Eradicating Heart Disease 0963876805

474 32 31MB

English Pages [212] Year 1997

Report DMCA / Copyright

DOWNLOAD FILE

Polecaj historie

Eradicating Heart Disease
 0963876805

Citation preview

THE MOST IMPORTANT BOOK OF YOUR

LIFE

ERADICATING HEART DISEASE MATTHIAS RATH, M.D.

Heart attacks and strokes are not diseases they are caused by vitamin deficiencies.

America's number one killers can be prevented by an optimum intake of essential nutrients. This book

shows you how.

ERADICATING HEART DISEASE MATTHIAS RATH, M.D.

Published by Health

Now

387 Ivy Street

San Francisco, CA 94102

You can purchase

this

book

at

USA

your bookstore.

from Health Now. your health food store or directly 1-800-624-2442 calling by

"An ounce of prevention

is

worth a pound of cure." President

Bill

Care address

Copyright

©1993

Clinton

in

to the U.S.

his Health

Congress.

by Matthias Rath, M.D.

All rights reserved. No part of this book may be transmitted in any form or by any means, electronic or mechnical, including photocopying, recording, or by any information storage and retrieval system, without written permission of the publisher.

ISBN 0-9638768-0-5

THE NUTRITIONAL DEFICIENCY THAT DOES NOT MAKE US HUNGRY

Vitamin deficiencies that cause heart attacks, strokes and other cardiovascular diseases do not give us warning signs. Unlike regular hunger, we don't feel stomach pain or any other alarm sign. The first signs that our body cells starve from vitamin deficiency are the outbreak of diseases. These diseases develop primarily in those organs which suffer most from nutritional deficiencies: the heart and the blood vessels.

"New thoughts and new

truths

go through three stages. First they are opposed. Then, finally they are

ridiculed. Next they are violently accepted as being self-evident."

Arthur

May this book help to make self-evident to optimum cardiovascular health.

to

all

that

Schopenhauer

vitamins are keys

Digitized by the Internet Archive in

2011

http://www.archive.org/details/eradicatingheartOOrath

HEART DISEASE THE EPIDEMIC OF THE 20TH CENTURY CAN BE ERADICATED -

Cardiovascular disease is the number one killer in the United States and many other countries. Every year, millions of people die from heart attacks and strokes, and millions more are left disabled. Heart disease has become an epidemic disease. Like all epidemics, heart disease is caused by one or only a few factors which have now been identified.

A hundred years ago, Louis

Pasteur, Robert Koch, and other brilliant discovered bacteria as the cause of infectious diseases. This led to the eradication of many infectious diseases and saved millions of lives. Now a medical discovery has been made that can lead to the eradication of heart attacks, strokes, and other forms of cardiovascular diseases. scientists,

recent years an

During

increasing

number

of

studies

indicated

the

Now.

vitamins in relation to cardiovascular breakthrough was made documenting that vitamin deficiency is in fact the primary cause of heart attacks, strokes. Most importantly, on the basis and other cardiovascular diseases. of these discoveries, we can now prevent cardiovascular diseases My discoveries by an optimum intake of nutritional supplements. benefits

disease.

of

finally,

a scientific

which

led

to

this

scientific

book. These discoveries

will

breakthrough are summarized in this have a direct impact on your personal

health and on the health of millions of people.

I

hope

that

personally to

recommendations of this book will help you achieve and maintain optimum cardiovascular health. the

I

TABLE OF CONTENTS PAGE INTRODUCTION Heart disease

is

a worldwide epidemic

8

The

heart disease epidemic

The

health care costs for cardiovascular diseases are skyrocketing

in

the United States

10 11

Most cardiovascular diseases are vitamin deficiencies

A

regimen

daily nutritional

for

12

optimum cardiovascular health

Testimonials: striking evidence

SECTION

animals don't get heart attacks

How

vitamin

C

-

the clinical evidence

22

your heart ten times greater than cholesterol

23

you have heard about cholesterol

The

reversal of existing cardiovascular diseases without surgery

How

-

24

but not about lipoprotein(a)

25

to start protecting your blood vessels and your heart

How you can

improve the performance

of

26

27

your heart

you can protect your blood vessels from free radical damage

SECTION

4

20

Why

When

1

19

prevents heart attacks and strokes

Vitamins prevent heart disease risk for

3

THE KEYS TO CARDIOVASCULAR HEALTH

A:

Why

A new

1

28

THE NATURE OF CARDIOVASCULAR DISEASE

B:

How

the blood circulation works

31

How

the heart

32

How

the heart works

How

the heart

Why

the coronary arteries are the most stressed arteries of the

How

a heart attack occurs

Mow

a stroke occurs

37

How

atherosclerotic deposits develop

38

How

lipoprotein(a)

is built

is

33

34

nourished

forms deposits

human body

35

36

in

40

the blood vessel wall

Impaired waste collection from the blood vessel wall increases deposits

41

What

42

is

lipoprotein(a)

Lipoprotein(a)

is

the greatest risk factor for cardiovascular disease today

You should know your Lipoprotein(a),

lipoprotein(a) blood levels

and LDL-cholesterol

-

how

to interpret

44

45 your personal

risk

46

Risk for lipoprotein(a) deposits increases with high lipoprotem(a) blood levels

48

Extent of atherosclerotic lesions increase with lipoprotem(a) deposited

49

The

lipoprotein(a)

Blood vessels Vitamin

C

vitamin

-

connection

50

the key

stability is

deficiency

C

51

the primary cause of cardiovascular disease

is

-

Early clinical evidence

-

Further evidence

-

The

53

-

54

-

-

proof

55

Heart attacks, strokes, and peripheral vascular diseases

The

pipeline

60

Essential nutrients can prevent

SECTION

59

phenomenon

C:

and reverse cardiovascular diseases

HOW TO PREVENT CARDIOVASCULAR

61

DISEASE

WITH NUTRITIONAL SUPPLEMENTS Vitamin

C

Vitamin

C adds

cuts heart disease rate

USA: more

years to your

vitamin

C

-

65

in half

66

life

67

less heart disease

Largest study ever conducted on vitamin

C and

heart disease prevention

Protecting your blood vessel wall against free radical

damage

68 70

Antioxidant vitamins reduce the risk for cardiovascular diseases

71

Europe: more vitamins

72

SECTION

D:

-

less heart disease

HOW TO REVERSE

EXISTING CARDIOVASCULAR

DISEASE WITH NUTRITIONAL SUPPLEMENTS Dietary vitamin

Deposits

in

C supplementation

reverses atherosclerotic deposits

77

coronary arteries lead to angina pectoris

Reversing heart disease and decreasing angina pectoris Nutritional

recommendations

to reverse heart

76

78

79

disease

Reversing heart disease within weeks: the proof

80

How

83

nutritional

supplements reverse existing atherosclerotic deposits

Vitamins reverse atherosclerotic deposits by increasing

A

teflon-like layer for

A

medical breakthrough from the laboratory bench

Lysine, proline

and vitamin C can

nutritional

excellence

in

health care"

84

85 87

halt the "atherosclerotic

Heart attacks and strokes can be eradicated call for

levels

your blood vessel walls

Reversing cardiovascular diseases with

"A

HDL

tumor"

supplements

89 90 91

92

1

SECTION

HOW TO NEUTRALIZE

E:

RISK FACTORS FOR

CARDIOVASCULAR DISEASE WITH NUTRITIONAL

SUPPLEMENTS Risk factors for heart disease are repair factors for blood vessel walls

Vitamin

C

95

lowers lipoprotein(a) blood levels

97

Vitamin B3 (nicotinic acid) lowers lipoprotein(a) blood levels

98

Vitamin

C decreases

Vitamin

C

lowers high cholesterol blood levels

100

Vitamin

C

lowers triglyceride levels

101

Vitamin

C

increases low blood levels of

high blood levels of cholesterol and triglycerides

HDL

(good cholesterol)

Other vitamins and essential nutrients normalizing blood Cardiovascular disease

How

diabetes can occur anywhere

in

cardiovascular disease develops

Vitamin

C

fat levels

in

diabetic patients

lowers blood sugar levels, insulin requirement

The higher

the vitamin

C

in

the diet

-

the lower the requirement for insulin

Testimonial from a diabetic patient following

my recommendations

Diabetic diseases can be eradicated

ways

Different

How

vitamin

Vitamin

C

in

which vitamin

SECTION

C reduces

the cardiovascular risk

02

103

104 105 107

108 109

1 1

112

the cardiovascular risk from external risk factors

HOW TO

F:

1

110

lowers high blood pressure

C decreases

99

114

EFFECTIVELY TREAT OTHER HEART

CONDITIONS WITH NUTRITIONAL SUPPLEMENTS What are

How

to

the

consequences

improve the quality

of

of

120

a heart attack

life

after a heart attack

122

What

is

What

are the main problems after coronary bypass surgery

How

to

What

How

is

to

a coronary artery bypass

improve quality

of

life

after

coronary bypass surgery

What causes

after angioplasty

How

127

1

29

heart failure epidemic

Heart failure patients have a short

The

124

128

heart failure

Heart failure causes impaired blood pumping

The

123

125

coronary angioplasty

improve the success rate

121

fatal

consequences

of

life

expectancy

incomplete treatment

of heart failure

vitamins can interrupt the vicious cycle of heart failure

Cardiomyopathies are primarily caused by vitamin deficiency

Coenzyme Q10

benefits patients with heart failure

132

135

136

IV

-

Coenzyme Q10 prolongs Less carnitine

the

life

of patients with heart

the heart muscle cells

in

-

-

muscle disease

more severe heart

138

139

failure

Carnitine benefits patients with heart failure

140

Testimonials from patients with heart failure

141

Heart failure can be eradicated

143

What causes

144

irregular heartbeat

The basic treatment

of irregular heartbeat

145

Magnesium reduces

irregular heartbeat

146

Carnitine reduces irregular heartbeat

147

Testimonials from arrhythmia patients

148

Arrhythmias can be eradicated

150

How

151

you can

live

longer and stay healthy

Other cardiovascular health recommendations

SECTION How

G:

152

ERADICATING HEART DISEASE

our ancestors

lost

the ability to manufacture vitamin

During the Ice Ages scurvy

was

Scorbutic blood loss

Repair molecules

became

C

155

the greatest threat to survival

1

the main cause of death during the Ice

became

matters of

life

and death during the

Ages

Ice

Ages

Today's cardiovascular diseases originated during the Ice Ages Defusing inherited time

Many

other diseases

bombs

may now

in

Why

164 in

your body

stop this unnecessary death

169

170

toll

persona! recommendations for you

171

172

"Call for excellence in health care"

Open

letter to

A

response from the White House

first

President

Open response to the Advocacy Scientific

for

a

new

Bill

letter

era

in

Clinton, Vice-President Al

from

Gore and

Hillary Clinton

medicine

-

a personal chronology

and medical discoveries made by the author

References

166 168

sight

people continue to die from preventable diseases

How we can My

is in

158

161

also be cured

eradication of heart disease

157

160

our bodies

Your cardiovascular health depends on an optimum vitamin pool

The

56

Hillary Clinton

1

73

1

75

1

76

177

179 180

INTRODUCTION

How You Can

Benefit Immediately

From

Reading This Book

The Scope

of the Heart

Disease Epidemic

HOW YOU CAN FROM READING •

This book

It

is

It

contains

It

It

It

is

handbook

a

for

BENEFIT

BOOK

THIS

optimum cardiovascular

an educational book about the number one

many illustrations and pictures how your body functions during

killer in

for better

health.

America.

understanding.

health and during disease. summarizes the most important heart disease studies and the benefits of gives my personal recommendations for optimum cardiovascular health.

explains

vitamins.

Most importantly, it shares with you the astonishing health improvements from who have already been following the health recommendations of this book.

patients

You can improve your They are

deficiency diseases.

Heart attacks and strokes are vitamin

health. essentially

unknown

those species that manufacture optimum amounts of

which vitamins

to take

and

in

in

the animal world, especially

their

own

vitamin C.

If

in

you know

what amounts, you can prevent heart attacks, strokes,

and many other diseases. This book gives

first

hand answers

to

your most important

questions about heart diseases.



You will obtain the latest scientific information on How to prevent heart attacks How to prevent strokes How to fight angina pectoris, the chest pain from heart disease How to reduce the clogging of blood vessels after bypass surgery How to reduce high cholesterol levels How to alleviate the risk from lipoprotein-a, a newly identified risk factor for heart

disease

-

ten times greater than cholesterol

How to prevent blindness and kidney failure in diabetic patients How to lower high blood pressure How to fight heart diseases caused by stress, smoking and other The answers

to

these and other important questions

source of information

for the rest of

your

will

make

this

factors

book an invaluable

life.

You can optimize your health with safe

nutritional

supplements.

Vitamins, minerals, and other essential nutritional supplements are products of nature.

These compounds have

Nutritional for

effectively maintained health over millions of years.

supplements can help your body function better without increasing the

undesirable side effects.

risk



You could Increase your

as the walls

of

its

life

expectancy.

blood vessels. You

system, the largest organ

of the

human

an important goal

learn

will

body.

of the

blood vessels

This

book describes how you can prevent

healthier

is

in

The human body

how

to protect

Maintaining the

is

as young

your blood vessel

stability

and

flexibility

preventing premature aging of your body. early aging

and achieve a longer and

life.

• You can save money. Nutritional supplements are not only a very effective way to maintain your health, but also a very economical way. The daily amount of

nutritional

supplements necessary

to

prevent heart attacks and strokes costs only a

few dimes.

You can take

own health. This book does not optimum cardiovascular health, also shares with you the proof: the amazing health improvements of people who have been following the recommendations of this book. This book has been written to encourage you to take better charge of your

only give you advice for

better charge of your



own

it

health.

You can help your loved ones. This book contains information important to human being. Share this information with your family, your friends, your

every

The medical discoveries reported in this book are also important for their and their lives. Your loved ones will be grateful to you for passing on this

neighbors. health

information.



You can make

all

the difference. The

primary cause of heart attacks and strokes

first

report that vitamin deficiency

was published more than 50 years

Ignoring this report cost the lives of over half a billion people,

more than

mankind together. This unnecessary dying can be stopped, with your

in all

is

a

ago.

wars

of

help.

Food and Drug Administration is trying to limit the free access of amino acids and other nutritional supplements by making them prescription drugs. By doing so. this federal agency does not serve the interests of millions of Americans who would be deprived of an effective, safe, and Presently, the U.S.

the American people to vitamins,

affordable

way

to

improve

their health.

You can become an advocate for an effective, safe, and affordable health care for yourself and also for the benefit of your loved ones. This book gives you important arguments based on the latest scientific discoveries and clinical studies. Talk about this book within your community, to your local newspaper. Ask them to report about these important discoveries. Contact your political representatives. You can make the difference.

THE PROBLEM:

HEART DISEASE

IS

A WORLDWIDE EPIDEMIC

According to the World Health Organization More

Than 12

Million

People Die Every Year From

Cardiovascular Diseases.



In

Most Countries Every Second

by Cardiovascular Diseases

-

Both

Death in

is

Caused

Men and

Women

The

table on the next

page shows you the world-wide scope

of the heart

epidemic. The data were provided by the World Health Organization

Note that some European countries have changed names

In this

in

table the death rates from cardiovascular diseases

(WHO)

disease in

1987.

the meantime.

in

men

industrialized nations. For each country the closed rectangles

are

show

shown

for

32

the death rates

from cardiovascular diseases per 100,000 inhabitants. The open rectangles show the

death rates from

all

other causes,

in

a given country, taken together.

In

most

countries listed cardiovascular diseases are responsible for about every second

death.

Death Rates Per 100.000 Population

1000

1500

2000

Hungary Soviet

Union(

Czechoslov.(*) Poland Bulgaria

Rumania Scotland. No. Ireland Finland

Yugoslavian Ireland

Germany DR(*

New Zealand England/Wales

Norway Austria

Denmark

USA Germany FR(* Sweden

Death Rate From Cardiovascular

Israel

Diseases

Australia

Belgium Netherlands

Canada

Other Causes

All

of

Death Together

Portugal Italy

Data

All

WHO.

1987

Greece Spain

Switzerland France

Japan

*)

Name

of

Country

Changed Since

10

THE PROBLEM: THE HEART DISEASE EPIDEMIC IN THE UNITED STATES





More Than 7 Millions Americans Have Been Diagnosed With Coronary Heart Disease Presently,

Every Year 1.5 Million Americans

Will Suffer

a Heart Attack.



300,000 of These Patients Will Die Suddenly

-

Before They Can Reach a Hospital or Can Receive

Medical



Attention.

Millions of

Forms

Americans Suffer Presently From Other

of Cardiovascular

Diseases and Related

Diseases:



29 Million Americans Suffer From High Blood Pressure.



8 Million Americans Suffer

From

Irregular Heartbeat



2.5 Million

Americans Suffer From

Cerebrovascular Diseases (Atherosclerotic Deposits

in

the Brain Arteries).

11

THE PROBLEM:

THE HEALTH CARE COSTS FOR CARDIOVASCULAR DISEASES ARE SKYROCKETING

100 Billion Dollars Are Spent

on the Treatment Every Year

-

in

the

of Cardiovascular

United States

Diseases

$ 200,000 Every Minute.

The Costs

for Coronary Bypass Operations the Most Frequent Surgical Treatment of Heart Disease

Amount

the United States

in

to

$10 Billion

Every Year. Survivors of Heart Attacks and Strokes Frequently

Become Disabled and

Live

Costs for Nursing Homes

Amount

to

Over $60

Health care costs are skyrocketing

Exploding health care cost have

The

direct

and

greatest burden

growth

-

in

Nursing Homes. The

in

in

the United States

Every Year.

Billion

the United States and

become

in

many

indirect costs for the treatment of cardiovascular

among

other countries.

the greatest threat to economic recovery.

the health care expenses.

diseases

Everyone interested

in

is

the

economic

the government, large and small businesses as well as health maintenance

organizations and health insurance companies

promising

new ways

to control health

-

must have an immediate

interest in

care costs.

This book presents a fascinating solution to the heart disease epidemic. Many epidemics have occurred throughout history. All these epidemics were caused by one or only a

few

factors. Infectious diseases, for

example, are caused by a bacterium or

a virus. Cardiovascular diseases are no exception: they are caused by vitamin deficiencies. That's what this book is all about. Let us now take a closer look at this breathtaking solution to the

number one

health challenge.

12

THE SOLUTION

MOST CARDIOVASCULAR DISEASES ARE VITAMIN DEFICIENCIES

Vitamin Deficiency

in

Coronary Arteries -> Clogging

-> Heart Attack

Vitamin Deficiency

in

'Electrical' Cells

-> Irregular Heartbeat

(Arrhythmia)

Vitamin Deficiency

in

Heart Muscle Cells ->

Weak

Blood Pumping

-> Shortness of Breath ->

How can organ

Edema

vitamin deficiencies cause cardiovascular disease?

cardiovascular system.

of the

throughout the

human

Thus, the heart

is

Its

main function

The

heart

human body and

which make up the heart. These

is



vitamin deficient they

Vitamin deficiencies

the central

cells

the organ undergoing the

a particular challenge to the

need an optimum supply

vitamins and other essential cofactors for their proper functioning.

become

is

the pumping of blood

body, 70 times per minute, more than 100,000 times per day.

the busiest organ of the

greatest mechanical stress. This mechanical stress millions of cells

is

in

fail

and

different

forms

of heart

If

of

the heart cells

diseases develop.

the blood vessels of the heart (coronary arteries) lead to the

clogging of these arteries and to heart attack. •

Vitamin deficiencies

in

the electrical cells of the heart lead to irregular heartbeat

(arrhythmia). •

Vitamin deficiencies

in

the heart muscle cells lead to impaired blood pumping, to

shortness of breath and to edema.

