Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy [2 ed.] 3031331559, 9783031331558

Table of contents :
Preface to the Second Edition
Contents
Contributors
Chapter 1: Introduction to Stereotactic Radiosurgery and Stereotactic Body Radiotherapy
Historical Foundations
Development of SRS and SBRT
Standard Fractionation Versus Hypofractionation
Summary
Nomenclature
References
Part I: Physics of Stereotactic Radiosurgery and Stereotactic Body Radiotherapy
Chapter 2: Physics of Stereotactic Radiosurgery and Stereotactic Body Radiotherapy
Pearls
Basic Principles
Treatment Platforms and Cross-Platform Comparisons
Quality Assurance and Patient Safety
References
Part II: Clinical Applications
Chapter 3: Intracranial Tumors
Pearls
Brain Metastases
Meningioma
Acoustic Neuroma
Paraganglioma
Pituitary Adenoma
Arteriovenous Malformation (AVM)
Neuropathic Facial Pain
Trigeminal Neuralgia
Cluster Headache
Sphenopalatine Neuralgia (Sluder’s Neuralgia)
Other
Treatment Indications
Workup
Radiosurgical Technique
Toxicities and Management
Recommended Follow-Up
Evidence
Brain Metastases
SRS Boost with WBRT
SRS Alone or With WBRT
SRS for >4 Brain Metastases
SRS Boost After Resection
Brainstem Lesions
Salvage After SRS
Meningioma
WHO Grade 1 Meningioma
WHO Grade 2 and 3 Meningioma
Skull Base
Ongoing
Acoustic Neuroma
Surgery vs. SRS
Hypofractionated Stereotactic RT vs. SRS
Proton Beam Radiosurgery
Paraganglioma
Hypofractionation
Surgery vs. SRS
Pituitary Adenoma
Hypofractionation
Hormone Control and Risk of Hypopituitarism
Vascular Malformations
Arteriovenous Malformation (AVM)
Staged AVM Treatment
AVM Treatment Versus Medical Management
Cavernous Malformation
Trigeminal Neuralgia
Primary Treatment
Retreatment
Pineal Tumors
Functional Disorders
Epilepsy
Parkinson Disease and Essential Tremor
References
Chapter 4: Spine
Pearls
Treatment indications
Workup
Radiosurgical Technique
Simulation and Treatment Planning
Dose Prescription
Dose Delivery
Toxicities and Management
Recommended Follow-Up
Evidence
Dose and Technique
SBRT Compared to Conventional EBRT
Postoperative SBRT
Spinal Cord Compression and Retreatment
Chordoma and Other Primary Tumors of the Spine and Skull Base
Vertebral Body Compression Fracture (VCF)
Pain Flare
Late Toxicity
References
Chapter 5: Head and Neck
Pearls
Workup
Treatment Indications
Radiosurgical Technique
Simulation and Treatment Planning
Dose Prescription
Dose Limitations
Dose Delivery
Toxicities and Management
Recommended Follow-Up
Evidence
Boost/Recurrence for Nasopharyngeal Carcinoma
Boost for Oropharyngeal Carcinoma
Postoperative
Laryngeal Carcinoma
Locoregionally Recurrent Head and Neck Cancer (Re-irradiation)
SBRT with Concurrent Systemic Therapy
SBRT for Elderly or Medically Unfit
References
Chapter 6: Lung
Pearls
Workup
Treatment Indications
Radiosurgical Technique
Simulation and Treatment Planning
Dose Prescription
Dose Limitations
Dose Delivery
Toxicities and Management
Recommended Follow-Up
Evidence
SBRT vs. Conventional Fractionation
SBRT in Medically Operable Patients
Pre-op SBRT
SBRT Fractionation Comparisons
SBRT for Central and Ultracentral Tumors
SBRT for Large Tumors >5 cm
SBRT for Re-irradiation
SBRT for Oligometastases
Technique
Dose Prescription
Treatment Planning
Motion Management
Follow-Up
References
Chapter 7: Digestive System
Introduction
Pearls
Pancreatic SBRT
Liver SBRT
Workup
Pancreatic Cancer
Hepatocellular Carcinoma (HCC)
Intrahepatic Cholangiocarcinoma (ICC)
Treatment Indications
SBRT vs. Other Liver-Directed Locoregional Therapies
Radiosurgical Technique
Simulation and Field Design
Dose Prescription
Pancreatic Cancer
HCC
ICC
Liver Metastasis
Treatment Delivery
Pancreatic SBRT
Liver SBRT
Toxicities and Management
Pancreatic SBRT
Liver SBRT
Recommended Follow-Up
Evidence
Pancreatic SBRT
Liver SBRT
Selected Ongoing Studies
Pancreatic SBRT
Liver SBRT
References
Chapter 8: Genitourinary Sites
SBRT for Clinically Localized Prostate Cancer
Checklist
Indications and Workup
Simulation
Contouring, Treatment Planning, and Image Guidance
Follow-Up
Evidence
SBRT Monotherapy
SBRT Boost
SBRT for Prostate Cancer: Oligometastasis-Directed Therapy
Oligometastatic Prostate Cancer
Evidence
SBRT for Renal and Adrenal Tumors
SBRT for Renal Cell Carcinoma (RCC)
Evidence
SBRT for Adrenal Gland Metastases
Evidence
References
Chapter 9: Gynecologic Sites
Pearls
Treatment Indications
Workup and Recommended Imaging
Radiosurgical Technique
Simulation and Treatment Planning
Dose Prescription
Dose Limitations
Dose Delivery
Toxicities and Management
Recommended Follow-Up
Evidence
SBRT for Oligometastases or as Re-irradiation for Recurrent Tumors
SBRT Boost in Initial Definitive Radiotherapy
References
Chapter 10: Soft Tissue Sarcoma
Pearls
Workup and Recommended Imaging
Treatment Indications
Radiosurgical Technique
Simulation and Treatment Planning
Dose Prescription
Toxicities and Management
Recommended Follow-Up
Evidence
Primary STS
Preoperative Radiation
Postoperative Radiation
Metastatic STS
Surgical or Radiofrequency Ablation
Radiotherapy for Metastatic Disease
SBRT for Lung Metastases
SBRT for Spine Metastases
SBRT for Liver Metastases
SRS for Brain Metastases
References
Chapter 11: Extracranial Oligometastases
Pearls
Treatment Indications
Workup
Radiosurgical Technique
Toxicities and Management
Recommended Follow-Up
Evidence
Prospective Trials
Meta-analyses
References
Appendix A: Dose-Volume Criteria
References
Index

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