A Review and Update in Treatment
Cluster Headache: Present and Future Therapy
Drug Treatment of Cluster Headache
Pharmacotherapy for Cluster Headache
Anti-CGRP in Cluster Headache Therapy
Cluster Headache Pathophysiology—Insights from Current and Emerging Treatments
Oxygen Treatment for Cluster Headache Attacks at Different Flow Rates: A Double-Blind, Randomized, Crossover Study
Safety and Efficacy of Percutaneous Pulsed Radiofrequency Treatment at the C1–C2 Level in Chronic Cluster Headache: A Retrospective Analysis of 21 Cases
A Retrospective Observation on 105 Patients with Chronic Cluster Headache Receiving Indomethacin
Galcanezumab Effectiveness on Comorbid Cluster Headache and Chronic Migraine: A Prospective Case Series
Different Doses of Galcanezumab Versus Placebo in Patients with Migraine and Cluster Headache: A Meta-analysis of Randomized Controlled Trials
Great Occipital Nerve Long-Acting Steroid Injections in Cluster Headache Therapy: An Observational Prospective Study
Non-invasive Vagus Nerve Stimulation for Treatment of Cluster Headache: Early UK Clinical Experience
Peripheral Nerve Stimulation for Chronic Pain: A Systematic Review of Effectiveness and Safety
High Dosage of Methylprednisolone in Cluster Headache
The Sensitivity to Change of the Cluster Headache Quality of Life Scale Assessed Before and After Deep Brain Stimulation of the Ventral Tegmental Area
Regional Cerebral Blood Flow as Predictor of Response to Occipital Nerve Block in Cluster Headache
Sphenopalatine Ganglion Stimulation for Cluster Headache, Results from a Large, Open-Label European Registry
Gamma Knife Radiosurgery for the Treatment of Cluster Headache: A Systematic Review
Other Trigeminal Autonomic Cephalalgias
Treatment of SUNCT/SUNA, Paroxysmal Hemicrania, and Hemicrania Continua: An Update Including Single-Arm Meta-analyses
Do Paroxysmal Hemicrania and Hemicrania Continua Represent Different Headaches? A Retrospective Study
Therapeutical Approaches to Paroxysmal Hemicrania, Hemicrania Continua and Short Lasting Unilateral Neuralgiform Headache Attacks: A Critical Appraisal
Hemicrania Continua: A Clinical Perspective on Diagnosis and Management
Hemicrania Continua Associated with an Unruptured Anterior Communicating Artery Aneurysm: First Case Report
First Case of Hemicrania Continua Responsive to Galcanezumab
Increase in CGRP Levels in a Case of Hemicrania Continua Normalizes After a Successful Response to Galcanezumab
SUNCT and SUNA: An Update and Review
Trigeminal Autonomic Cephalalgias Presenting in a Multidisciplinary Tertiary Orofacial Pain Clinic
CT-Guided Thermocoagulation of the Pterygopalatine Ganglion for Refractory Trigeminal Autonomic Cephalalgia
Treatment of Disabling Headache with Greater Occipital Nerve Injections in a Large Population of Childhood and Adolescent Patients: A Service Evaluation
References
Chapter 3: Other Non-migraine Primary Headache Disorders
3.1 Introduction
3.2 Machine-Generated Summaries
Other Primary Headaches. Cough Headache, Nummular Headache and Primary Exercise Headache: A Secondary Point of View
Exercise Headache: A Review
Primary Exercise Headache
Other Primary Headaches: Thunderclap-, Cough-, Exertional-, and Sexual Headache
Narrative Review: Headaches After Reversible Cerebral Vasoconstriction Syndrome
Thunderclap Headache in Children and Adolescents
Headache Attributed to Airplane Travel: A Review of Literature
Headache Attributed to Airplane Travel: Diagnosis, Pathophysiology, and Treatment—A Systematic Review
Diving Headache
Sherpas, Coca Leaves, and Planes: High Altitude and Airplane Headache Review with a Case of Post-LASIK Myopic Shift
Simulated Airplane Headache: A Proxy Towards Identification of Underlying Mechanisms
Headache and Barometric Pressure: A Narrative Review
Headache Attributed to Aeroplane Travel: The First Multicentric Survey in a Paediatric Population Affected by Primary Headaches
Primary Stabbing Headache
Nummular Headache: A Gender-Oriented Perspective on a Case Series from the RegistRare Network
Sleep Disorder-Related Headaches
New Daily Persistent Headache: A Diagnostic and Therapeutic Odyssey
Is New Daily Persistent Headache a Fallout of Somatization? An Observational Study
Cold Stimulus Headache
References