Optimum

intake of vitamins

helps prevent cardiovascular diseases.

13

THE SOLUTION: A DAILY NUTRITIONAL REGIMEN FOR OPTIMUM CARDIOVASCULAR HEALTH Below are my key recommendations supplement plan based on the latest nutritional •







scientific discoveries in

cardiovascular and

medicine.

These recommendations contain all the ingredients you will read about in These recommendations are being followed by several thousand people. Health improvements of people following these recommendations are

documented •

cardiovascular health: a daily nutritional

for

in this

this

book.

book.

These recommendations are made for everybody who wants to maintain optimum health of the heart and blood vessels. These recommendations are made particularly for those among my readers with existing heart disease.

My

daily cardiovascular health

recommendations

are based on the following nutrients:

Vitamin C

(Blood Vessel

Stability,

Deposit

Removal

Cell Fuel. Antioxidant)

(Deposit Removal. Antioxidant)

Vitamin E

(Antioxidant)

Beta Carotene

(Blood Vessel Teflon. Atherosclerotic Deposit Removal)

L-Proline

(Blood Vessel Teflon. Atherosclerotic Deposit Removal. Cell Fuel)

L-Lysine L-Carnitine

(Cell Fuel)

Coenzyme Q10

(Cell Fuel)

Vitamin B-1

(Cell Fuel) (Cell Fuel)

Vitamin B-2

(Cholesterol-Lowering. Cell Fuel)

Vitamin B-3 (Niacin) Vitamin B-3 (Niacinamide)

(Cell Fuel) (Cell Fuel)

Vitamin B-5 (Pantothenate) Vitamin B-6 Vitamin B-12 Folic Acid Vitamin D

(Cell Fuel)

(Blood Cell Factor. Cell Fuel)

(Blood Cell Factor. Cell Fuel)

(Bones) (Cell

Biotin

Fuel)

Calcium, Magnesium, Zinc, Manganese, Copper, Selenium, Chromium, Molybdenum (Minerals And Trace Elements Are Required For Many Cell Functions).

At the end of this book you

will find

detailed information

about these recommendations.

14

EVIDENCE

STRIKING The for

following testimonials are from patients

who have

followed

my recommendations

cardiovascular health. Their health improvements are striking evidence for the

value of vitamins and essential nutrients

the treatment of heart disease.

in

severe heart muscle weakness. G.P. is an his life was changed by a sudden occurrence of cardiac failure, a weakness of the heart muscle leading to a decreased pumping function and to an enlargement of the heart chambers. The patient could no longer fully meet his professional requirements and had to give up his sport activities. G.P.

patient

a

is

entrepreneur

in

with

a

Three years ago

his fifties.

On some days he

felt

so weak that he couldn't climb

drinking glass with both hands.

Because

of the

and he had

to hold his

weak pumping

function of

stairs

continued

and the unfavorable prognosis of this disease, his cardiologist recommended a heart transplant operation: "I recommend you get a new heart."

the

heart

At this point the patient started to follow

my

His physical strength improved gradually. obligations on a regular basis

months

his cardiologist

and was able

noted a decrease

cardiovascular health recommendations.

Soon he could again to

in

fulfill

undertake daily bicycle

his professional rides. After

the echocardiography examination, another sign of a recovering heart muscle.

month

later,

the patient

was

two

size of the previously enlarged heart

able to undertake a business

trip

in

One

abroad by plane, and he

could attend to his business affairs without any physical limitations.

is a 76 year old patient with coronary heart disease. For several months he had been suffering from shortness of breath and chest pain (angina pectoris) which occurred during regular walking. He was hospitalized in January 1993,

H.K.

after suffering

was taken

a life-threatening angina pectoris attack.

to the intensive

irregular heart beat.

When

During the hospital stay, he

care unit because of cardiac failure and a severely

The symptoms continued throughout the ten-week

he was dismissed from the hospital, the symptoms had only

hospital stay.

slightly

improved

despite a combination of multiple cardiac drugs. Chest pain, shortness of breath and irregular heartbeat continued to

physician

who

first

stairs.

The

had treated H.K. during his hospital stay gave him a very unfavorable

prognosis with respect to

The

occur after only a few steps when climbing

week

after

life

expectancy.

leaving the

hospital

the

patient

started

to

follow

my

cardiovascular health recommendations. His general as well as his physical strength

improved. uphill,

Two and

a half weeks

later,

without shortness of breath.

activities without

The

mobile,

his further

Control examinations are

life.

patient

was again

for

up

to

one

hour,

even

able to undertake his daily

any help from outside. His physician wrote: "Overall the patient more secure, less dependent and thereby more confident about

became more improvements

he could walk again

of the patient."

now planned

to

document the obvious

clinical

15

B.M. is a 64 year old patient with irregular heartbeat She has experienced tachycardia (rapid heartbeats as well as irregular heartbeat for two months. The drugs prescribed by her doctor did not bring relief. Then she started to )

my

follow

cardiovascular health recommendations.

"What a smart decision

her letter to me she wrote days the tachycardia stopped and I've

that was! Within a few

In

not experienced any loud or irregular heartbeats.

It's like a miracle. Because of your research I'm able to continue working." Interestingly, the patient had already been

some

taking

of the

recommended

nutrients.

"It

must be the combination

of nutrients in

your recommendation," she wrote.

H.W.

heart

H.W.

lives in

pause

after

weeks

who has been suffering for many years muscle weakness, arrhythmia, and shortness of breath.

a 64 year old patient

is

from

a senior citizens home. He had difficulties climbing stairs and had to about 200 yards when walking because of shortness of breath. Only two

after starting to follow

wrote: "During the past two

my recommendations

weeks

cardiovascular health, he

for

changes have occurred. no longer have difficulties climbing stairs. can walk without pausing for one mile and more, even uphill. Overall, feel more energy and courage to live." Moreover, because of the significant improvements in the patients' health, his physician showed interest in significant

I

I

I

these cardiovascular health recommendations. J.S. wrote: for just

"Dear

Dr. Rath:

How

delightful, after following

2 months one notices the absence

breathe freely. Confidence

is

your recommendations

and the freedom

to

restored as one has increased vigor and endurance.

In

of irregular heartbeats,

a word, one spends less time thinking about their heart and more time enjoying

Your cardiovascular health recommendations have become the answer coronary problems.

I

am happy

to

have

your advanced medical research and

this opportunity of

for

expressing

my

for resolving

gratitude for

your cardiovascular recommendations."

Remarkable Facts About These Patients •

All

patients had

been taking regular drugs. Not these conventional drugs

but nutritional supplements brought ultimate

means



If

this nutritional for

these patients.

This

that vitamin deficiencies are not only frequently related to heart

diseases but are

do

relief to

their

primary cause.

formula can help severely

your cardiovascular health.

ill

patients

-

life.

imagine what

it

can

16

SECTION

A

THE KEYS TO

CARDIOVASCULAR HEALTH

17

THE KEYS TO CARDIOVASCULAR HEALTH The key mechanisms which keep our cardiovascular system healthy have striking parallels to the technical world we live in. The symbols used in the following figure connect these two worlds

-

the technical world outside and the biological world within

our body. This figure can help you memorize the keys to optimum cardiovascular health and

will

help you to better understand your

own body. The keys

to

cardiovascular health are:

Stability Stability of the

we

human body and

its

organs

is

the most important key. Without stability

could not walk upright and our body would

guaranteed by an optimum daily intake

fall

apart.

The

stability of

of vitamin C. Vitamin

C

our body

production of collagen molecules which strengthen the blood vessels and act

reinforcement rods

in

a skyscraper building.

A

is

increases the like iron

reinforced blood vessel wall

is

the

basic protection against atherosclerotic deposits and cardiovascular disease.

Deposit Removal The atherosclerotic deposits in the wall of our blood vessels are like a plaster cast. They are only necessary because the vessel wall has become weakened by vitamin deficiency and threatens to break apart. With continued low vitamin intake over

years these atherosclerotic deposits

mechanism. Optimum

become

many

the body's blood vessel repair

daily intake of vitamin C, vitamin E,

as well as the natural amino

acids proline and lysine can help reduce these deposits and thereby reverse existing

cardiovascular disease. Deposit removal from our arteries daily

waste removal

in

our

Fuel

Cell

The

is like

life.

heart and the blood vessels are

composed

of millions of cells

function determines cardiovascular health. Every single

one

of

whose proper

these cells works

like

a factory. Vitamin C, the B-vitamins, carnitine, coenzyme Q-10, and certain minerals

and trace elements are key

to

critical fuel for

optimum cardiovascular

the body's cell factories and

are therefore a

health.

Antioxidant Protection Cigarette smoke, and the smog polluted

air in

particles called free radicals. Free radicals

our cities contain dangerous small

damage

our body and particularly our

blood vessel system. Vitamin C, vitamin E, and beta carotene are powerful natural antioxidants which can neutralize free radicals before they can cause

cardiovascular disease. Antioxidant protection of our body biological anti-rust protection.

is

damage and

nothing else than a

18

Examples From

Cardiovascular

Technical World

Most Important Supplements

Health

Steel Reinforcement

Rods

Artery

Stability



iiiiii Waste Removal

Vitamin

C

Collagen Fibers

Artery

Vitamin



Vitamin E



L-Proline



L-Lysine

Deposit

Removal Removal

C



of

Atherosclerot

Deposits Cells of Heart

Fuel

And

Blood Vessels

Cell Fuel

C



Vitamin



B-Vitamins



Carnitine



Coenzyme Q10



Minerals

Cell Fuel

Vitamin

C

Antioxidant

Vitamin E

Protection

Beta Carotene

Rust Protection

19

WHY ANIMALS DON'T GET HEART ATTACKS The Body Pool

of Vitamin

Daily Vitamin

Production

in

C

in

Animals

C

is

Many Times Higher Than

Vitamin

Liver

C

in

Humans

Daily Vitamin

Body Pool

Uptake

in

C

Diet

Humans

LOW

Animals



Modern



Canned Food

Diet

HIGH HIGH •

Vitamin Rich Plant Nutrition

While millions of

humans

die every year from heart attacks

diseases are essentially unknown don't get heart attacks

and thus save

must

in

why animals in humans

inevitably lead us to eradicate this disease

millions of lives.

Animals do not get heart attacks because they are able

amounts

and strokes, these

the animal world. Understanding

of vitamin

day ranges between

C 1

own

to

manufacture high

The average amount they produce every and 20 grams (1,000 milligrams 20,000 milligrams) compared

in their

bodies.

-

human body weight. In addition, most animals further increase their body pool of vitamin C by vitamin rich plant nutrition. In contrast, we human beings cannot produce our own vitamin C. Our ancestors lost this ability millions of years ago and ever since we have been dependent on getting enough vitamin C in our diet. To make things worse, our modern diet does not contain the amounts of vitamin C needed for optimum to

health.

As a

Most

of the vitamins are

result, the vitamin

C

pool

in

a hundred times, higher than

in

reinforced

many times more by

destroyed

in

canned food as

the body of most animals

our

human

is

well as

in

cooked food.

often ten times, perhaps

bodies. Consequently, their bodies are

collagen, and their blood vessels are

much more

stable than ours.

Animals don't get heart attacks and strokes because their bodies manufacture enough vitamin

C.

20

HOW

VITAMIN C PREVENTS

HEART ATTACKS AND STROKES

The

following figure illustrates an important discovery: cardiovascular diseases are a

form

of early scurvy.

Column

Optimum

A.

C

intake of vitamin

prevent heart attacks and strokes. Vitamin the most important

is

the single most important

C has many

the production of collagen.

is

functions

Optimum

intake of

produces many collagen molecules which guarantee a strong and wall.

A

blood vessel wall strengthened by vitamin

C does

measure

to

Among vitamin C

the body.

in

elastic blood vessel

not allow atherosclerotic

deposits to develop.

Column

C:

The opposite

of

a vitamin C- stabilized blood vessel wall

during scurvy. Scurvy, the sailor's disease of earlier centuries,

caused by a complete lack is

produced

in

of vitamin

C

in

the

diet. In this

garden hose. Eventually scurvy leads

Column average

of sailors died

B:

the vessel wall

condition very

little

collagen

to

massive blood loss through vitamin Cin

earlier centuries

from scurvy and scorbutic blood loss within a few months.

Cardiovascular diseases

diet contains

As a

wall just like water leaks through a

depleted and leaky blood vessel walls. During the ship voyages

thousands

is

a deadly disease

the body and the blood vessels virtually break apart.

consequence, the blood leaks through the vessel brittle

is

lie

scurvy but not

Our enough to

many

years, fat

exactly between these two conditions.

enough vitamin C to prevent open wall. As a consequence,

guarantee a stable blood vessel

over

globules and other risk factors from the blood enter the blood vessel wall and lead to the development of atherosclerotic deposits. Local growth wall further increases these deposits. Deposits

heart attack; deposits

Optimum

in

in

of cells inside the vessel

the arteries of the heart lead to

the arteries of the brain lead to stroke.

daily intake of vitamin C in our diet stabilizes the walls of the blood vessels and helps prevent heart attacks and strokes.

21

ABC

Cardiovascular Disease

C

Intake

a Form of Early Scurvy

Chronic

Optimum Vitamin

Is

Vitamin

C

Total Vitamin

Deficiency

C

Depletion (Scurvy)

Collagen

Molecules

Cross Section Through Artery

Consequences for Arteries

Death From Scurvy and Blood Loss Through Leaky Healthy

Deposits

Artery

Develop

Heart Arteries Heart Attack

Blood Vessels

j^

Brain Arteries:

Stroke

22

VITAMINS PREVENT HEART DISEASE THE CLINICAL EVIDENCE -

Vitamin C Cuts Heart Disease Rate Almost

(Documented

in

in

Half

11,000 Americans Over 10 Years)

One

Vitamin E Cuts Heart Disease Rate by More Than

(Documented

in

Third

36,000 Americans Over 6 Years)

Beta Carotene (Provitamin A) Cuts Heart Disease Rate

Almost

Half

in

(Documented

36,000 Americans)

in

Prescription Drug Has Ever Been Shown to Help Prevent Heart Disease Similar to These Vitamins

No

Vitamins belong to the most powerful agents fact

results of that

in

the fight against heart disease. This

has been established by studies on thousands the largest recent studies are

anybody questioning the value

of

people over

shown above. These

many

years.

The

results are so clear

disease can

of vitamins in the prevention of heart

safely be considered as uninformed.

The best documented vitamins

for the

vitamin C, vitamin E, and beta carotene.

prevention of cardiovascular diseases are

These vitamins are

they prevent the biological rusting of our blood vessels.

ever shown to cut the rate

optimum measure Now, a

for heart

scientific

existing deposits

breakthrough has been

and beta carotene

made which enables

in

our arteries

-

more

is

the basic

in

to

prevent

effectively but also to help

remove

us not only

without surgery. This breakthrough

possible by recent discoveries about the

Nutritional

and

was

prevention of cardiovascular diseases.

the development of cardiovascular diseases

deposits develop

prescription drug

diseases as effectively as these vitamins. Thus

dietary intake of vitamin C, vitamin E, for the

natural antioxidants

No

mechanisms

of

how

was made

atherosclerotic

the wall of our blood vessels.

supplements can help prevent cardiovascular diseases.

)

23

A NEW RISK FOR YOUR HEART TIMES GREATER THAN CHOLESTEROL

10

Lipoprotein(a)

Lipoprotein(a)

is

by

far

the greatest

known today

risk factor

for

Heart attacks







now we have been

Until

cholesterol') are the

which

name

a 10 times greater

is

bad cholesterol"

of this "very

What

is

blood

in

them

is

is

A new

risk for

risk factor for

fat

molecules are transported

low density lipoprotein, LDL. Lipoprotein(a)

is

an LDL

the normal function of lipoprotein(a)?

Whenever our blood vessels

molecule.

is

fat

globule with a

called apoprotein(a) or

fatty

deposits and to clogging

but the adhesive tape: less

less risk for heart disease.

-

vessel walls develop small lesions. aid

is

lipoprotein fat globule stick inside the blood

Many of these sticky fat globules then lead to arteries. The main problem is not the fat globule

What

our

in

The most well-known among

adhesive tape wrapped around. This adhesive

The adhesive apo(a) makes the

adhesive

your heart has been

lipoprotein(a).

vessels. of

Apo(a)

your heart than "bad cholesterol". The

and other

lipoprotein(a)? Cholesterol

Adhesive

(low density lipoprotein or "bad

the form of small fat globules called lipoproteins.

biological

apo(a).

LDL

a)*—

our blood vessels. Recent scientific

risk factors for

discoveries have antiquated this theory. identified

Xj

Fat Globule|

^Wj

told that cholesterol or

main

|

(

Strokes Clogging of bypass vessels after coronary bypass surgery Clogging after angioplasty



ambulance:

low vitamin

C

lipoprotein(a)

in

Lipoprotein(a)

weakened by

are

In this situation,

is

the body's top repair

vitamin

C

deficiency, the

lipoprotein(a) functions as a

first

enters the vessel wall and tries to repair the damage. However, with

it

the diet over

many

years, this repair goes on and on:

molecules are deposited

in

many

fatty

the blood vessel wall, and eventually

atherosclerotic deposits develop.

We

have gained a new understanding

of

Heart attacks and

cardiovascular disease.

strokes are caused by an overcompensating or overshooting repair

blood vessel walls

weakened by a

deficiency

in

Atherosclerotic deposits are the bodies plaster cast to stabilize vessels. -

Lipoprotein(a)

becomes

is

the most

the greatest risk factor

so important,

why

effective repair

molecule and

for heart attacks

haven't you heard about

mechanisms

vitamins, particularly

-

and strokes.

in

for

vitamin C.

weakened blood

with ongoing repair If

lipoprotein(a)

it?

Cardiovascular disease is an overshooting repair mechanism for blood vessels weakened by vitamin deficiency.

is

:

:

24

WHY YOU HAVE HEARD ABOUT CHOLESTEROL BUT NOT ABOUT LIPOPROTEIN(a) Why

Cholesterol

Is

Why

Known

Lipoprotein(a)

Reason #1

Reason #1

Cholesterol

was found

long

Reason #

Cholesterol

Lipoprotein(a)

ago

newly

No

l

clinical

studies

are available

Clinical studies are rare

i

i

results of these studies are

published

in

No

medical journals,

newspapers, and other media

studies are published

journals,

in

medical

newspapers and other media

i

I Hardly anybody

Everybody

knows about

2:

which lower the risk from lipoprotein(a)

i

The

a

prescription drugs are available

drugs are available

Many

is

identified risk factor

Reason #

2:

lowering prescription

-

Unknown

Is

knows about

cholesterol

Three More Reasons To inform you about

Why

lipoprotein(a)

-

This Book

Is

lipoprotein(a)

Needed

the risk factor for your heart you had

not heard about despite the fact that

it

is

ten times

more dangerous than

cholesterol.

To

inform you about the value of vitamin C, vitamin B3, lysine and proline

-

lipoprotein(a)

and affordable nutrients which lower the risk from and which can reverse existing cardiovascular disease.

You

little

effective,

will

safe,

get

education from elsewhere as long as no patentable it may take ten years or more

prescription drugs are available. Moreover, until

such drugs could become available.

L

25

A SCIENTIFIC BREAKTHROUGH THE REVERSAL OF EXISTING CARDIOVASCULAR DISEASES WITHOUT SURGERY Vitamins and Natural Arr lino Acids



• • •

Removal



Wmt ^^rjrtprs^s'

of

dream

,.

m

m ^^S %'^^K

Reduction of 'Atherosclerotic Tumor'

^r

and

Other Risk Factors from Deposits

old

Atherosclerotic Deposits

Vitamin C Vitamin E L-Proline L-Lysine

Lipoprotein(a)

An

Can Reverse

Caused by

Cell

Growth

Inside the Vessel Wall

mankind has come true: the non-surgical reversal of existing The nutritional supplements vitamin C, and the natural amino and L-lysine are the keys to reverse existing deposits and thereby

of

cardiovascular disease. acids L-proline

reverse heart disease.



Blood

vessel

What

stability.

blood vessel wall. This •

A

are the secrets behind this breakthrough?

Vitamin

teflon layer in the vessel wall.

proline

C

restores stability and elasticity of a

weakened

the basis for restoring blood vessel health.

stability is

High intake of the natural amino acids lysine and

provide a teflon layer around lipoprotein(a) and

teflon layer helps release lipoprotein(a)

and other

fat

in

the blood vessels. This

globules from their deposits

in

blood vessel walls

is

the blood vessel walls. •

Decrease of the

'atherosclerotic tumor'.

part of the overshooting repair

this 'tumor'

of cells in the

mechanism causing a small

inside the vessel wall. Vitamin E,

decrease

Growth

and thereby

and

'atherosclerotic tumor'

potentially vitamin C, lysine

and

proline

can

further reverse existing cardiovascular disease.

Until now coronary bypass surgery and angioplasty of the coronary arteries have been the standard treatments to reverse existing heart disease. On the basis of the above discoveries, safe and affordable nutritional supplements can become the

method

of

choice to reverse existing heart disease without surgery.

Nutritional

supplements can help reverse existing heart disease without

surgery.

26

WHEN TO START PROTECTING YOUR BLOOD VESSELS AND YOUR HEART Start Protecting

Healthy Artery

Your Blood Vessels Early

in Life

Atherosclerotic

Deposits and

Deposits

Additional Blood Clot

Seconds

Many Years

t Start Protecting

Your Blood Vessels Here

The changes in a two stages. The first stage, continues over many years. The second

At birth the walls of the arteries are clean and

show no

blood vessel leading to a heart attack and stroke occur the development of atherosclerotic deposits,

deposits.

in

stage, the formation of a blood clot occurs within a few seconds. Blood clots frequently form around atherosclerotic deposits leading to a total interruption of the

blood flow and thereby to heart attacks and strokes. This happens so fast that

many

patients die immediately without being able to reach a hospital.

The time

to start protecting

your blood vessels and your heart

Since atherosclerotic deposits have been found younger, preventing the build-up of deposits early heart attack

in

is

during the

in life is

the safest

way

right time to start protecting

stage.

to prevent

.

The

first

the arteries at age twenty and

your heart

is

now!

a

27

HOW YOU CAN IMPROVE THE PERFORMANCE OF YOUR HEART Optimum

Intake of Cell Fuel Nutrients Improves Heart Function Cell Fuel Nutrients

C



Vitamin



Carnitine



Coenzyme Q10

•Vitamin 61,62,63,65,66,612 •

Minerals & Trace Elements

Regular

Low

20 mg/dl

-

Risk for Heart Disease

Medium Risk

40 mg/dl

40 mg/dl

High Risk for Heart Disease

between one

Lipoprotein(a) blood levels vary greatly

we know

Disease

for Heart

individual

about the factors influencing the lipoprotein(a) levels



Lipoprotein(a) levels are largely determined by inheritance.



Special diet does not influence lipoprotein(a) blood levels.



None

of the presently available lipid-lowering prescription

and another. What do

in

the blood:

drugs lowers

lipoprotein(a)blood levels.



C and vitamin B3 can lower blood levels of lipoprotein(a) (see Section E). Together with the natural amino acids lysine and proline (see Section D) the risk from lipoprotein (a) can be significantly lowered by nutritional supplements.

Vitamin

Everybody should know

their lipoprotein(a)

blood

level.

The above

figures give you a

basic guideline to properly read the results of your lipoprotein(a) blood test and to find your personal risk. People whose lipoprotein(a) concentrations are greater than 30

mg/dl (milligrams per hundred

cardiovascular disease.

On

have a two-fold increased risk of developing the following page you will find a more detailed milliliter)

interpretation of the risk from lipoprotein(a) testing

in

Further Information: Inherited Lipoprotein(a) Levels:

1990. Risk Factor Analysis: Armstrong 1

989; Rath

M

1

991

a,

1

992c and

1

992e.

VOW

combination with LDL testing.

Utermann

G

1989: Koschinsky

1986. Vitamin Therapy: Carlson LA

M

46

LIPOPROTEIN(a),

AND LDL-CHOLESTEROL

HOW TO INTERPRET YOUR PERSONAL Most

of

know our LDL-cholesterol

us

measurements

of

determine your

risk for



Low

LDL- cholesterol

in

factor.

High levels of

The explanation

are therefore

much

will

anybody knows

help you to

their

interpret your blood

combination with lipoprotein(a) and

to better

cardiovascular disease:

30 mg/dl) and high

levels of lipoprotein(a) (below

(above 150 mg/dl).

levels but hardly

This page

blood levels.

lipoprotein(a)

RISK

is

simple.

LDL

LDL

levels of

cholesterol

cholesterol alone are only a moderate risk

The LDL

particles lack the

adhesive apo(a) and

less likely to stick inside the blood vessel wall

and much less

contribute to the development of atherosclerotic deposits.

likely to

High levels of lipoprotein(a) (above 30 mg/dl) and low levels of LDL cholesterol (below 150

mg

High levels of lipoprotein(a)

dl).

the blood, even

in

when LDL

cholesterol levels are low, increase your risk of developing cardiovascular disease

about twofold. You already know the reason: via the adhesive apo(a), the lipoprotein(a) particles stick inside the blood vessel wall

and

millions of

them

eventually lead to the buildup of atherosclerotic deposits.

High levels of lipoprotein (a) levels and,

in addition,

LDL

cholesterol levels high.

Patients with this combination of risk factors are two to five times

more

likely to

suffer a heart attack or stroke than a person with normal levels of these risk

Why

factors.

is

On

that?

blood vessel wall.

On

additional lipoproteins

the one hand, lipoprotein(a) particles stick inside the

the other hand, the adhesive apo(a) can also capture

and

retain

globules are the most important

The

particles.

wall by

many

development

M

LDL

fat

among these lipoproteins gluing to lipoprotein(a) many LDL and VLDL fat globules in the vessel

lipoprotein(a) particles already deposited there further of atherosclerotic deposits. This in

is

why

speeds up the

the risk for heart diseases

persons with high lipoprotein(a) blood levels as well as high

levels.

Further Information:

1990; Rath

inside the blood vessel walls.

additional retention of

increases manifold

LDL blood

them

1992e.

Serum Lp(a) Concentrations: Armstrong VW 1986; Seed BH LDL - Cholesterol Concentrations: See Also Recommendations

From the American Heart Association.

47

Possible Risk Factor

Combinations in

Your Blood

Your Risk for Heart Disease With These

Combinations

LDL

Cholesterol

Moderate Risk

Lipoprotein(a)

LDL Binds

Poorly to

Blood Vessel Wall

LDL

Cholesterol

High Risk Lipoprotein(a) Lipoprotein(a)

Binds Strongly

to

Blood Vessel Wall

LDL

Cholesterol

Very High Risk Lipoprotein(a) Lipoprotein(a)

Binds Strongly to Blood Vessel Wall + Lipoprotein(a)

Captures Additional

LDL

Fat Globules

48

RISK FOR LIPOPROTEIN(a) DEPOSITS INCREASES WITH HIGH LIPOPROTEIN(a) BLOOD LEVELS The Higher The More

Lipoprotein(a) Blood Levels

Lipoprotein(a)

Is

Deposited

Lipoprotein(a) Levels in

the Blood

Amount

How

important

figures



First,

on

this

the

more

lipoprotein(a) •

is

it

to

know your

page and on the lipoprotein(a) is

Second, the size

of Lipoprotein(a)

Deposited

the Walls of Blood Vessels

in

lipoprotein(a) blood levels

can be seen from the

following page:

you carry

actually deposited

in

in

your blood, the greater

is

your

risk that this

your blood vessels.

of atherosclerotic deposit

increases with the amount of

lipoprotein(a) deposited.

The above

figure

shows

that the higher the lipoprotein(a)

the risk that lipoprotein(a)

is

important finding from our studies

in

human

arteries.

colleagues from Baylor College of Medicine atherosclerotic deposits surgery.

in

The researchers

lipoprotein(a) blood level

in

blood levels are, the greater

deposited inside the vessel

in

wall. This is

Similar results

another

were obtained by

Houston, Texas. They investigated the

the venous blood vessels used for coronary bypass in

Texas came

the patient, the

to the

more

same

conclusion: the higher the

lipoprotein(a)

was deposited

in

the

bypass blood vessels. Another important question was whether there

is

a relation between the size

blood vessel deposit and the amount of lipoprotein(a) deposited therein.

Further Information: Rath

M

1989; Cushing

GL

1989.

of the

49

EXTENT OF ATHEROSCLEROTIC LESION INCREASES WITH AMOUNT OF LIPOPROTEIN

(a)

DEPOSITED The Larger The Vessel Wall Lesion

The More

Amount

Lipoprotein(a)

Is

-

Deposited

of

Lipoprotein(a)

Found Deposited

in

Blood Vessel Walls

i Stage

of

Normal Blood Vessel Wall

Atherosclerotic

Deposits

Advanced

Early Deposits

Atherosclerotic

(Fatty Streaks)

Lesions

The

larger the size of atherosclerotic deposits

found

lipoprotein(a)

is

deposits from

human

in

arteries

showed

more

the vessel walls, the

be stuck inside these deposits. Analysis

to

of several

hundred

the following results:



Normal blood vessel walls generally contain some



Early deposits (fatty streaks) already have a

much

lipoprotein(a).

higher

amount

of

lipoprotein(a) accumulated. •

Advanced

deposits, the atherosclerotic plaques about to clog the artery and to

cause heart attacks and strokes, contain the highest amount

The conclusion from these studies you can reduce the deposition decrease your

is

that by lowering your lipoprotein(a) blood levels

of lipoprotein(a) in the

risk for heart attacks

of lipoprotein(a).

blood vessel wall and thereby

and strokes. Two vitamins, vitamin C and vitamin

B3, are the only factors known to reduce effectively the blood levels of lipoprotein(a). These and further therapeutic recommendations will be extensively discussed in the Section D and Section E of this book.

On

the following pages

entirely

I

would

like to

new understanding about

Further Information: Beisiegel

U 1990; Rath

Lipoprotein(a)

M

1989.

share with you how these discoveries lead

to

an

the nature of cardiovascular diseases.

in

Human

Blood Vessels: Niendorf A 1990:

50

THE LIPOPROTEIN(a)

Vitamin

VITAMIN C CONNECTION

-

Humans

Animals

NO

YES

YES

NO

YES

NO

C High

High

Lipoprotein(a)

Cardiovascular Diseases Frequent

Perhaps the most important found

in

human beings

fact

about lipoprotein(a)

is

while other living beings have

1987, while researching the role of lipoprotein(a)

in

that this risk factor

little

or

is

no lipoprotein(a)

cardiovascular disease,

I

primarily at

all. In

made an

vitamin C connection. noticed that animals own bodies have little or no lipoprotein(a). In contrast, we human beings, unable to manufacture our own vitamin C, apparently make ample use of lipoprotein(a). Moreover, we thereby evidently increase the risk for cardiovascular

amazing discovery: the producing vitamin

C

lipoprotein(a)

-

I

in their

diseases.

The

lipoprotein(a)



high vitamin



low vitamin

-

vitamin

C levels C levels

-

-

C

little

connection says: or no

need

for lipoprotein(a)

molecules

great need for lipoprotein(a) molecules.

Immediately following the discovery of the lipoprotein(a)

conducted the

first clinical

test to

high lipoprotein(a) blood levels risk factor.

The encouraging

prove

this discovery: In

was given

results

were

vitamin later

Section

F).

What

the secret behind the lipoprotein(a)

is

Further Information: Rath

M

1990.

-

C

vitamin

C

connection,

first

I

person with

with the specific aim to lower this

confirmed

vitamin

-

1987, the

C

in

a

pilot clinical

connection?

study (see

51

THE PRIMARY CAUSE OF CARDIOVASCULAR DISEASE

VITAMIN C DEFICIENCY

BLOOD VESSEL STABILITY

-

The

IS

lipoprotein(a)

-

vitamin

C connection

THE KEY

IS

-

leads us directly to the nature of

cardiovascular disease:

The underlying cause



of cardiovascular

disease

is

a low intake of vitamins,

particularly of vitamin C.

Vitamin



C

deficiency leads to lesions and instability

in

the blood vessel walls, and

the cell barrier between the blood stream and the blood vessel wall Lipoprotein(a) molecules, the body's



first

becomes

leaky.

aid molecule for blood vessel repair, enter

the blood vessel wall. Lipoprotein(a)



up

is

an

for the lack of

ideal repair

adhesive apo(a) renders •

molecule because the adhesive tape apo(a) makes

in the blood vessel wall. In this way the weakened blood vessel wall. C over many years this repair mechanism overshoots and

collagen molecules

With low intake of vitamin

stability to the

atherosclerotic deposits develop.

Thus, atherosclerotic deposits are an overcompensating or overshooting repair process

of the vessel wall

which

is

chronically

weakened by

vitamin deficiency.

Neither cholesterol, nor fat globules, nor any other blood risk factor

cause

of cardiovascular disease.

instability of the

blood vessel wall. Vessel wall

lipoprotein(a)- vitamin in

The primary cause

C

of cardiovascular stability

connection. Evidently, blood vessel

is

is

the primary

disease

is

the

the key behind the

stability

can be achieved

two ways:

Alternative #1

Alternative #2:

An optimum

:

production and

in

intake of vitamin

C

resulting

in

optimum collagen

blood vessel reinforcement.

By the deposition

of lipoprotein(a)

and

of other risk factors resulting in

the formation of atherosclerotic deposits. Atherosclerotic deposits are the blood

vessels plaster cast which stabilize the vessel walls weakened by vitamin deficiency.

summary, the primary cause of cardiovascular disease is a blood vessel wall which weakened by an insufficient intake of vitamin C. On the following pages will share with you the already available evidence for this new understanding of this disease. In

is

Further Information: Rath

I

M

1991a.

52

Two

Alternatives to Stabilize Your Blood Vessels

Alternative

#

1

Alternative

#2

Molecules

Responsible for Stability

Q&s* Collagen Molecules

Repair Molecules e.g. Lipoprotein(a)

A Look Our

Inside

Arteries

Healthy Artery Wall:

Reinforced by Sufficient

Collagen Molecules

You Have the Choice by

Optimum Vitamin C Intake

in

Your Diet

Weakened Stability

Artery Wall:

Provided by

Atherosclerotic Plaster Cast

Insufficient Vitamin

Intake

Which Alternative Do You Prefer?

in

C

Your Diet

53

THE PRIMARY CAUSE OF CARDIOVASCULAR DISEASE

VITAMIN C DEFICIENCY

IS

EARLY CLINICAL EVIDENCE

-

1941: The Canadian

-

Paterson reports that more than 80% of his heart disease patients have vitamin C deficiency as a significant risk factor. cardiologist J.C.

1948: The American doctors R.W. Trimmer and C.J. Lundy

70%

report that

coronary

of their patients with

C blood

artery disease have very low vitamin

levels.

Already half a century ago

first

cardiovascular diseases have

much lower

persons. This study Patterson.

He found

was published

that

In

C

showed

C

vitamin

or four out of five

-

patients

that

with

blood levels than healthy

by the Canadian cardiologist J.C.

1941

in

more than 80%

disease suffered from vitamin

reports

clinical

-

of his patients with heart

deficiency.

1948, the American doctors R.W. Trimmer and C.J. Lundy found similar results

their

coronary heart disease patients.

In

the medical journal

they reported the measurements of vitamin

diseases.

Two

C

blood levels. Moreover,

were widest spread among

Thus, a low vitamin risk factor for

blood levels

in

556 patients with various were found to have

out of three patients with coronary heart disease

very low vitamin deficiencies

C

in

American Practitioner

C

intake

among

all

diseases investigated vitamin

heart disease patients.

and low vitamin C blood

levels

were found

to

be leading

cardiovascular diseases long ago.

Measurements

of vitamin

C

concentration

in

the blood vessel wall

showed

results.

Further Information: Paterson

JC 1941 Trimmer ;

RW

1948: Knox

EG

1973.

similar

54

THE PRIMARY CAUSE OF CARDIOVASCULAR DISEASE FURTHER EVIDENCE

VITAMIN C DEFICIENCY

IS

-

Less Vitamin

Vitamin

C

-

More Cholesterol

Is

Deposited

C

Concentration in

Blood Vessel Wall

Amount

of Cholesterol

Deposited

A

low concentration of vitamin

the wall.

1979

In

C

in

Blood Vessel Wall

the blood vessel wall leads to fatty deposits inside

Hanck and

Dr. A.

in

his

colleagues from the University

of Basel,

Switzerland published an important study. They measured the concentrations of vitamin

C

human

in

blood vessels, and at the

of cholesterol deposited.



The lower

The

the vitamin

C

figure

same

above shows

time they determined the amount

their findings.

content of the vessel wall, the more cholesterol

was

deposited. •

A

Dr.

blood vessel wall

Hanck and

cholesterol

in

his

rich in

vitamin

C was

evidently protected against fatty deposits.

colleagues confined their study

to

measuring the deposition

the vessel wall; they did not include lipoprotein(a)

in

of

their analysis at

that time.

On

the

previous pages

we have learned how vitamin deficiencies lead to we have seen that patients with heart disease C concentrations in their bodies. On the following page

cardiovascular disease. Moreover, frequently have low vitamin will

share with you the proof

Further Information:

I

for this

Hanck A 1979.

new understanding

of cardiovascular disease.

55

THE PRIMARY CAUSE OF CARDIOVASCULAR DISEASE - THE PROOF -

VITAMIN C DEFICIENCY

Vitamin

C

deficiency

revolutionary

new

the

is

IS

primary cause

insight into the

of

cardiovascular disease.

This

number one killer diseases has, of course, to be be shown that a low intake of vitamin C in the diet

The key question is: can causes atherosclerotic deposits to develop? For ethical reasons, this question can, of course, not be answered by a study using human beings. is therefore necessary to answer this important question with a suitable animal model. proven.

it

actually

It

This animal model

own

C and

vitamin

is

available.

Guinea

pigs, like

human

beings, cannot produce their

they are therefore also dependent on sufficient intake of vitamin

C

What happens to blood vessels of guinea pigs they receive a diet low in vitamin C? To answer this question the following study was carried out: A group of guinea pigs received 60 mg of vitamin C in their diet (compared to the human body weight). This amount was chosen because the 'official' Recommended Daily Allowance (RDA) for vitamin C is 60 mg. A second group of guinea pigs received about 5,000 mg vitamin C per day (compared to the human body weight). After five weeks the arteries of both groups of animals were analyzed. The dramatic findings are shown on the next page: Picture A: Animals on a diet rich in vitamin C showed no atherosclerotic deposits. in

the diet.

if



Optimum collagen reinforcement effectively. Picture A shows the main in •

In

contrast, animals on a diet low

guinea pig with

in

in

their arteries. Picture

insufficient vitamin

atherosclerotic deposits (arrows)

is

protected

their

vessels

blood

optimum vitamin C

the diet. Note that no fatty deposits (white areas) are visible.