Citation preview

Non-Migraine Primary Headaches in Medicine A Machine-Generated Overview of Current Research Paolo Martelletti Editor

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Non-Migraine Primary Headaches in Medicine

Paolo Martelletti Editor

Non-Migraine Primary Headaches in Medicine A Machine-Generated Overview of Current Research

Editor Paolo Martelletti Department of Clinical and Molecular Medicine Sapienza University of Rome Rome, Italy

ISBN 978-3-031-20893-5    ISBN 978-3-031-20894-2 (eBook) https://doi.org/10.1007/978-3-031-20894-2 © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023 This work is subject to copyright. All rights are solely and exclusively licensed by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Preface

It is well established in all the international scientific literature that headache disorders are among the most prevalent and disabling conditions worldwide. The Global Burden of Diseases, gathering many important epidemiological studies, has confirmed the evidence of the high prevalence of tension-type headache, with a moderate level of caused disability, and the low prevalence of trigeminal autonomic cephalalgias which cause a very high disability, and the others non-migraine headache disorders for their potential risk caused by an incorrect diagnostic definition among primary and secondary forms. The help of Artificial Intelligence in finding, capturing and structuring what the most recent publications have highlighted in these non-migraine forms of primary headache is the fundamental passage of this book. It is aimed at all those who want to directly consult the original source of the literature to make informed clinical decisions reaching the exact publication needed. It is a new way of approaching the culture of headaches by skipping the interpretations and filters of the authors, providing everything that is necessary for a clinical decision that is informed from a diagnostic and therapeutic point of view. The correctness of the original information will allow both the headache expert and any clinician to reduce the diagnostic errors that can often lead to the risks of analgesics abuse and delays, sometimes even life-threatening. This volume, like the previous one on migraine, is dedicated to physicians facing in their daily clinical practice the non-migraine headache forms, to PhD students, to residents aiming to add value to the management of underestimated tension-type headache, to improve the immediate definition of trigeminal autonomic cephalalgias and other non-migraine primary headache disorders. Department of Clinical and Molecular Medicine

Paolo Martelletti

Sapienza University of Rome Rome, Italy

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Contents

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Tension-Type Headache��������������������������������������������������������������������������    1

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Trigeminal Autonomic Cephalalgias������������������������������������������������������  131

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Other Non-migraine Primary Headache Disorders������������������������������  321

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Chapter 1

Tension-Type Headache

1.1 Introduction Tension-type headache is the second most common cause of chronic pain in the Global Burden of Disease, affecting an estimated population of nearly 900 million new cases per year. The estimated prevalence of tension-type headache is enormous, with a very high variability from 10% up to 86% in young subjects. The global prevalence of the chronic form is equally important because it covers about two 3% of the global population. Despite such an important epidemiological economic impact, tension-type headache causes less disability than migraine. In terms of years of life lived with disabilities the comorbidities of tension-type headache are often similar to those of migraine such as anxiety, depression, sleep disturbances and other pain disorders including migraine itself. The physiopathology of the tension-­type headache is mainly based on genetic factors, myofascial mechanisms and chronicization mechanisms such as sensitization, therefore peripheral mechanisms and vascular factors are mostly unimportant. The central factors are important in the transformation from the episodic form to the chronic one. Unfortunately, the non-exact definition of the pathophysiology and the moderate burden impact and even a modest economic impact has left the tension-type headache, from a therapeutic point of view, still with old generation drugs, with no new compounds dedicated to this pathology for many decades. However, being a pathology with a great impact in the general population, it is useful to know the most important lines of research and any updates also in the field of complementary medicine that can guide the clinician in his/her daily practice.

© The Author(s), under exclusive license to Springer Nature Switzerland AG 2023 P. Martelletti (ed.), Non-Migraine Primary Headaches in Medicine, https://doi.org/10.1007/978-3-031-20894-2_1

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P. Martelletti

1.2 Machine-Generated Summaries Machine generated keywords: tth, migraine tth, tensiontype, tensiontype headache, burden, child, gbd, country, global, sleep, manual, muscle, adolescent, tension, tth migraine.