Picture B:

atherosclerotic deposits

It

evidently

artery of a guinea pig with

in

C

in

the diet.

C

rapidly

developed

B shows the main

artery of a

vitamin

The white areas represent

the

the blood vessel wall.

important to understand that both groups of animals received exactly the

same

amounts of cholesterol and other fats in their diet. Vitamin C was the only factor too varying between the two groups. This experiment thus proves that one factor little vitamin C in the diet causes atherosclerotic deposits to develop. As mentioned above, the guinea pig and the human body share exactly the same problem both are dependent on optimum intake of vitamin C in the diet. Because of this fact we can -

-

-

directly translate the results of this

experiment

and

A

direct

we were

cause

experiment

able to scientifically

of heart attacks

note by the author:

to

our

human bodies. Thus, with this C deficiency is the primary

prove that vitamin

and strokes.

Animal experiments should be kept

at

an absolute minimum.

to save These experiments should be limited to will likely stay shown human lives. The experiment described above and the figure them. with my readers throughout their lives, and hopefully will help to prolong

gaining information which can help

Further Information: Willis

GC

1952: Gore

I

1965: GinterE1978: Rath

M

1990b.

56

57

VITAMIN C DEFICIENCY

THE PRIMARY CAUSE OF CARDIOVASCULAR DISEASE - THE PROOF -

Let us

now have a

vitamin

C

wall of

closer look inside vessel walls with sufficient and insufficient

The above

content.

IS

A and B show

pictures

guinea pigs magnified under a microscope.

you a look inside a human blood vessel. •

Picture

Two

A shows

We

a cut through the blood vessel

For comparison, picture

the blood vessel wall from a guinea pig on a high vitamin

features are important to note.

blood stream and blood vessel wall

intact.

Thus, few

risk factors

a regular structure of collagen molecules inside the blood vessel structure guarantees

Picture

B shows

optimum

stability

blood vessel wall

open

for

many

and

is

First,

deficient blood vessel wall



Figure

these blood vessel walls.

C

diet:

evident that this blood vessel wall

is

C

It

is

shows a very disorganized collagen stability

and

pattern.

elasticity to the wall.

vessel walls develop atherosclerotic deposits as a

C shows

shows

from the blood stream. Second, the vitamin

collagen molecules are unable to provide

weak

elasticity of

itself

the barrier between the blood stream and

disrupted and broken.

risk factors entering

diet:

wall. This regular

the blood vessel wall from a guinea pig on a /ow vitamin

Again two features are noteworthy:

C

can enter the

blood vessel wall from the blood stream. Second, the blood vessel wall



gives

the barrier (fine white line) between the

First, is

C

can make the following observations:

'cast' to

a similar slice through an atherosclerotic

improve

human

artery.

These These

stability.

Again,

disrupted collagen molecules are the basis for the development of atherosclerotic deposits.

Please compare picture

Our new understanding

of

C

with pictures

cardiovascular disease

is

A and

B.

summarized on

the next page.

58

The

Principles of Cardiovascular Disease



The primary cause

disease

is

weakness



vitamin of the

C

of

cardiovascular

deficiency leading to

blood vessel walls.

Cardiovascular disease begins with the

deposition of repair molecules inside the

blood vessel wall.



If

vitamin deficiency continues over

many

years these repair molecules become risk factors, the vessel wall repair mechanism overshoots, and cardiovascular disease

develops.



Lipoprotein(a)

is

the

most

effective

vessel wall repair molecule and therefore -

over time

-

becomes

the greatest risk

factor for cardiovascular disease.

59

HEART ATTACKS, STROKES, AND PERIPHERAL VASCULAR DISEASES Why Some Forms

of

Cardiovascular Diseases Are More Frequent Than Others Peripheral

Heart Attacks

Strokes

(7 Million)

(3 Million)

Vascular

Disease (1

Weak

Million)

Blood Vessel Wall

#1

#1

#1

Arteries Close to Heart

#2

#2

No

Mechanical Stress on Blood Vessel Wall

#3

No

No

Optional

Optional

#2

(Vitamin

C

Deficiency)

Higher Blood Pressure

in

High Levels of

Blood Risk Factors

We

can now explain why heart attacks are more frequent than strokes and

more frequent than the clogging of arteries in the bodie's periphery: Seven million Americans are diagnosed with diseases of the heart arteries. Three million Americans are diagnosed with diseases of the brain arteries. An estimated one million Americans are diagnosed with cardiovascular, diseases in other organs and the extremities of the body (periphery).

strokes •

• •

The answer for this phenomenon is summarized in the above figure: • The underlying cause of all forms of cardiovascular diseases is a weakness

of

the blood vessels as a result of vitamin deficiencies (#1). •



The more additional local factors challenge more often the vascular system fails at this

One

additional local challenge

is

this instable

blood vessel wall the

specific location.

the higher blood pressure

in

the arteries of the

heart and the brain explaining heart attacks and strokes (#2). •



The greatest

challenge

local

the mechanical stress for the coronary arteries

is

explaining heart attack as the leading cardiovascular disease (#3). High levels of blood risk factors alone cannot explain the local failure of the

cardiovascular system

in

form

of heart attacks or strokes. But

if

these

risk

factors are present in addition heart attacks and strokes occur earlier. direct damage In contrast, peripheral vascular diseases are caused by a ,



certain blood risk

factors to the wall of the entire blood vessel pipeline.

Vascular diseases

in

smokers and diabetics are examples (Section

E).

of

60

THE PIPELINE PHENOMENON new understanding suddenly

This

enables us puzzle

an unsolved

to explain

our bodies: the pipeline

in

phenomenon. The human blood vessel system

a pipeline.

is

were cut open,

pipeline

measured

and

Each

would be huge.

it

small square

this

If

laid out,

the adjacent figure

in

represents two square yards (about

two square meters). The blood vessel surface area of one person

amounts to half the size of a football The black square in the middle

field.

represents the

area

surface

those arteries which

of

a million

fail

times over: the coronary arteries

where heart attacks occur. As you can see arteries

this

compared

Why

is

area

coronary

of the

only a small fraction

is

when

whole pipeline. there only one black square to the

and why are not

the squares

all

black?

All

presently available theories for cardiovascular diseases

concentrations of a

risk factor in

theory, for example, wall

assumes

and thereby lead

evident that

in this

the blood are the primary

that high cholesterol

development

to the

case the damage

to the

levels

assume

villains.

damage

The

the blood vessel

of atherosclerotic deposits.

It

is,

blood vessel wall would occur

vessels throughout the body. Just as bad water quality

damages

that high

cholesterol

however,

in all

blood

a water pipeline

everywhere, cholesterol would lead to the clogging of arteries, veins, and capillaries throughout our body. fingers, nose,

elbows

If

not bad water quality

water pipeline. the heart

is

The very

is

is

suffer from infarctions of our In

our picture above,

in

similar technical

logical in

problems

all

obviously not the case.

the primary problem but the instability of the wall of the

local failure of

our cardiovascular system in

in

the arteries of

combination with

these coronary arteries. The logic behind the figure above

does not take a medical degree

The

we would

the result of the instability of the blood vessel wall

great mechanical stress

new ways

valid,

essentially every part of our body.

squares would turn black. This

Thus

was

theory

this

-

in

-

it

is

a simple physical problem.

A plumber

finds

his daily work.

to the pipeline phenomenon directly leads us to the prevention and treatment of cardiovascular disease.

answer

61

VITAMIN C AND OTHER ESSENTIAL NUTRIENTS

CAN PREVENT AND REVERSE CARDIOVASCULAR DISEASES In this

we have seen

section

that the primary

cause

of

cardiovascular disease

the instability of the blood vessel walls caused by a deficiency primarily

The

in

sections of the book

following

a powerful

is

to treat virtually

Aim Number One •

way

(Section C):

Vitamin



Beta Carotene



Other essential nutrients

D):

free radical

Vitamin



Vitamin E



in

L-Proline



L-Lysine



Other essential nutrients

your blood vessel walls

Vitamin



Vitamin



-

(Section E): Lowering the levels of lipoprotein(a)





-

C

*

of other risk factors for cardiovascular

Needed:

stability

damage

Reversing cardiovascular disease by

decreasing atherosclerotic deposits

and

dietary

C

Vitamin E

Aim Number Three

that

C

B3 (Niacin) vitamins B Other Other essential nutrients

vitamin

your blood vessels and your heart

Maintaining and restoring the

and preventing



Aim Number Two(Section Needed:

show you

will

to protect

any cardiovascular disease you may have.

of your blood vessel walls

Needed:

is

vitamins,

vitamin C.

supplementation

and

in

diseases

in

your blood

62

NOTES

63

SECTION C

HOW TO PREVENT CARDIOVASCULAR DISEASES WITH NUTRITIONAL SUPPLEMENTS

This Section Will Summarize the Evidence That

Vitamin C, Vitamin

E,

and Beta Carotene Can

Prevent Cardiovascular Diseases

64

-5^!

Deposits

Vitamin

C reduces

Prevents

Spasm

3.

Blood Vessel Wall

Prevents High Blood Pressure

the risk for cardiovascular disease

in

many

different

by preventing the buildup of deposits



by relaxing the blood vessel wall and lowering the blood pressure



by decreasing the

found

G

of this book).

In

the previous chapters

nutrients

in

benefits of vitamin

the molecules of inheritance (genes)

in

ways:

blood clotting and keeping the blood at optimum viscosity

These broad cardiovascular is

Blood Clot

Formation



risk of

Prevents Risk

for

we have

C in

are no coincidence.

our bodies

described the role

The explanation

(for details

of vitamin

C and

see Section

other essential

preventing the buildup of atherosclerotic deposits and other forms of

thickening of the blood vessel wall.

The next pages describe the

role of vitamin

C

helping to relax the blood vessel wall, thereby lowering the blood pressure.

Further Information: Review: Clemetson Anti-Clotting Effect: Spittle

CR

CAB 1989: Rath M 1991a and 1992a. AK 1979 and 1985: Salonen JT 1991

1973; Bordia

in

112

HOW

LOWERS HIGH BLOOD PRESSURE VITAMIN C

C Supplementation Lowers

Vitamin

Blood Pressure

by Relaxing the Wall of the Blood Vessels

Low Vitamin C

Optimum Vitamin C

Intake



Contracted Blood Vessels



High Blood Pressure





High blood pressure

Vitamin

C

in

vitamin

is

j^

Relaxing Factors

*^

Relaxed Blood Vessels Normal Blood Pressure



deficiency

generally the result of a blood vessel wall suffocating from a

C and

other essential nutrients.

deficiency increases the blood pressure by



leading to a long term buildup of atherosclerotic deposits



causing spasms of the blood vessel

Vitamin

C

wall.

supplementation lowers high blood pressure by



preventing and reversing atherosclerotic deposits



by relaxing the blood vessel

The blood vessel

wall.

relaxing effect of vitamin

C

is

shown on

increases the concentration of small relaxing factors blood vessel wall. As a vessel

result,

and an

initial

a.

C

page. Vitamin

oxide, prostacyclin)

in

the

is

lowered.

This relaxing effect can occur

blood pressure lowering effect of vitamin

C may be seen

few days.

Further Information: Vitamin

1991

(nitric

this

the blood vessel wall relaxes, the diameter of the blood

increases and the blood pressure

rather quickly within a

Intake

High Levels of

C and

Prostacyclin: Beetens J 1986. Nitric Oxide: Rath

M

113

LOWERS BLOOD PRESSURE

VITAMIN C

Vitamin

C Supplementation Decreased

High Blood Pressure

Vitamin C Per Day Lowered High Blood Pressure

One Gram in

A number

Two Out

of

Three Patients

showing

of studies are available

increases the

risk for high

investigations

was

in

blood pressure of 10,372 persons of

McCarron and his colleagues from the The researchers analyzed the all ages in relation to their dietary habits.

that the single

Portland.

most important

factor associated with high blood

pressure was a low dietary intake of vitamin deficiency

amount In

was

C and

A

vice versa. Vitamin

also found to increase the risk for high blood pressure while the

of cholesterol in the diet

the study

C

carried out by Dr.

Oregon Health Science University

They found

that low dietary intake of vitamin

blood pressure. The most comprehensive of these

shown above

Dr.

had no

effect.

Koh from the Alcorn State

University reported that

C was able to lower the blood 23 women with slightly elevated

a dietary supplementation of one gram of vitamin

pressure

in

his patients.

He had

investigated

blood pressure between 140-160 (diastolic value).

Remarkably,

diastolic pressure, the

disease. Vitamin

mm

64%

Hg

(systolic value)

of the

more important value

C supplementation

women were for

and 90-100

mm

Hg

able to lower their

decreasing the

risk for

heart

lowered the systolic as well as the diastolic

pressure on average by more than 5%.

Another important nutrient which

is

able to lower high blood pressure

is

magnesium, which functions as Nature's calcium blocker. Patients with high

among my readers should immediately supplement magnesium and other essential nutrients recommended

blood pressure

their diet with

vitamin C,

in this

Further Information: Vitamin C:

1984. Magnesium: Turlapaty

book.

McCarron DA 1984; Salonen JT 1987; Koh ET 1980; Iseri LT 1984.

PDMV

114

VITAMIN C DECREASES THE CARDIOVASCULAR RISK FROM EXTERNAL RISK FACTORS

Until

now we have discussed

C and

the beneficial role of vitamin

other essential

nutrients for decreasing mostly inherited or internal risk factors for cardiovascular

Vitamins,

disease.

Smoking Smoking

in

particular vitamin C, also neutralize

most external

cigarettes dramatically increases the risk for cardiovascular disease.

smoke contains an abundant amount

Cigarette

of free radicals.

We

these free radicals destroy vitamin

smokers deplete

their

By ceasing

to

body pool

C and

wall.

that

Moreover,

other antioxidant vitamins. Thus chronic

of antioxidant vitamins

smoke and by resupplemention

carotene smokers can greatly reduce the

know

already

these aggressive molecules have a toxic effect on the blood vessel

person.

risk factors.

much

faster than a normal

vitamin C, vitamin E, and beta

cardiovascular disease.

risk for

Stress Chronic stress increases the

risk for

cardiovascular disease.

How does

this

happen?

Physical or emotional stress increases the production of adrenalin molecules

For every molecule of adrenalin produced, one molecule of vitamin

body.

destroyed.

Thus, long term stress destroys

many molecules

C

of vitamin

and,

in

the

C if

is

not

resupplemented, depletes the body pool of vitamin C. It is not stress itself that causes cardiovascular disease, but the chronic vitamin C depletion in the body and the blood vessels which occurs during chronic stress.

Unhealthy Diet High

fat dietary

fat

molecules need

through our body. For every molecule of cholesterol processed, of vitamin

C

reactions.

Similarly, high levels of triglycerides

is

destroyed

-

depletion of the body's vitamin risk for

Once taken

habits can increase the risk for cardiovascular disease.

up by meals, cholesterol, triglycerides and other

used up as

C

pool.

fuel in

Thus,

it

be processed

at least

fats lead to

not the diet

itself

an accelerated

that increases the

cardiovascular disease, but the systematic depletion of vitamin

fuel vitamins in the

one molecule

metabolic converter (enzymatic)

and other is

to

C and

other

body.

Further Information: Smoking: Smith JL 1987. Adrenalin: Levine Ginter E 1974. Triglycerides: Sokoloff B 1966.

M

1986. Cholesterol:

115

Birth Control Pill

Women

taking

birth

control

cardiovascular diseases. that certain

C

vitamin

this

hormones and hormonal

pool.

Not the

over years greatly increase their

pills

How can

pill

itself

pool increases risk for cardiovascular disease taking hormonal birth control

should immediately greatly

Diuretic

risk to

or

if

these women.

If

you are presently

you have been taking them

in

the past you

develop cardiovascular disease.

Drugs

Taking diuretic drugs can increase your

risk for

vitamins and other essential

drugs should always be sure nutrients

to

have a

in their diet

the

not only water but

disappear.

nutrients

resupplemented, a chronic vitamin deficiency develops.

and other essential

is

accumulated water. With the

rid of

increased excretion of water through the kidneys into the urine also water-soluble

What

cardiovascular disease.

explanation? Diuretic drugs help the body to get

diuretic

body

of the vitamin

resupplement your vitamin body pool. By doing so you

start to

decrease the

pills

but the depletion in

for

reduces the body's

birth control pills significantly

birth control

risk

Several studies have shown

be explained?

sufficient

resupplemention

(see also chapter

'

If

not

Thus, patients taking

heart failure'

,

of vitamins

Section

F).

Certain Other Drugs

Besides hormones and diuretic drugs, other medication can also lead

body pool

of vitamin

to

a decreased

other essential nutrients. This effect can be explained

in

After taking a chemical drug, the liver has to detoxify these

part as follows.

substances.

C and

This form of 'chemical waste'

removal involves metabolic converters

(enzymes) and other biochemical processes which use up vitamin C and other essential nutrients at a high rate.

One

of

these drugs

is

interferon.

Unfortunately, no

systematic screening has been carried out on the vitamin depleting effect of chemical drugs.

you have

to take

It

is

therefore safe to take additional vitamin supplements

Further Information: Birth Control

Review

in:

whenever

chemical drugs.

Halliwell

Pill:

Briggs

B 1985; Burns JJ 1987.

M

1972; Rivers

JM

1975. Detoxification:

116

Blood Dialysis Patients with kidney failure must have their blood detoxified regularly.

so

their

blood

is filtered

through fine

molecules that have accumulated

molecules disappear

in

this

in

membranes which the blood.

help to get

rid of

In

Unfortunately, not only the small toxic

process, but the small beneficial molecules such as

vitamins and other essential nutrients are also

lost.

This explains

why

undergoing chronic dialysis frequently develop cardiovascular diseases kidney

their

Regular vitamin supplementation should decrease

failure.

prevent the development of cardiovascular disease

In

summary, the most

external risk factors vitamin

The

C and

figure

is

way make sure

effective to

order to do

the small toxic

to

in

in

this risk

and

dialysis patients.

decrease your cardiovascular

that your

patients

addition to

risk

from

body gets an optimum amount

of

other essential nutrients.

on the following page summarizes how vitamin C supplementation

neutralizes the risk from the different external risk factors discussed on these

pages. Smoking, stress, a high clinical

these

risk factors;

however, the depletion

most important among them. these

fat diet, birth control pills, certain

other drugs and

procedures deplete your vitamin body pool. Many vitamins are depleted by

risk factors,

If

the vitamin

of vitamin

C body

C

pool

is is

the most frequent and the

depleted by one or more of

the risk for cardiovascular disease increases. Resupplementing

your vitamin body pool by an optimum dietary intake of nutritional supplements neutralizes these risk factors

and helps you

Further Information: Vitamin Depletion

From

to

prevent cardiovascular disease.

Dialysis:

Blumberg A 1983.

117

VITAMINS NEUTRALIZE EXTERNAL RISK FACTORS FOR CARDIOVASCULAR DISEASE

External Risk Factors

Decreasing Vitamin

Body Pool



Smoking



Stress



High Fat Diet



Birth Control



Diuretic





Pill

Drugs

Certain Other Drugs

Blood Dialysis

Vitamin Body Pool

118

NOTES

119

SECTION

F

HOW TO SUCCESSFULLY TREAT OTHER HEART CONDITIONS WITH NUTRITIONAL SUPPLEMENTS



Improve Quality



Reduce Risk



Protect Bypass Vessels After Coronary Bypass Surgery



Decrease Restenosis After Coronary Angioplasty



Successfully Treat Heart Failure



Successfully Treat Irregular Heartbeat (Arrhythmia)

for

of Life After a Heart Attack

Clogging After Angioplasty

120

WHAT ARE THE CONSEQUENCES OF A HEART ATTACK

Coronary Artery Completely Clogged

Dead Lead

Dead Heart Muscle

Electrical Cells

Leads

to Irregular

In

previous sections

we have seen how

reduce the blood flow

A

suffocate.

to Insufficient

Blood Pumping

Heartbeat (Arrhythmia

in

heart attack

is

atherosclerotic deposits

in

coronary arteries

these arteries, thereby causing the heart muscle

caused by complete clogging

of

to

a coronary artery and by

the total cut-off of millions of heart muscle cells from oxygen and nutrition.

Two

severe consequences result from a heart attack.



If

the heart muscle cells are cut off from the blood circulation for several hours they

die

off.

muscle

As a

result,

25%

which

of

a certain portion of the heart muscle is

destroyed by a heart attack

becomes

is like

defunct.

A

heart

a four cylinder motor

running on three cylinders. •

In

a similar way, the electrical cells of the heart can be affected by a heart attack,

resulting

in

(arrhythmia).

grave forms

their

death or severe

Severe of

irritation

and leading

to irregular heart

electrical irritation (fibrillation of the heart

beat

chamber) and other

arrhythmia are the most frequent causes of death after a heart

attack.

The

larger the size of the

pumping, the greater the heart attack.

dead heart muscle, the greater the impairment of blood arrhythmias and the less likelihood of surviving a

risk for

121

HOW TO IMPROVE THE

QUALITY OF LIFE

AFTER A HEART ATTACK Stop and Reverse Deposits in Coronary Arteries With

C



Vitamin



Vitamin E



Beta Carotene



L-Proline



L-Lysine

Optimize Function

of

Suffocating Heart Muscle Cells

C



Vitamin



Carnitine







Coenzyme Q10 B -Vitamins Minerals and Trace Elements

Anybody suffering a heart attack should immediately contact a hospital and get emergency care. The sooner you obtain the proper medical attention, the greater the chances If

of limiting lasting

damage to your heart muscle cells. Every minute counts. some time ago, you should continue to consult

a heart attack has occurred

regularly with your physician.

about how

It

is

to

In

addition, this

improve the quality of your

life

page

after

will

give you valuable information

a heart attack.

important to understand that once a heart attack has led to the death of heart

muscle

cells,

these cells seldom regenerate. Therefore, the primary aims after a heart

attack are the following:

Halting the further growth of atherosclerotic deposits

in

the coronary arteries and

thereby preventing the reoccurrence of a heart attack. The essential nutrients

for

achieving this aim are vitamin C, other antioxidant vitamins, as well as the amino acids lysine and proline.

Optimizing the function of those heart muscle cells which are essential nutrients for achieving this aim are carnitine,

other

B

vitamins,

magnesium, as

well as other minerals

still

coenzyme Q10.

alive.

The

panthetine.

and trace elements.

122

WHAT

IS

A CORONARY ARTERY BYPASS

Bypass Blood Vessel

Coronary Artery

Blood Bypasses Deposits and Guarantees Nourishment of Heart Muscle

A

coronary bypass operation becomes necessary

if

one or more coronary

have developed severe atherosclerotic deposits which threaten

and

to

cause a heart

attack.

In

arteries

to clog the arteries

order to avoid a heart attack, a blood bypass

constructed surgically which guarantees the blood flow to

all

is

parts of the heart

muscle.

During bypass surgery usually a vein

is

bypass blood vessel. Generally, one end

taken from the leg and reimplanted as a of this

the other end to the coronary artery further In this

way, the atherosclerotic deposits

in

bypass

down on

is

attached to the aorta and

the outside of the heart muscle.

the coronary artery are bypassed and the

blood flow through the bypass blood vessel guarantees optimum blood supply

proper function of the heart muscle.

for the

123

WHAT ARE THE MAIN PROBLEMS AFTER CORONARY BYPASS SURGERY Risk of Blood Flow Interruption in





Blood Clot Formation

in

Bypass Blood Vessel

overall

success

of

in

a coronary bypass operation

problems: blood clots and atherosclerotic deposits •

Problem number one: a blood blood flow through them.

clot

forms

in

in

Bypass Blood Vessel

is

threatened by two main

the bypass blood vessels.

the bypass blood vessels, cutting off the

This complication occurs shortly after the operation,

generally within hours or a few days.

If

untreated, this blood clot

the blood flow through the bypass blood vessel and thereby

off

by:

Atherosclerotic Deposits

Form

The

Bypass Blood Vessel

will

completely cut

make

the previous

operation ineffective. •

Problem number two: atherosclerotic deposits develop inside the blood vessel. vessels for

is

The development

of atherosclerotic deposits

a long term process. Generally,

these deposits to develop.

coronary arteries, the deposits

it

in

takes several months or several years

Similar to the atherosclerotic deposits in

bypass bypass blood

wall of the

in

the regular

the bypass blood vessel can lead to a decreased

blood flow and eventually to clogging.

The consequences

in

each case are the same: an

through the bypass blood vessels and an increased

interruption of the blood flow risk for

a heart attack. Keeping

the bypass blood vessels patent avoids further bypass operations

The

following

you

to

page summarizes the most important

achieve

this aim.

nutritional

and heart attacks.

supplements which help

.

124

HOW TO IMPROVE QUALITY OF

LIFE

AFTER CORONARY BYPASS SURGERY Protect Your Bypass Blood Vessels With the Help of



Vitamins Preventing Blood Clot Formation •

Vitamin C



Vitamin E

Beta Carotene





Vitamins and Natural Amino Acids Preventing Development

Deposits

of Atherosclerotic •

Vitamin



C

Other Antioxidant Vitamins



Lysine



Proline

There are several ways

which

in

nutritional

supplements help

bypass blood vessels and thereby improve the •

Preventing blood clot formation

carotene have

all

been shown

formation of blood clots.

In

in

to

quality of

C

,

to maintain healthy

after

bypass surgery:

bypass vessels: vitamin C, vitamin E and beta

have important properties which help

addition, vitamin

C

dissolve blood clots once they have been formed. vitamin

life

to

prevent

has also been shown

to help

These important properties

vitamin E, and beta carotene should be utilized routinely

in

of

minimizing

the complications of blood clot formation after coronary bypass and other surgeries. •

in bypass blood vessels: atherosclerotic venous bypass vessels closely resemble the deposits in normal Lipoprotein(a) again, plays a critical role in the development of these

Preventing atherosclerotic deposits deposits arteries.

in

bypass deposits. Thus, the vitamins and other essential nutrients recommended for the

treatment of atherosclerotic deposits are also beneficial for preventing

development

of the deposits in

them are vitamin C, vitamin

A

note for those

E,

bypass blood vessels. The most important among

beta carotene, L-lysine and L-proline.

among my readers who

are taking blood-thinning medication:

The

optimum

flow

vitamins mentioned above have a natural effect of keeping your blood condition (viscosity).

They may,

therefore,

enhance the

in

effect of your blood thinning

medication. Ask your doctor about additional controls and take your vitamins as regularly as

you take other medication.

Further Information: Anti-clotting effect: Bordia

Kojima S

1

986; Salonen JT

1

991

AK 1979 and

1985; Beetens J 1986;

125

WHAT

CORONARY ANGIOPLASTY

IS

Coronary bypass surgery approach

more

to

new blood

methods. For

flat to

is

this

purpose a catheter

and moved forward through the aorta

coronary artery close to the deposits. At catheter

vessel pipeline for optimum blood

contrast, coronary angioplasty

In

the 'rotor rooter'

is

remove atherosclerotic deposits mechanically by means

recently, by scraping

leg artery

a

installs

supply to the heart muscle.

a balloon

tip

However, complications occur

tip of

in

this

the

In

many cases

the blood flow through the

procedure.

one out

of three patients

The nature

.

of

directly related to the fact that angioplasty necessarily

mechanical damage

or,

reaches the

normally a balloon at the

this point

the wall of the coronary arteries.

coronary artery can be improved by

is

the catheter

until

of

inserted into the

pressure which squeezes the atherosclerotic deposits

inflated with high

complications

is

to the inside of the

these

causes

blood vessel wall. The most frequent

complications are blood clot formation and rapid grow of

new

deposits at the

same

location as before (restenosis).

What

factors influence the rate of restenosis after angioplasty?

that lipoprotein(a)

is

nature's top repair molecule

and

it

is

high lipoprotein(a) levels are a leading cause for restenosis.

colleagues from Emory University lipoprotein(a) blood levels

in

We

already

know

therefore no surprise that Dr.

Hearn and

his

Atlanta found that angioplasty patients with

above 19 mg/dl had a

fivefold greater risk for restenosis

than those patients below this margin. For patients with lipoprotein(a) levels above 40

mg/dl the restenosis

Thus,

for patients

risk after

who have

angioplasty

to

was more than

undergo angioplasty, the

ten fold higher.

recommendations

of this

book.

Further Information: Hearn

JA 1992.

success rate can be and by following the

overall

greatly reduced by neutralizing the risk from lipoprotein(a)

126

Angioplasty to

Figure

Is

a Mechanical Procedure

Improve Blood Flow

to Suffocating

A

Heart Muscle

Balloon Catheter "Inserted

in

Is

Leg Artery

Deflated Catheter Tip

Reaches Coronary

Deposits

Artery

in

Coronary Arteries Reduce Blood Flow

Figure B

Inflated Balloon

Catheter

Squeezes Deposits Coronary Arteries Vessel Wall

is

in

Flat

-

Injured

During This Procedure

Success Rate

70%

of This

Procedure:

Get Improved Heart Muscle

of Patients

Blood Flow

to

30% Have

Complications

-

Requiring Repetition of Procedure or

Coronary Bypass Operation

127

HOW TO IMPROVE THE SUCCESS RATE AFTER ANGIOPLASTY Vitamin Supplementation Overall

Success Rate

Can Improve Angioplasty

of

After Successful

Ideally,

Balloon

Catheterization Atherosclerotic

Deposits Are Reduced

The Following

Nutritional

Supplements

Can Improve Long-Term Success:

The

Vitamin



Vitamin E



L-Lysine



L-Proline

needed to minimize restenosis after angioplasty are much the the recommendations for blood vessel protection in general. During and

essential nutrients

same as

after angioplasty the •

C



Vitamin

C

achieve the following therapeutic effects:

accelerates healing of the blood vessel lesion by collagen formation



Vitamin E gives important antioxidant protection



Vitamin C, vitamin E, and beta carotene decrease the



Lysine and proline help to neutralize the risk from lipoprotein(a)

Vitamin E has already been

shown

to

risk for

blood clot formation

prevent restenosis after angioplasty. 115

patients undergoing coronary angioplasty

were studied. Half

of

these patients

received 1,200 International Units of vitamin E per day; the other half received an

months the rate of restenosis of the coronary arteries was compared between the two groups. The patients receiving vitamin E had a much less inactive placebo. After four

restenosis than those patients without vitamin E.

Any

among my readers who

patient

immediately

start to

before, during,

and

how

about

to

after angioplasty with nutritional

the overall success of this procedure.

describe

is

undergo angioplasty should

take nutritional supplements. By protecting your blood vessels

In

supplements you can maximize

the remaining part of this section

I

will

patients with other heart conditions can benefit from taking nutritional

supplements. Further Information:

DeMaio SJ 1992.

128

WHAT CAUSES HEART FAILURE Deficiency of Fuel Nutrients

In

Heart Muscle Cells Causes Heart Failure

/*

Cell Fuel Nutrients

Vitamin

C

Carnitine

Coenzyme Q10 Vitamin B1,B2,B3,B5,B6,B12 Minerals

& Trace Elements

Optimum Blood Pumping: Less Edema • Less Shortness •

of •

Breath

Less Fatigue Nutritional

Leads

to

Impairs Contraction of

Muscle Cells

Heart Muscle Cells

of Heart

Heart failure

pumping

is

Nutritional Deficiency

Resupplementation

Optimum Contraction

a disease caused by weakness

of the heart

attack or

in

patients with

high blood pressure.

Heart failure can also occur

spontaneously without any previous heart condition. The of heart failure

muscle

In

muscle which impairs the

of blood into the circulation. Heart failure frequently develops after a heart

is

common

underlying cause

the same: an exertion of the heart muscle and a depletion of heart

cells in vitamins

and other

cell fuel nutrients.

patients with heart failure millions of heart muscle cells suffocate from a lack of

essential nutritional fuel. This cell fuel reactions

in

each

cell.

A

is

needed

heart without cell fuel

work properly. Heart muscles lacking essential properly

.

is like

thousands

of oil

biochemical -

it

does not

fuel nutrients are not able to contract

As a consequence, the heart muscle does

body's circulation.

for

a motor without

not

pump enough

blood into the

129

HEART FAILURE CAUSES IMPAIRED BLOOD PUMPING

The

figure

on the following page summarizes the consequences

of

a vitamin deficient

heart muscle for the body of the patient.

Figure A: Instead of one cup which leaves the heart normally with every heart beat, half

a cup of blood or even less

blood

is

nutrients.

too

little

will

be ejected

into the circulation.

This amount of

supply the various organs of the body with oxygen and

to

As a consequence, shortness

of breath,

water retention (edema) and

general weakness occur.

Figure B:

an optimum dietary intake

contrast,

In

of essential fuel nutrients for the

heart muscle cells optimizes the contraction of every heart muscle regains

The

different

patient

organs

can enjoy a

its

strength and

of the

life

hardly known.

In

As a

result, the

whole

body receive adequate oxygen and nutrients and the

is

frequently caused by vitamin deficiencies

today's medical text books the causes of heart failure are

described as largely unknown. The understanding

cell.

sufficient blood into the circulation.

without major restraints.

Unfortunately, the fact that heart failure is

pumps

for millions of heart failure

consequences of patients are shown on the fatal

this

insufficient

following pages.

130

Figure A:

Heart Failure



Shortness



Edema



Fatigue

of

Weak of

Contraction

Weak Pumping

Heart Muscle Cells

of Heart

Heart

Breath

Pumps Only About

Half a

Teacup

of

Blood

With Every Heartbeat

Figure B:

Healthy Heart

Optimum Blood Supply

Maximum of

Contraction

Heart Muscle Cells

Optimum Pumping of

Heart

to All

Organs

of the

Body

Heart Pumps One Teacup of Blood

With Every Heartbeat

131

THE HEART FAILURE EPIDEMIC

Heart Failure Disease Tripled

Number

in

Recent Decades

of

9

15

Mill

Heart Failure

Patients

^^-^^

5 Million

#

H

1

1950

In

1

1970

recent years heart failure has spread

like

1985

an epidemic.

In

the western industrialized

countries, about 15 million people suffer from heart failure today. During recent

decades the number this

of heart failure patients

who had

to

be hospitalized because

of

disease increased threefold.

Equally alarming

is

the short

life

expectancy

heart failure.

Further Information: Packer

M

1987.

of patients

once they are diagnosed with

132

HEART FAILURE PATIENTS HAVE A SHORT LIFE EXPECTANCY With Conventional Treatment Alone

One Out

100% Percentage

of

Two

Heart Failure Patients Dies Within Five Years

"

Average Death Rate

of

Patients Alive

50%

-High Death Rate for Patients

With

Heart Failure

1-

1

Year

1

5 Years

10 Years

Survival

Time

Patients with heart failure have a very unfavorable prognosis: •

One



For

out of two patients dies within the

diagnosed.

many

ten years only

After

one

or

first five

years after the heart failure

two patients out

of ten are

alive.

heart failure patients a heart transplant operation remains the only hope.

Both, the epidemic proportion of heart failure (previous page) of this

still

is

disease

that vitamin deficiencies are not yet of this disease.

and the bad prognosis

page) are no coincidence. They are the direct result of the fact

(this

known and understood as

the underlying cause

Consequently, no effective treatment has been available.

Those among my readers who are candidates

for

a heart transplant operation

may be who

interested to read the testimonial of a former heart transplant candidate (G.P.)

started to follow

my

cardiovascular recommendations. By

refilling

his suffocating

heart cells with vitamins and other essential nutrients his heart performance greatly

improved.

now

On

He was

able to cancel the scheduled heart transplant operation and he

leading a normal

life.

page we

will

the next

see that the conventional medical treatment

leads to a vicious cycle which

Further Information:

is

Mc Kee PA

of heart failure

responsible for the bad prognosis of this disease.

1971

is

133

THE FATAL CONSEQUENCES OF INCOMPLETE TREATMENT OF HEART FAILURE

Heart failure leads to water accumulation (edema) of the body.

To remove accumulated water from

to take diuretic drugs.

which

is

explained

the legs, lungs, and other parts

At this point of the treatment the patient enters a vicious cycle the adjacent figure.

in

in

the body heart failure patients have

The understanding

clue to the successful treatment of heart failure disease

in

of this vicious cycle is

a

the future.

Nutritional deficiencies of the heart muscle cells lead to a weak pumping of the heart. The low blood output into the arteries results in low blood pressure, which has direct consequences for the proper function of the kidneys. The primary role of the kidneys With low blood pressure, less water is filtered out is to filter body water into urine. accumulates in the legs and other parts and, instead of leaving the body via urine, of the body. As a result, edema occur in the feet and legs as well as in the lungs, where leads to shortness of breath and eventually, to lung edema. it

it

In

order to eliminate the abundant body water and to provide

diuretic medication of the

On one

given.

is

relief to

side, this medication increases the

the patient

filter

function

kidneys and flushes out the body water into the urine. Unfortunately, diuretic

drugs also flush out the small vitamins and other essential nutrients

The body's

into the urine.

loss of essential nutrients further aggravates the lack of fuel nutrients for

the heart muscle cells, hereby further aggravating the heart failure.

A

vicious cycle

begins.

A weakened

heart leads to even

dosages

of diuretic

medication

nutrients

and

weakening the

further

is

more water accumulation

required, further depleting the heart.

We

has such a poor prognosis and why there than to receive a

new

heart

-

in

is

the body. Higher

body

of essential

suddenly understand why heart

no other alternative

for

many

failure

patients

or to die before a suitable donor heart can be found.