Public Health Machine generated keywords: gbd, burden, global, country, burden disease, burden headache, tth, adolescent, participant, migraine tth, epidemiological, global burden, live disability, million, health.

 he Global Prevalence of Headache: An Update, with Analysis T of the Influences of Methodological Factors on Prevalence Estimates DOI: https://doi.org/10.1186/s10194-­022-­01402-­2 Abstract-Summary According to the Global Burden of Disease (GBD) study, headache disorders are among the most prevalent and disabling conditions worldwide. GBD builds on epidemiological studies (published and unpublished) which are notable for wide variations in both their methodologies and their prevalence estimates. Our first aim was to update the documentation of headache epidemiological studies, summarizing global prevalence estimates for all headache, migraine, tension-­ type headache (TTH) and headache on ≥15 days/month (H15+), comparing these with GBD estimates and exploring time trends and geographical variations. Our second aim was to analyse how methodological factors influenced prevalence estimates. From 357 publications, the vast majority from high-income countries, the estimated global prevalence of active headache disorder was 52.0% (95% CI 48.9–55.4), of migraine 14.0% (12.9–15.2), of TTH 26.0% (22.7–29.5) and of H15+  4.6% (3.9–5.5). Methodological factors contributing to variation, were publication year, sample size, inclusion of probable diagnoses, sub-population sampling (e.g., of health-care personnel), sampling method (random or not), screening question (neutral, or qualified in severity or presumed cause) and scope of enquiry (headache disorders only or multiple other conditions).

1  Tension-Type Headache

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With these taken into account, migraine prevalence estimates increased over the years, while estimates for all headache types varied between world regions. The review confirms GBD in finding that headache disorders remain highly prevalent worldwide, and it identifies methodological factors explaining some of the large variation between study findings. These variations render uncertain both the increase in migraine prevalence estimates over time, and the geographical differences. Extended: Future studies should not assess prevalence alone but include data allowing TIS to be estimated, preferably among the various age and gender subgroups. Introduction Through the Global Burden of Disease (GBD) study, headache disorders are revealed as one of the major public-health concerns globally and in all countries and world regions [1]. For the various disorders it considers, GBD uses multiple data sources (epidemiological studies, health registers, official statistics, hospital data, etc.) to make best-informed estimates of prevalence and burden. They included criteria for judging the quality of studies from their reported methodology, and some adjustments to prevalence estimates were based upon these in the most detailed analysis of headache data, from GBD 2016 [1]. We reviewed all published studies of the prevalence and burden of headache [2]. We update that review, and the documentation of headache epidemiological studies, summarizing global prevalence estimates for headache, migraine, tension-type headache (TTH) and headache on ≥15 days/month (H15+), comparing these with GBD estimates and exploring time trends and geographical variations. Methods To geographical origin and publication year, we extracted data related to the quality criteria [3]: those describing the population of interest (the general population or a specified sub-population), sampling method (randomness and representativeness), size of sample, participating proportion, methods of data collection (access to and engagement with participants) and validation of diagnostic questions. For MLR analyses we dichotomized the quality measures [3] that were not interval or ordinal variables: population of interest (unselected [general] population of a country, community or tribe, or pupils of obligatory schools, versus selected subpopulations [e.g., university students, factory/workplace employees, minorities, etc.], or unstipulated [additionally, we registered whether selected subpopulations were health-care personnel such as medical students, hospital employees, neurologists, etc.]); sample representativeness of the population of interest (random sampling versus non-random sampling or failed attempt to secure randomness); access to and engagement with participants (face-to-face or telephone interview versus unsupervised questionnaire completion or unstipulated); validation of diagnostic questions (effort at validating versus none or unstipulated); application of ICHD criteria and distinction between definite and probable diagnoses versus not or unstipulated.

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Results Studies with mid-range age values below 10 or above 65  years reported lower migraine prevalences in both males and females, and studies with values below 10 years reported lower TTH prevalences in both genders. In studies estimating prevalences of an active headache disorder and of specific headache types, there were clear positive correlations between them: for headache with migraine (r = 0.46, p