134

The Vicious Cycle

of

Conventional Heart Failure Treatment

Without the Use of Nutritional Supplements

Nutritional

Low Blood

Deficiency

Pressure

Weakness

of

Heart Muscle

($H

Weaker Heart Increased Nutritional

Impaired Filtering of

Deficiency of Heart

\

Muscle Cells

/>

Body Water from Kidneys

Further

to Urine

Water Retention

/ More

Diuretics

Water Retention • Edema in Legs

Flushing Out of Vitamins

and Other Essential Nutrients

in

Urine



Diuretic Medication

Shortness

of

in

Body:

Breath

135

HOW VITAMINS CAN INTERRUPT THE VICIOUS CYCLE OF HEART FAILURE The Basic Heart

Failure Therapy:

Resupplement Vitamins and Other Essential Nutrients

I Resupplement

Stop Weakness of Heart Muscle

Essential Nutrients

Optimum

Level of

Vitamin Body Pool

l Vicious Stop Depletion of Vitamins

Cycle Stop Water Retention

Stopped

Less or No Diuretic Medication

With this page In

I

am

addressing

my

colleagues

the attempt to help our patients

we have

While improving the immediate problems

in clinical

medicine:

learned to prescribe diuretic medication.

for the patient, the

water accumulation

in

the

body, diuretic medication depletes the patient's body of water soluble vitamins and

thereby starts a vicious cycle. While diuretic medication

may

still

be needed

in

severe

cases, no one should prescribe diuretic drugs any longer without alerting the patients to

resupplement

bodies with vitamins and essential nutrients.

their

Patients and doctors should be equally interested

heart failure with an nutrients

Vitamin

in

the diet.

optimum supplementation

in

interrupting the vicious cycle of

of vitamins

and other essential

Most important among these essential nutrients

are:

C

Carnitine

Coenzyme Q10 B vitamins Minerals and trace elements

The

following

pages

essential vitamins

will

highlight

and nutrients

in

some

of the clinical

evidence

the treatment of heart failure.

for the

importance

of

136

CARDIOMYOPATHIES ARE PRIMARILY CAUSED BY VITAMIN DEFICIENCY

Cardiomyopathy



Weakness Leading

to

is

a

Muscle

of the Heart

Heart Failure

Cardiomyopathies Are



Primarily

Caused by

Vitamin Deficiencies of Millions of Heart

Muscle Cells

Resupplementation



of

Essential Nutrients

Can Prevent and Treat Cardiomyopathies

The best documented form of heart failure in which vitamins and other essential nutrients were proven to be most effective are cardiomyopathies. What are cardiomyopathies? The Latin word cardiomyopathy means 'disease of the heart muscle'. The unique feature of this form of heart failure is that occurs frequently without any other heart condition being present. This fact makes cardiomyopathy an it

ideal

disease

document an

to identify the underlying

problem

of heart failure in general

and

to

effective treatment for this disease.

to the current medical textbooks the causes for cardiomyopathy are still unknown. However, during recent years scientific evidence showed that cardiomyopathy is primarily a vitamin deficiency disease. Dr. Karl Folkers and his colleagues from the University of Austin, Texas, are pioneers of cardiomyopathy research and nutrition. They have shown that coenzyme Q10 (ubiquinon), an

According largely

important

cell fuel nutrient, greatly

Dr. Folkers recently

review included 25 Japanese institutions.

70%

improved the health

reviewed the available

The summary

of the patients with

clinical

clinical reports

of ten

years of

clinical

cardiomyopathy patients.

coenzyme Q10. This

from 110 physicians

in

41

medical

research showed that an average of

cardiomyopathy and heart

failure benefited

supplementation of coenzyme Q10.

Further Information: Folkers

of

studies of

K 1985; Mortensen SA 1990.

from a dietary

137

COENZYME Q10 BENEFITS PATIENTS WITH HEART FAILURE Coenzyme Q10 Improves

Heart Pumping Function

Heart

Pumping Function

30% Improved

Heart Performance

i%

200 Improved

Before

XZZZA

During

IZZI

CoQ10 Therapy

Normal

Severe

Moderate

Heart

Heart Failure

Heart Failure

Stage

Coenzyme Q10

(ubiquinon),

plants or bioenergy centers 'breathing' of our cells.

is

a

in

Heart Failure

of

critical fuel for

each

cell of

the functioning of the miniature

our body.

It

is

power

essential for the proper

was found to be much lower in the blood and compared to healthy persons.

Coenzyme Q1

in

the heart muscle of patients with heart disease

The

figure

and

their colleagues.

above summarizes the

heart failure.

In this

mg of coenzyme Q1 per day to 88 patients with more than 75% of these patients showed a significant

They gave study

results from a study by Dr. Langsjoen, Dr. Folkers

1

00

pumping function

improvement

in

The

improvements were observed



following

the

of their heart

In

coenzyme Q10: coenzyme increased more than

of taking

function of these patients

general the more severe the heart

the benefit from taking •

few weeks

their overall well being.

Patients with very severe forms of heart failure benefited the most from

Q10 supplementation. The pumping 200% while taking coenzyme Q10. •

after

as well as

Coenzyme Q10 had no

failure condition in a patient, the greater

coenzyme Q10. side effects.

Further Information: Langesjoen

PH

1988: Mortensen

SA

1990.

was

138

COENZYME Q10 PROLONGS THE LIFE OF PATIENTS WITH HEART FAILURE Coenzyme Q10 Saved Two Out

All

Three Patient Lives

Patients

Study

at Start of

=

of

WithCoQIO

100%

75%

of Patients

Still

Co Q10

Without

Only

25% Still

Year

1

More

recently the

studies with

same group

coenzyme Q10

in

of Patients

Alive



of doctors published the long-term results of their

heart failure patients.

By now they had followed 137

The reported

In

health benefits

are very encouraging:

After three years, three out of four heart failure patients taking still



Q10

3 Years

2 Years

patients with heart failure over a period of three years.

from coenzyme

Alive

coenzyme Q1

were

alive.

contrast,

when

heart failure patients received only conventional drugs only

out of four patients

Thus, the

measure

life

of

of

was

alive after three years.

every second patient with heart failure could be saved by the simple

supplementing the

improvement

diet with

and the the heart muscle

of the survival rate

lack of

coenzyme Q10

These

scientists

significantly

still

one

in

coenzyme Q10. quality of cells is

conclude that coenzyme

improves the survival rate

Further Information: Langsjoen

PH

Q10

life

Moreover, the dramatic

of the patients

an important cause constitutes the

of patients with heart failure.

1990.

shows

that a

for heart failure.

first

therapy that

139

THE HEART MUSCLE CELLS MORE SEVERE HEART FAILURE

LESS CARNITINE

IN

Carnitine Deficiency Parallels Heart

Pumping Weakness

I

Normal

Carnitine

Carnitine

Deficiency

Severe Carnitine

Levels

Deficiency

T

Carnitine Levels in

Heart Muscle

Severe Healthy Heart

Heart Failure

Another important nutrient which a natural amino acid.

carnitine,

Its

Carnitine also

removes useless

frequently deficient

is

main

by transporting energy molecules

Heart Failure

role

to

in

heart failure patients

improve the energy

is

level of the cell

power plants of each cell. from the power plants inside each cell (waste

(fatty

fuel

is

acids) to the

removal) and thereby helps to improve their function.

Low

levels of carnitine lead to

consequently

to

carried out by

my

carnitine

in

colleagues at the

of the cellular

the heart muscle.

in

small pieces of heart muscle routinely taken from heart failure patients for

diagnostic purposes.



power plants and An important study was German Heart Center in Berlin. They measured

an impaired function

a low energy level

The highest

The

following significant findings

levels of carnitine

were found

in

were made

study:

in this

the heart muscle cells of healthy

hearts. •

The weaker the heart function of the measured in the heart muscle cells.

Thus, carnitine deficiency

was found

heart failure.

Further Information: Regitz

V 1990.

to

patient, the lower the

be closely related

to the

amount

degree

of carnitine

of severity of

140

CARNITINE BENEFITS HEART FAILURE PATIENTS Carnitine Supplementation Improves Heart Failure

1

Decrease

.

of

Edema

(Less Water Accumulation

and Other Parts

of the

2.

Less Shortness

3.

Less Need

for

of

Legs

in

Body)

Without Carnitine

OCD

Drugs in

Half)

Digitalis

Tablets^

CD With Carnitine

Without Carnitine

Since carnitine deficiency heart failure,

it

is

With Carnitine

Breath During Exercise

Medication Cut

(Digitalis

Symptoms

is

obviously an important factor for the development of

no surprise that dietary carnitine supplementation greatly benefits

patients with heart failure.

Dr. Ghidini all

of

and

his

whom were

colleagues from Verona,

Italy,

conducted a study with 38 patients,

The physicians gave two grams of 45 days and compared the performance

suffering from heart failure.

carnitine to half of the patients for

40

to

their heart to the other half of the patient group,

who

did not receive carnitine.

patients continued their conventional therapy, including digitalis medication. patients receiving additional carnitine function.

showed remarkable improvement

L-

of All

The

of their heart

Patients receiving carnitine had:



Less water accumulation



An increased

in their

bodies (less edema)

natural water excretion from their bodies



Less shortness



A



Taking carnitine was safe and no side effects were observed.

of breath

normalized heart beat

rate.

As a consequence

of

conventional drugs

(digitalis) in half.

these remarkable improvements, the patients could cut their

The physicians noted

that L-carnitine treatment

also reduced the blood levels of cholesterol and triglycerides

Further Information: Ghidini

O

1988.

in

the patients" blood.

141

TESTIMONIALS FROM PATIENTS WITH HEART FAILURE WHO ARE FOLLOWING MY

CARDIOVASCULAR HEALTH

RECOMMENDATIONS

Dear

Dr. Rath:

am happy to report that your cardiovascular health recommendations have improved my life! Now can climb the stairs readily and without shortness of I

I

breath.

I

can also resume hiking

exhausted.

I

for 3-4 miles

a day without feeling

do have an energetic outlook towards

life,

and

I

tired

am

and

sure

it's

due to your recommendations. Thank you very much for all the research you have done and are continuing to

do

for

people with circulatory problems.

Yours

truly,

A.G.,

USA

Dear I

Dr. Rath:

am 64

years old and

for four

years have been suffering from heart

arrhythmia, and shortness of breath.

while walking

I

had

to

pause

I

had

difficulty in

frequently.

I

have been following your

cardiovascular health recommendations for the past two

remarkable changes:

I

can climb

walk one mile or more, even yards.

I

have more energy

stairs without

uphill.

Before,

I

weeks and

any problems.

had

to

pause

after

I

I

notice

can now

about 200

for living.

Because of my health improvements my physician showed recommendations for cardiovascular health. G.W., Germany

failure,

climbing stairs, and

interest

in

your

142

Dear I

Dr. Rath:

would

like to

inform you about two patients to

whom

have applied your

I

cardiovascular health recommendations during the past few weeks. H. K.

a patient with coronary heart disease. A few months ago he began

to

increasing shortness of breath and frequent angina pectoris attacks.

a severe angina pectoris attack, the patient had to be admitted hospital

in

a life-threatening condition.

stay, his condition

During the

became even worse.

fifth

week

After to the

of his hospital

With heart failure and severe

arrhythmia the patient had to be transferred to the intensive care unit received several drugs to treat the angina pectoris symptoms. half

months the

When

the morning hours.

After two

was discharged from the hospital. Angina occur with minimum exertion, and particularly

patient

pectoris attacks continued to in

for

During the entire duration of his hospital stay the patient

several days.

and a

is

have

discharging the patient the clinician gave a very

unfavorable prognosis with respect to the

life

expectancy

of the patient.

medication consisted of nitrates, calcium antagonists,

digitalis,

His

and a

diuretic drug.

A few days

after leaving the hospital the patient started to follow your

cardiovascular health recommendations

By doing

so. a gradual

health as well as

walk up

The

to

in

his general condition.

one hour, even

patient

is

in

addition to his other medications.

improvement occurred uphill,

In

in

the patient's cardiovascular

the meantime, the patient can

without significant shortness of breath.

following his regular daily activities without

help from outside.

general, the patient

In

any

became more

restraints or

mobile,

more

secure, less dependent, and because of that, more confident with respect to his future

remarkable

life

The second case

improvement

history

of cardiac failure in

was

irregular.

improvement

is

document

Further tests are planned to

expectancy.

clinical

the report of a

woman who

connection with a severe

developed symptoms

viral infection.

The heartbeat

By following your cardiovascular recommendations a rapid in

the

patient's

health

began. After two months the

cardiovascular functions had stabilized, and the heartbeat

Moreover, the patient became more active again and she carry out her daily activities

in

house and garden without

cardiovascular health recommendations I

the

of the patient.

will

is

was regular. now able to

difficulty.

Your

be continued.

wish you further success with the cardiovascular recommendations you

developed.

J.K.. M.D..

Germany

143

HEART FAILURE CAN BE ERADICATED Our present knowledge treatment of heart failure

Heart failure



primarily

is

vitamin deficiency e.g. after

function

causes as well as the prevention and the can be summarized as follows:

of the

is

caused by vitamin

deficiencies.

the direct cause of heart failure.

In

In

many cases other cases,

a heart attack, vitamin deficiencies further impair heart muscle

and aggravate heart

failure.

Optimum supplementation with vitamins and other essential nutrients measure for prevention and treatment of heart failure.



is

the basic

Any treatment



need



of heart failure with diuretic

for vitamin

supplementation

encourage my colleagues

I

in

drugs greatly increases the

for the patient.

clinical

medicine

to help

information as soon as possible for the benefit of your

thousands

own

spread

this

patients

and

of other patients.

A

special note

is in



You should

start

order for heart failure patients

among my

readers:

immediately to supplement your diet with vitamins and

other essential nutrients.



While following the recommendations

of this

book, do not discontinue

your regular medication without consulting your doctor.



Share your health improvements with your doctor.

make

We now

Together you can

the best decisions to reduce your regular medication.

turn to another frequent heart diseases which

is

essentially preventable.

144

WHAT CAUSES IRREGULAR HEARTBEAT Figure A:

Optimum Function

Leads

of Electrical Cells

to

Regular Heart Beat

Currently eight million Americans suffer from irregular heartbeat (arrhythmia).

Arrhythmia

is

caused by vitamin deficiencies

primarily

can be prevented by optimum intake

The

electrical

impulse responsible

the heart (sinus node). "wire" of cells electricity.

in

of the electrical heart cells

and

of essential nutrients.

for the

heartbeat

is

generated

This impulse of biological electricity

is

in

the battery cells of

transported through a

the middle of the heart which are specialized for transporting

Eventually this electrical impulse reaches millions of heart muscle cells

and stimulates them

to contract for the heart beat.

transport of biological electricity

in

the heart

is

The proper generation and

responsible for a coordinated

contraction of the heart muscle and for a regular heartbeat.

The generation and transport of the on optimum supply of the electrical If

electricity

needed

cells with vitamins

for regular

heartbeat depends

and other essential

nutrients.

these electrical cells do not receive an optimum amount of these fuel nutrients,

either the generation of the electrical impulse or the transport of the electricity

disturbed or interrupted.

Thus, the lack of

can be

fuel nutrients in the electrical cells of the

heart causes irregular heart beat and arrhythmia.

145

THE BASIC TREATMENT OF IRREGULAR HEARTBEAT Resupplementation

of Cell Fuel Nutrients

Normalizes Heartbeat

Cell Fuel Nutrients

C



Vitamin



Carnitine



Coenzyme Q10



Vitamin B1,B2,B3,B5,B6,B12



Magnesium



Other Minerals & Trace Elements

-C Vitamin Deficiency

Vitamin deficiency

Heartbeat

Supplementation With Fuel Nutrients

Impairs Function of Electrical

Regular

Leads

Heart Cells

to

Optimum Function

of Electrical

and a lack

Heart Cells

of fuel nutrients in the electrical cells of the heart are

primary causes of irregular heart beat. Resupplementation of vitamins and other essential fuel nutrients

the diet

is

the basic therapeutic

measure

to

prevent and to

arrhythmias.

treat

As

in

for the

other muscle cells

in

important: vitamin C, carnitine,

the heart, the following fuel nutrients are particularly

coenzyme Q10,

other

B

vitamins,

magnesium, as

well

as other minerals and trace elements.

Some more

of the essential nutrients with antiarrhythmic properties will

detail

on the following pages.

be discussed

in

146

REDUCES IRREGULAR HEARTBEAT

MAGNESIUM

Magnesium Decreased

Number

Irregular Heartbeats

by 70 Percent

of

Irregular

70%

Heartbeats

Magnesium

Magnesium

one

is

of the essential

balance with calcium. Magnesium powerful agent

shown • •



to

in

is

body

salts

Administration

and

of particular

normalizing irregular heartbeat. Moreover,

improve different forms

importance

nature's physiologic calcium blocker

is

and

its

is

a

magnesium has been

of arrhythmias:

chambers (ventricular tachycardia) chamber (ventricular fibrillation) Irregular heartbeat originated in the smaller chambers of the heart situated above the main chambers (supraventricular arrhythmia) Rapid beating

of the heart

Fibrillation of the heart

shown above, Dr. Iseri and his colleagues from the University of showed that magnesium is able to lower the number of irregular heartbeats by more than 70%. Moreover, magnesium helped to normalize rapid heartbeats. In the studies mentioned above, magnesium was given to patients with severe forms of In

the clinical study

California

arrhythmia.

In

summary,

magnesium

-

nature's calcium antagonist-

irregular heartbeats

and arrhythmia.

Further Information:

Iseri

LT 1984 and 1986; Turlapaty

can reduce most forms

PDMV

1980.

of

147

CARNITINE REDUCES IRREGULAR HEARTBEAT

Carnitine

Number

Decreased

85 Percent

Irregular Heartbeat by

of Irregular

I

Heart Beats

-

%

85

I

Patients Taking

Patients Taking

Regular Medication

Regular Medication

+

Only

Additional Carnitine

The amino acid

reduces irregular heartbeat.

L-carnitine also

In

a

clinical

reported by Dr. P. Rizzon and his colleagues from the University of Bari, effect of carnitine

on reducing arrhythmias was studied

suffered a myocardial infarction.

in

patients

Arrhythmias are a frequent cause

of

study

Italy,

who had

the just

death after a

heart attack has occurred. Thus, the reduction of arrhythmias by use of carnitine can greatly increase the

In

the study

days during

numbers

85%

in

of

a patient to survive a heart attack.

the figure above, 28 patients received L-carnitine for several

their hospital stay.

of irregular heartbeats

During that time the heart beat

same

These remarkable

results with carnitine

carnitine

who

were achieved

in

the

had up

to

did not receive L-

acute therapy.

In

way, carnitine given as dietary supplement helps prevent and reduce

irregular heartbeat.

Further Information: Rizzon P 1989.

i

was recorded and

were counted. Patients receiving

less irregular heartbeats than those heart attack patients

carnitine.

the

shown

chance

148

TESTIMONIALS FROM ARRHYTHMIA PATIENTS

WHO ARE FOLLOWING MY CARDIOVASCULAR HEALTH RECOMMENDATIONS

Dear

Dr. Rath:

Two months

ago,

I

was experiencing loud heartbeats, tachycardia and saw my doctor who promptly put me on

irregular beating of the heart.

antiarrhythmic medication.

I

I

can honestly say

this

medication did

me

absolutely no good.

Because I've tried to investigate alternative treatments for my ailments (I've began to follow your had diabetes for 38 years) recommendations for cardiovascular health. What a smart decision that was! Within a few days, the tachycardia stopped and I've not experienced any loud or irregular heartbeats. It's like a miracle. It must be the combination of nutrients you suggest because had been taking I

I

Coenzyme Q10 know about the mention

my

regular vitamins.

benefits of your cardiovascular

during the diabetic seminars that

I

am

I

I

everyone

conducting. At the list

for

sending

me

a copy

of the letter

you sent

last

to Pres. Clinton,

V.P. Gore, and Hillary Clinton.

Because

of

USA

I

of the ingredients

I

Thank you

B.M.,

tell

recommendations and

handed out copies of your letter, with a your recommendations. hope you won't mind.

seminar in

it

separately from

your research, I'm able to continue working.

149

Dear

How

Dr. Rath,

after

delightful,

recommendations

irregular heartbeats,

your

following

for just

cardiovascular

and the freedom

to

breathe

freely.

restored as one has increased vigor and endurance.

spends All

less time thinking about their heart

this

by

simply

health

2 months, one notices the absence of

cardiovascular

recommendations, which have become the answer

is

a word, one

and more time enjoying

your

following

Confidence In

for

life.

health resolving

coronary problems.

I

am happy

to

have

this opportunity of

advanced medical research and recommendations J.S.,

Dear

expressing

for

my

gratitude for your

your cardiovascular health

.

USA

Dr. Rath:

Before following your cardiovascular health recommendations,

wake up with a pumping feeling Upon changing position, would it

even forget

J.A.,

USA

I

have a

heart.

I

in

my

stop.

feel better

I

used

to

chest, no pain, just discomfort. I

no longer have

now than ever

in

that problem.

my

life!

I

150

ARRHYTHMIAS CAN BE ERADICATED Our present knowledge of arrhythmias



of the

causes, the prevention, and the treatment

can be summarized as follows:

Arrhythmias are primarily caused by vitamin deficiencies electrical heart cells. In

cause

many cases

vitamin deficiency

of irregular heartbeat. In other cases, e.g. after

vitamin deficiencies can contribute to

life

is

of the

the direct

a heart attack,

threatening arrhythmias.

Optimum supplementation with vitamins and other essential nutrients is the basic therapeutic measure for prevention and treatment of arrhythmias.

encourage my colleagues

I

in

clinical

medicine

to help

information as soon as possible for the benefit of your

and

A

spread

own

this

patients

millions of others.

special note

is in

order for patients with irregular heartbeat

among my

readers:



You should

start

immediately to supplement your diet with vitamins and

other essential nutrients.



While following the recommendations of

this

book, do not discontinue

your regular medication without consulting your doctor.



Share your health improvements with your doctor. Together you can

make

the best decisions to reduce your regular medication.

151

HOW YOU CAN

LONGER AND STAY HEALTHY LIVE

"Your Body

Is

as Old

as

Your Cardiovascular System."

Aging

is

directly

a slow form of cardiovascular disease. The speed

dependent on the health

of

If

your body

is

which your body ages

your cardiovascular system.

body are connected by a 60,000 miles long blood vessel



at

All

organs

of

is

your

pipeline.

unprotected, the aging process leads to a gradual thickening of your

blood vessel walls. This wall thickening eventually leads to malnutrition of millions of



body

cells in

every organ and every other part of your body.

Vitamins and other essential nutrients protect your blood vessels. Optimizing the health of your blood vessel system

from early aging, to

live

longer,

Further Information: Biosca

DG

and

is

the most effective

to enjoy

a healthy

1982; Pauling L 1986

way

life.

to

prevent your body

152

OTHER RECOMMENDATIONS TO MAINTAIN OPTIMUM CARDIOVASCULAR HEALTH

What Else You Can Do

to Protect

Your

Cardiovascular System: Exercise Regularly



Eat a Prudent Diet



-

In

Rich

Low

in Fruits,

in

Fat

Vegetables, and Fiber

and Sugar



Stop Smoking



Find Time to Relax

addition to nutritional supplements, the

lifestyle in

exercise, a

diet rich in fruits,

vegetables, and fiber and low

means you should stop smoking in order smoke to damage your blood vessels and Those among my readers who are cardiovascular Dr.

Dean

body also greatly benefits from a healthy

general. Important for the health of the cardiovascular system are

lifestyle will find

to

in

sugar and

fats.

regular

By

all

prevent toxic substances from cigarette

other parts of your cardiovascular system.

interested

additional advice

in in

learning

books

Ornish, Dr. Julian Whitaker and other colleagues.

more about a healthy

written

on

this subject

by

153

NOTES

154

SECTION

G

ERADICATING HEART DISEASE



Why

Cardiovascular Diseases Are so Closely

Connected



How

to

Vitamin Deficiencies

an Accident

in

the Molecules of Inheritance

Our Ancestors, Thousands Is



of

in

Generations Ago,

the Basis for Cardiovascular Diseases Today

Why

Today's Cardiovascular Diseases Originated

During the Ice Ages



Why

Future Generations of Mankind Will Rarely Die

From Cardiovascular Diseases •

What the White House Says About the of Eradicating



Possibility

Heart Disease

What You Can Do

to Help Eradicate Heart Disease

155

HOW OUR ANCESTORS LOST THE

TO

ABILITY

MANUFACTURE VITAMIN C Sugar

Enzyme

Molecule

OK

Vitamin

C

Enzyme

ANIMAL

HUMAN

LIVER

LIVER

Daily Vitamin of 1

Throughout

C

Production

this

-

health.

animals manufacturing a sufficient amount of

humans, unable

the millions from cardiovascular diseases.

Vitamin

consequences

Most

living

for

our

own

is

so important that bodies generally

own

vitamin C, die by

manufacture

to

C

this vitamin in their

How

did the

their

human

manufacture vitamin C? What were the consequences the

for

race lose the

C

own bodies. They way they manufacture to 20 grams) per day compared to the human vitamin C requires enzymes. Enzymes are

species produce a sufficient amount of vitamin into vitamin C.

body weight. Converting sugar

into

biological catalysts or converters,

symbolized

the figure

in

in their

In this

above as a

these cars (enzymes) are necessary for converting a sugar molecule If

one

of

ability to

our ancestors? What are

health today?

do so by converting sugar molecules between 1,000 mg and 20,000 mg (1

molecule.

-

that vitamins, particularly vitamin C, play a critical

and restoring cardiovascular

don't suffer heart attacks;

Production

(Zero)

-

book we have seen

role in maintaining

C

Our Human Bodies

in

mg

20,000

C

Vitamin

Produced

Daily Vitamin

Most Animals

,000

No

Defective

Produced

these cars breaks down,

this

pathway

is

cut

car. into

Several of a vitamin

C

and no vitamin C

molecules can be produced.

Thousands molecules

of

generations ago our ancestors

into vitamin

C

in

their livers.

This

lost the

was

ability

to

convert sugar

the result of an "accident"

in

the

genes (molecules of inheritance) illustrated in the figure above as a car breakdown. As a result of this genetic accident all descendants, including all human beings living today, are dependent on sufficient dietary intake of vitamin C. For many thousands of

generations this genetic mishap did not bother our ancestors greatly since they

found plenty of vitamins

in their diet

vitamin rich plant nutrition.

guaranteed the

A

stability of their

changed dramatically

with the

consisting mainly of

sufficient vitamin supply

bodies, and

dawn

in

of the Ice

Further Information: Burns JJ 1957; Nishikimi

fruits, in

vegetables, and other

the diet of our ancestors

particular, of their

Ages.

M

1991

blood vessels.

This

156

DURING THE ICE AGES SCURVY BECAME THE GREATEST THREAT TO THE SURVIVAL OF OUR ANCESTORS During the Ice Ages Millions of Our Ancestors Died From Scurvy

Generations Ago

4.000

2,000

Today

Several thousands of generations ago the global temperature dropped and the Ice

Ages Each

last Ice

peak

We know today that several Ice Ages have occurred on our planet. Age lasted over several thousands of generations for our ancestors. The Age occurred between 4,000 and 500 human generations ago. During the this Ice Age half of Europe and North America were covered with ice. Yet we

started. Ice

of

know from skeletons found

were living under these harsh climatic bones show the greatest problem for our ancestors: for food, and their vitamin intake was close to zero.

that our ancestors

conditions. Their malnourished

they were fighting a daily battle

became a constant C was the greatest problem. While other living beings produced their own vitamin C in their bodies, our ancestors had lost this ability. In addition, they now found little vitamin C a deadly in their diet. The inevitable consequence for many of them was scurvy, During the Ice Ages malnutrition and lack of vitamins

threat to the survival of our ancestors.

Among

all

in their

disease. During the thousands of generations that the Ice

ancestors died from lack of dietary vitamin

human

generations, the vitamin

to the survival of the

human

Further Information: Rath

M

C

C and

Ages

1992a and 1992d.

lasted, millions of our

from scurvy. Thus

deficiency disease, scurvy,

race.

diet

deficiencies a lack of vitamin

was

for

thousands

of

the greatest threat

157

SCORBUTIC BLOOD LOSS WAS THE MAIN CAUSE OF DEATH DURING THE ICE AGES During the Ice Ages Leaky Blood Vessels and

Blood Loss

Killed Millions of

Our Ancestors

High

Vitamin

C

Intake in

Diet

High Vitamin

C

Intake

-> Healthy Blood

Diet

in

Vessels

Low Low

->

Warm

Scurvy

is

Period

Ice

a deadly disease. Death

The

killed millions of

total lack of

vitamin

out.

We

know

C

in

become

organs

first

a lack

of vitamin

C

Diet

massive blood loss

to

minimum production

fail

of collagen, the

are the blood vessel walls. During

destabilized: blood leaves the blood stream

that bleeding of the

gums was an

The

massive bleeding inside and outside to

in

Age

caused by

primarily

the diet leads to a

ship voyages of earlier centuries.

due

Intake

our ancestors.

body's cement molecules. The scurvy, these walls

is

C

During the Ice Ages scurvy and leaky blood

through a leaky blood vessel wall. vessels

or Zero Vitamin

Scurvy -> Leaky Blood Vessels

sailors

and leaks

early sign of scurvy during the long

on these journeys eventually died from

their bodies.

They died

after only

a few months

in their diet.

C in the diet of our ancestors was scarce not only for a many thousands of years. Over thousands of generations the scurvy epidemic raged among our ancestors. Millions of our ancestors died from massive blood loss through leaky blood vessels. the human race were to survive, the bodies of our ancestors had to come up with ways to protect the blood vessels from becoming leaky. We know today that they did come up with solutions. During the Ice Ages vitamin

few months

-

but for

If

Further Information: Rath

M

1992a and 1992d.

158

REPAIR MOLECULES BECAME MATTERS OF LIFE AND DEATH DURING THE ICE AGES C

Protection of the blood vessel wall during vitamin

death

for

our ancestors

were they able

The keys

living

during the Ice Ages.

blood vessel protection were repair molecules. These repair

molecules entered the blood vessel wall during vitamin

and

repairing

was a matter of life and come up with? How

did they

blood vessels?

to protect their

for the

deficiency

What

stabilizing

it.

C

transporting particles, other adhesive molecules able to

mend

vessels, clotting factors which could coagulate the blood before

many

with the aim of

deficiency

Favorite repair molecules were lipoprotein(a), other fat

the leaky blood

it

leaked out. and

Ages these repair factors had a great they became life saving. Only those among our

other repair factors. During the Ice

advantage,

fact

in

so great that

who had

ancestors

inherited these repair molecules could survive the threat of

scurvy.

These

repair factors

and



to

rise



to

stabilize

to

and

The advantage Let's

figure.

had

become

to

meet two requirements: whenever the body

effective

of

C

living

is

shown

any repair molecules.

unprotected vessels All

from scurvy.

become

in

the following

during the height of the last Ice Age,

about 50,000 years ago. Our Ice Age family has four children, three inherited

drops

deficiency

these repair molecules during the Ice Ages

imagine an Ice Age family

C

level of vitamin

repair the blood vessel during vitamin

of

whom

have not

Without repair molecules their blood vessels are

Immediately after these babies are born

leaky since lack of vitamin

C

is

their

blood

a lasting threat during the Ice Ages.

three children die as babies or during childhood from scurvy and from massive

blood loss through their leaky blood vessels.

Luckily,

one

child in our family

has inherited the lipoprotein(a) repair molecule

another type of repair molecules or repair mechanism). With low vitamin lipoprotein(a) molecule enters the blood vessel wall

child

is

fortunate

enough

importantly this child

to

and prevents

it

C

(or

intake the

from leaking. This

become an adult. Most own and can pass on the

survive childhood and to

now can have

children on

information for this repair molecule to

its

its

children, grandchildren,

and

further

generations via the genes (molecules of inheritance).

During the Ice Ages only those

among

our ancestors

who

carried these repair

pass these repair genes on to the next generation. This repair information was then passed on in their genes from one molecules

in

their

genes stayed

alive to

generation to the next, from the Ice Ages to our bodies today.

159

Thickening of the Blood Vessel Walls

Was

a Live Saving Mechanism

During the Ice Ages

Ice

Age Family

Parents

Children

Inherited Repair

Molecules

for

Blood

Vessel Repair [Lipoprotein(a)

Many

Problems in Blood Vessels Ice

and

Others]

of

Age Children

Child Lives

Consequences for Ice Age Children

Death During Childhood

Death During Childhood

From Blood Loss

From Blood Loss

Becomes Adult

Has Children

Death During Childhood

From Blood Loss

160

TODAY'S CARDIOVASCULAR DISEASES ORIGINATED DURING THE ICE AGES Ice

Today

Ages

Vitamin Deficiency

Vitamin Deficiency

and Leaky Blood Vessels

in

Our

Diet

Today

+

* Inherited Disorders Leading to Thickening of Blood Vessel Walls

Were Passed on

for

Thousands

of

Generations

Until

Today

*

I

Average Life Expectancy of Our Ancestors Was Below 30 Years

Average Life Expectancy More Than Doubled

They Died Young From Different Causes

Cardiovascular Diseases

I Became Mass Epidemic

Inherited disorders leading to the thickening of the blood vessel wall or protecting

in

another way against death from scurvy were greatly favored during the Ice Ages. Moreover, the genetic information of

generations

until

for

these diseases was passed on over thousands

today. Thus, our bodies today contain genetic information greatly

influenced and shaped during the extreme nutritional conditions of the Ice Ages.

On

new understanding we can suddenly explain Why most inherited disorders known today lead to cardiovascular diseases Why most people living today carry some form of inherited disorder

the basis of this • •

predisposing them for cardiovascular diseases •

Why

today every second death

is

caused by heart

attacks, strokes,

or other forms of cardiovascular disease

We

can now also explain the close connection

deficiencies.

Throughout

this

of cardiovascular

disease

book you may have wondered about

effectiveness of vitamins, particularly of vitamin C,

in

to vitamin

the broad

the prevention of heart

diseases. The Ice Age-vitamin deficiency-cardiovascular disease connection

is

the

reason why •

all

disease mechanisms leading

to

heart attacks and

many

other forms of

cardiovascular diseases can be prevented by supplementation of vitamin

C and

other essential nutrients •

all

blood

vitamin

risk factors

C and

known today

in

other essential nutrients.

clinical

cardiology can be neutralized by

161

DEFUSING INHERITED TIME BOMBS IN OUR BODIES

The

Ice

Ages

greatly influenced the genetic information

grandparents, and earlier generations

genetic information

in

in

our blood

we

received from our parents,

As a

lines.

result,

our bodies predisposing us to develop

most

of

us carry

some form

of

we grow older. Since we don't know when this disease will strike we carry a genetic time bomb in our body. These time bombs can be high lipoprotein(a) levels, high triglyceride levels, diabetes, and many other inherited

cardiovascular disease as

disorders which predispose us to develop cardiovascular diseases. picture of an inherited biological time

importance

When

this

of this

time

bomb

I

will

use the

ticking in our bodies to illustrate the

discovery for your personal health.

bomb explodes

leads to a heart attack

it

another person, and to diabetic cardiovascular disease

one person,

in

in

to strokes in

yet another person. Since

we are unable to change our molecules of inheritance we cannot get rid of the time bomb itself. But we can do something else we can defuse this bomb and prevent its activation. How do we do this? -

The discovery

of the Ice

Inherited time

bombs

way

-

Age-cardiovascular disease connection reveals the answer:

leading to cardiovascular disease are

our blood vessel walls today

is

triggered

in

optimum vitamin supplementation

bombs

in

in

same way as

the

bodies of our ancestors during the Ice Ages:

time

all

activated

in

the

same

by a low dietary intake of vitamins, particularly of vitamin C. The thickening of

our diet

our bodies thereby preventing

it

was

by vitamin deficiency. will its

triggered

in

the

Consequently,

defuse and deactivate the inherited explosion

in

form of heart attacks or

strokes.

The

following figure

summarizes

health of millions of people.

this

important

mechanism which

directly affects the

162

Figure A:



Most

of

us carry inherited time

cardiovascular disease later •

bomb explodes

the

If

diseases •

bombs

in life

not protect ourselves.

strikes.

The common

Optimum

our bodies predisposing us to

in

we do

a heart attack, stroke, or any other form of cardiovascular

trigger

mechanism

for the activation of the inherited

and a low vitamin body

insufficient dietary vitamin intake •

if

vitamin supplementation and an

keeps the inherited time bomb

optimum

bomb

an

is

pool.

level of the vitamin

body pool

and keeps the person healthy.

inactive

Figure B:



Everybody carries a in

• •

different type

bomb

it

The bigger to



different size of inherited time

The more aggressive the inherited disorders, the bigger the time bomb. The bigger the time bomb, the earlier normally explodes leading to heart attacks and strokes early



and

the body.

the

the

bomb, the higher the required

thirties, forties, or fifties).

level of the vitamin

body pool

defuse and deactivate the inherited time bomb.

Since most it

in life (in

is

of

us don't know what size of inherited time

bomb we

carry

safe to take vitamin supplements on a regular basis.

Figure B also gives you an example for this discovery:

Patient

1

carries the genetic time

diabetic cardiovascular diseases

drawn

in this

Patient

2

figure

is

sufficient to

carries the genetic time

bomb

'diabetes' which

later in this

patients

-if

life.

unprotected-

keep the time bomb defused

bomb

will

lead to

The vitamin body pool present time.

at the

'high lipoprotein(a) level'

which

will

lead to a

The vitamin body pool drawn in this figure is not sufficient to time bomb inactive and therefore atherosclerotic deposits are already

heart attack or stroke.

keep

this

building

up

in

the arteries of this patient.

Patient 3 has both inherited disorders 'diabetes' and "high lipoprotein(a)' and therefore

bomb in the body. The vitamin body pool drawn in this enough to keep this huge time bomb defused; in fact the fuse has already burnt down and the bomb is just about to explode in form of a heart attack or carries a

figure

is

huge

by

inherited time

far not

stroke.

Thus, the higher the inherited

outbreak

of

risk,

cardiovascular diseases.

the

more vitamins are needed

to

prevent the

163

Bombs

Figure A: Vitamin Supplementation Defuses Time Inherited Disorders

of

Our Bodies

*-

Vitamin Body Pool

Time Bomb

in

of

Inherited Disorder

\

/ ^Ja Low

r Optimum

Level of

Vitamin Body Pooi

Activates Inherited

Level of

Vitamin Body Pool

Time Bomb

Keeps Time Bomb Defused

and Deposits Develop

r Bomb

Explodes

in

Form

of

You Stay Healthy

Heart Attack or Stroke

Figure B:

The More Aggressive the

The More Vitamins Are Needed

to

Inherited Disorder

Defuse the

-

Bomb

r Patient

3

1

Diabetes

High Level

of

Lipoprotein(a)

Diabetes High Level

of

Lipoprotein(a)

I

164

THESE DISCOVERIES MAY LEAD TO THE ERADICATION OF MANY OTHER DISEASES The

Ice Age-vitamin deficiency-cardiovascular

"Inherited diseases

disease connection says:

leading to thickening of blood vessel walls or

protecting the vessel wall

another way during vitamin deficiency

in

Ages

were greatly favored during These diseases can be prevented and treated by optimum originated during the Ice

or

that time.

intake of

vitamins, particularly vitamin C."

On

the basis of this discovery the following diseases

eradicated as well since they involve of the blood vessel walls

-

many

in

different

may now be

ways

-

thickening

:

Diabetes

Homocystinuria

Morbus Cushing Addison's Disease Alzheimer's Disease

Amyloidosis Neurofibromatosis Cystic Fibrosis Multiple Sclerosis

Muscular Dystrophy Parkinson's Disease

Rheumatoid

Arthritis

Lupus Erythematodes Scleroderma Connective Tissue Disorders Metabolic Storage Diseases Inherited Disorders Leading to High Blood Pressure

Inherited Disorders Leading to Increased Blood Clotting

Further

Information:

Genetic Disorders Associated With Cardiovascular

Diseases (Reviews): Perloff JK 1992; Pyeritz Williams -

GH

1992. Vitamin Deficiency

And

Addison's Disease: Wilkinson JF 1936.

1975.

-

-

RE

1992; Stollermann

Homocystinuria: McCully

Diabetes: Pfleger

R 1937;

GH

1992;

KS 1971. Mann GV

165

Diseases involving the thickening

The

of arteries

can be divided

group includes those diseases leading

first

to

two main groups.

into

open cardiovascular problems

such as heart attacks and strokes, which have been the main focus

These pages are devoted

second group

to the

leads to a thickening or hardening of

of diseases. This

many body

book.

of this

group

tissues but at the

of

diseases

same

time also

leads to a thickening of the patient's blood vessel walls. This fact suggests that these disorders also originated during to the Ice Ages,

when

they protected our ancestors

from scorbutic blood loss and from death. These diseases were less

no protection

better than

We now

at

efficient

than

however, they were

typical cardiovascular disorders in protecting the blood vessels; all.

understand that not only lipoprotein(a) and other

fat

globules stabilized the

blood vessel wall during vitamin deficiency and pre-scurvy, but also complex sugar

molecules, amyloids and other large proteins, connective tissue molecules, even

immune complexes deposited few molecules

mechanism

protective

in

the blood vessel wall were of advantage. There were

the bodies of our ancestors which nature did not

in

try

out as a

death from scurvy and from scorbutic

to avoid the alternative:

blood loss.

These discoveries are not only thousands

The

Ice

of patients suffering

Age

-

of scientific value.

from any

vitamin deficiency

of the

above no other

is

even more

of great

listed

importance

for

on the previous page.

vascular wall connection says that these diseases

-

can be prevented and treated by optimum intake nutrients. This fact

They are

diseases

of vitamins

significant since for

effective treatment

is

With the authority of the scientist

most

and other essential dreaded diseases

of the

available today.

who made these

discoveries

I

am

urging

my

readers:



Patients with any of the diseases listed diet with vitamin



Doctors

about

who this

C and

other essential nutrients discussed

treat patients with disorders listed

in this

their

book.

above should inform

their patients

therapeutic possibility since for most of these diseases no other

effective treatment



above should immediately supplement

Researchers active include vitamin

is

in

C and

available.

developing treatments

for

other essential nutrients

these diseases should immediately in

their

research

efforts.

166

YOUR CARDIOVASCULAR HEALTH DEPENDS ON AN OPTIMUM VITAMIN POOL IN YOUR BODY

How

are the different risk factors for cardiovascular disease connected?

smoking more important than an figure summarizes the answer.

inherited disorder for diabetes?

Three factors determine whether and when you



Internal Risk Factors:

which



we discussed

The

External Risk Factors: in

vitamins,

size of the time

in this

The

particularly

suffer a heart attack

bomb

The

and

Is

following

stroke:

of inherited disorders in

your body

section of the book.

rate at

in

which external

vitamin C, a

risk factors drain

your body pool

mechanism we discussed

in

an

earlier

section of this book. Smoking, stress, being overweight and other forms of an

unhealthy

lifestyle

deplete your body of vitamins. The more of these

risk factors

you accumulate, the faster your vitamins body pool drops.



Your Vitamin Body Pool: Ultimately, your health

is

determined by the

level of

your

vitamin body pool. By supplementing your diet with vitamins and with other essential nutrients you can neutralize an increased cardiovascular risk

by any internal or external

The adjacent

figure

caused

risk factors.

shows the two faucets by which you can

regulate your personal

vitamin body pool.



Faucet number one: Optimum vitamin of

nutrients

is

the safest

way

to

is

the most important regulation

achieve an optimum level of your vitamin body pool

and thereby optimum cardiovascular •

intake. This

your vitamin body pool. An optimum intake of vitamins and other essential

health.

Faucet number two: Decreasing external risk factors. Since we cannot influence our inherited risk factors we should always try to minimize our external risk factors.

Above

all,

stop smoking.

167

Regular Dietary Vitamin Supplementation the

Key

to

is

an Optimum Vitamin Body Pool

Dietary Intake of Vitamins

Most Important: Vitamin C

6 6

^

High

You Stay Healthy

t Vitamin

Cardiovascular Disease Develops

Acute Vitamin Deficiency

(e.g.

Scurvy)

External Risk Factors

of

Smoking



Stress



Birth Control



Others

Pill

Inherited Disorders in

i Low



Time Bomb

Body Pool

Every Person

AFf©

168

THE ERADICATION OF HEART DISEASE IS IN

SIGHT

The Faster This Information About Health The Sooner Heart Diseases

Benefits of Vitamins Spreads

Will

Be Eradicated

Worldwide Deaths From

\

Heart Diseases

More Than 500 Million People Died From Preventable

-

Heart Diseases

-

/

-

in

the

Past 50 Years

/

Level of Information

About Value Vitamins

in

of

Heart i

Disease Prevention

i

i

i

1980

1940

How

fast cardiovascular

about the value

In

2020

T0DAY

diseases can be eradicated depends on how fast information

of vitamins in the prevention of

these diseases

is

spread.

1941 the Canadian Cardiologist Dr. Paterson reported that four out of

C

diseases patients had low vitamin than 50 years ago the

saved

if

this report

first

blood levels as as leading

alarm bells were rang.

How many

would have entered the textbooks

World Health Organization more than 12

million

of

lives

medicine? According

-

more than

in all

billion

wars

together. Thus, ignoring these early studies on the value of vitamins

prevention had a terrible death

toll.

Most

regrettably, the death of

most

many

countries of the world there

of a father,

drama

is

a

sister,

of

of in

people died

mankind taken heart diseases

these people could have been prevented.

we have

In

hardly any family which has not suffered the loss

an uncle who died from a heart attack or stroke. The scope

worldwide and

diseases?

is

to the

people die every year from heart

attacks and strokes. Thus, during the past half century about half a

prematurely from cardiovascular diseases

five heart

Thus more could have been

risk factor.

to ask:

Why

are people

still

of this

dying from preventable

169

WHY PEOPLE CONTINUE TO

DIE

FROM

PREVENTABLE DISEASES I

am

frequently asked

"Why

did

nobody

This page

will

tell

us this important information before?"

give you an answer:

Vitamins are not patentable.

Vitamin sales give small

Little

interest exists

profits.

from pharmaceutical companies.

Vitamin research receives scarce financial support.

Little

Few

money

is

made

available for clinical studies with vitamins.

reports about value of vitamins are published

Health benefits of vitamins are hardly ever mentioned

Few

medical journals

in

medical textbooks.

universities teach nutritional medicine.

Few medical

Few

in

students learn about nutritional medicine.

doctors

Millions of

know and

practice nutritional medicine.

people continue

to die

from heart disease

and from other preventable diseases.

170

HOW WE CAN STOP UNNECESSARY DEATH TOLL AND HELP CREATE A BETTER AND HEALTHIER TOMORROW THIS

The key to turning this dreadful development around is information. The message of this book should reach every country and every family as soon as possible. You can help. Talk to your family, to your friends, and your colleagues about this book. You can also send a copy of this book to your local

newspaper, radio or TV station

Other steps which should be

for review.

taken immediately include:

and educational

Doctors, health care professionals, students, in

research and nutritional medicine

nutritional

No

institutions

the health care field share an ethical responsibility to introduce

future doctor should

knowledge

Scientists

and more

in nutritional

into their

teaching programs.

leave medical school without a profound

medicine.

and researchers have an urgent responsibility. More research clinical studies are needed to document the health values of

essential nutrients.

New

based on

research and

scientific

nutritional

compositions should be developed

clinical tests.

public institutions should develop a focus

in

Universities this

and other

important area of

medicine.

Scientific

and medical journals as

responsibility

in

important area of medicine. They clinical

On

studies

in

well as the

media

in

general share a

disseminating the scientific progress

nutritional

the next page you

will find

made

in

should regularly report the research

medicine.

some

personal recommendations for you.

this

and

171

MY PERSONAL RECOMMENDATIONS FOR YOU



Use

book as your personal advisor to improve your cardiovascular health and to add valuable years to your life. this

Follow the recommendations of this book and optimize your cardiovascular health with nutritional supplements. Enjoy leading a healthy

life

style.

you have a heart condition inform your doctor about the health improvements you achieve by following the recommendations of this

If

book.

Do

not stop taking your regular medication without consulting your

doctor.

Talk to your family, friends, and colleagues about following the

recommendations

Enjoy taking control of your

own

cardiovascular ailments and to

how you

feel while

of this book.

all

health

and look forward

those years you

will

to

a

life

without

add.

The health improvements grateful patients shared with you throughout this book may help you personally. In return, encourage you to also share the health improvements you may experience while following the recommendations of this book. While staying anonymous, your health message can be of great importance to thousands of other people. You can I

send your

letter directly to

me

at the

address you

find at the

end

of this

book.

172

"CALL FOR EXCELLENCE

HEALTH CARE"

IN

AN INVITATION TO MY COLLEAGUES IN MEDICINE AND IN OTHER HEALTH CARE PROFESSIONS This book provides the scientific rationale as well as great

advancement

advancement does invite

I

my

clinical

evidence

medicine. Before long, nutritional medicine

health care areas and millions of people

all



in

come by

not

colleagues

in

itself

-

medicine and

it

in

will

benefit from

will

it.

for

a

reach

But this

needs your support. other health care professions to

further improve the health of your patients by

making use of the recommendations of this book. invite you to document the health improvements of your patients and, possible, conduct clinical tests and studies to further document the health benefits of essential nutritional

I

if

nutrients.



invite

I

the health maintenance organizations and health insurance

companies

breakthrough. The documented in this book are just the tip of the iceberg. Imagine the efficiency improvement for our health care system these recommendations are followed by your members or policy holders. to

take advantage of this medical

testimonials from patients

if



I

invite the

promote

Take

medical students and

this fascinating

this

book

medicine part

I

of the

founded Health

education in this

in

to

area

future health professionals to help

medicine during your

your medical school and help to

make

lifetime.

nutritional

ongoing education.

Now

to

promote research,

nutritional

medicine.

we

help you

area and

all

of nutritional

will

We in

clinical studies

as well as

are open for any form of collaboration

any way we can.

If

you are interested

-

don't hesitate to contact us.

Based on the scientific discoveries reported in this book a series of political measures are also immediately needed. On the following pages would like to share with you my open correspondence with the White House in I

Washington.

173

SAVE LIVES AND REDUCE THE HIGH COSTS OF HEART DISEASE Open

Letter to President Bill Clinton, Vice-President Al Gore, and Health Care Task Force Chair Hillary Clinton

Dear President Clinton, Dear Vice-President Gore, Dear Hillary Clinton: letter is to inform you about recent scientific discoveries that open the way to significantly reduce heart attack and stroke for millions of people At the same time these discoveries will lead to a

This the

risk for

necessary change and a

significant

improvement

of

America s health care and

to

a great reduction

of health care

costs.

The •



-

facts on heart disease are alarming Ever year more than 1 million Americans die from heart disease - two Americans every minute Every year more than 100 billion US dollars in health care costs are spent for heart disease alone 200,000 US dollars every minute

Over the years

knowledge has accumulated about the value

of vitamins and other essential former capacity as Director of Cardiovascular Research at the Linus Pauling Institute of Science and Medicine in Palo Alto had the opportunity to review much of this evidence In addition, have contributed to this knowledge a series of discoveries which provide us with a new understanding of heart disease and with effective treatments for it. scientific

nutrients in the prevention of heart disease

In

my

I

I

• Heart disease is a vitamin deficiency disease Heart attacks and strokes are essentially unknown in all animals producing sufficient vitamin C in their bodies Among humans, unable to produce their own vitamin C and frequently having a low dietary intake of vitamins, this disease became a leading cause of death Virtually every form of heart disease known today can be induced by vitamin C deficiency

• Vitamin C stabilizes the wall of the blood vessels and is needed for the production of collagen the reinforcement for the blood vessel wall and other parts of the human body A reinforced blood vessel wall does not allow atherosclerotic deposits to develop Thus heart attacks and strokes can largely be prevented by an

optimum intake

of vitamin

C

The most important

risk factor for heart disease known today is lipoprotem-a which directly or indirectly heart attacks and strokes Neither diet nor any of the presently available cholesterollowering prescription drugs is known to affect this newly identified risk factor In contrast vitamin C and vitamin •

causes over

B3 as

50%

of

all

as the natural amino acids lysine and proline can be therapeutically effective Moreover these supplements have the potential to reduce existing atherosclerotic deposits and thereby to reverse heart disease in a non-surgical way

well

nutritional

existing

A century ago scientific discoveries were made which lead to the control of infectious diseases The knowledge available today on the important role of vitamins and other essential nutrients in the fight against heart disease will lead to the control of this disease during the next decades As the physician and feel is incumbent upon scientist who made the discoveries which lead to the recent scientific break-through me to inform you about this development in order to enable your administration to make appropriate decisions towards a significant improvement of human health These discoveries are summarized in my recent paper Reducing the Risk for Cardiovascular Disease with Nutritional Supplements and m my forthcoming book scientific

I

entitled

The

Abolition of Heart

Disease

it

1

174

It is no coincidence that the US the nation with the highest per capita vitamin consumption, has already achieved the greatest decrease in the rate for heart disease among all industrialized nations In a recent epidemiological study trom the University of California at Los Angeles involving more than 1 1 000 Americans a modest dietary Vitamin C supplementation cut the heart attack rate in half and increased life expectancy for up to six years No other drug or compound has ever been shown to have a similar effect

Half a century risk factor for

ago

clinical

studies had

documented

C

that low vitamin

heart disease Unfortunately these reports were ignored, and

in

levels

in

the blood were a leading

the 50 years since

more than

half

a billion people died unnecessarily from heart attacks and strokes The death toll from these preventable diseases is greater than from all wars of mankind combined There is no rational explanation why this important information has been ignored There may. however, be an economic reason Vitamins and other essential nutrients are not patentable and have had few advocates promoting this knowledge essential for millions of patients What is particularly alarming is that today the Food and Drug Administration intends to make vitamins and essentia) nutrients prescriptive drugs and thereby to limit their free and affordable access -

-

any longer. The optimum use of nutritional supplements in the prevention and therapy for heart disease and many other diseases A change of the Nation s health care towards an effective therapy at low cost will also have immediate implications for the economy Effective safe and affordable health care on the basis of nutritional supplements is a realistic and logical way believe the only way to implement your most important campaign promises

There

is

no

scientific, ethical, or

economic reason

to neglect this important information

health of millions of Americans can and must immediately be improved by

-



Provide health care to



Reduce



Decrease the budget



all

Amencans

at affordable

costs

health care spending deficit

Increase the competitiveness of Americas businesses by

decreasing

their health

care expense burden

In the name of millions of present and future patients urge you and your administration to immediately a scientific and clinical program through the National Institutes of Health and by other measures you consider appropriate to irreversibly establish the benefits of nutritional supplements for human health Your support for this new era of medicine will require courageous stands against some pharmaceutical companies but the immediate benefits for the health of the people, for thousands of small and large businesses, and for the overall economy of this country will reward this courage manifold I

initiate

an international medical and from heart disease 50 years ago the Manhattan Project, a joint effort by the world s leading scientists initiated by President Roosevelt ended the Second World War by creating the atomic bomb Now is the time to initiate a scientific effort to win another war - the war against heart attacks strokes and other diseases The goal is clearly defined a significant reduction of heart disease as a

You and your administration now have a

scientific effort to greatly

cause

for

human

reduce death and

mortality in this generation

historic opportunity to lead

disability

and

in

future generations of

mankind

Towards this goal have recently founded a company committed to the promotion of nutntional medicine by focussing on research and clinical studies as well as educational services We will pursue the goals outlined above through collaboration with physicians scientists, health organizations and we are open to any form of collaboration with your administration I

Very

truly yours.

Matthias Rath.

MD

For more information please contact Health Now. 387 Ivy Street San Francisco. California 94102

175

A FIRST RESPONSE FROM THE WHITE HOUSE

TH

E

WH ITE HOUSE

Dear Friend:

Thank you

for writing and sharing your views on health care reform. President Clinton is committed to reforming our nation's health care system controlling runaway costs and providing security to every



American

family.

won't be easy and it won't happen overnight, but with your help, we bring costs under control while maintaining quality medical care and preserving the choice so important to us all. It

will

Thank you again

for

your views and

for

your support.

!^ll^i^

C^

/ Health

Now 387

Ivy Street

San Francisco CA 94102

177

ADVOCACY FOR A NEW ERA IN MEDICINE A PERSONAL CHRONOLOGY 1940

-

1980

and

Early research

clinical

studies

medicine are largely

nutritional

in

-

ignored. Proponents of vitamins are frequently considered "quacks."

1980's More research and

clinical

studies are published about the health value of

The value

vitamins and nutritional supplements.

1987 Discovery

of the

vitamin C. For the levels

C and E

as natural

connection between cardiovascular disease, lipoprotein(a) and

first

time vitamin

order to lower this

in

of vitamins A,

becomes known.

antioxidants

C

is

given to a person with high lipoprotein(a)

risk factor.

1989 September: Together with my colleagues from Hamburg about the

of our findings

human

critical role of lipoprotein(a) in

1990 August: Publication

of the

University, publication

atherosclerosis.

connection between lipoprotein(a), vitamin

C and

cardiovascular disease.

1991

April:

Submission

paper "Solution Vitamin in

C

to the

to the

Proceedings

Puzzle of

Human

of the National

Academy

Cardiovascular Disease:

Its

of

Science

of the

Primary Cause

is

Deficiency Leading to the Deposition of Lipoprotein(a) and Fibrin/Fibrinogen

the Vascular Wall".

1991 June: After having originally accepted publication of

this paper, the editor of the

Proceedings denies publication. 1991 November: Publication of the paper "Solution" Medicine, with

century

a foreword quoted from a

who discovered

in

letter written

that the earth circles the

the Journal of Orthomolecular

by Galileo

Galilei in the 17th

sun and not the sun the earth: "My

have offered of the leading philosophers here to whom my own accord to show my studies, but who, with the lazy obstinacy of a serpent who has eaten his have never consented to look at the planets, or moon, or telescope? Verily, just as serpents close their ears, so do men

dear Kepler, what do you say

I

a thousand times of

fill,

close their eyes to the

also added Proceedings I

to the

of

circumstances pullback

who

was

light of truth."

foreword that

the

National

this decision

was

this

paper had

Academy later

originally

Sciences.

of

revoked by the

not the decision of an individual.

It

editor.

happened

been accepted by the "Under questionable We are aware that this in

the interests of those

are personally or economically dependent on the present

cardiovascular disease.

We

proper judgment on this interesting development.

Orthomolecular Medicine that this decision will not

We

to the

disadvantage

human make the

of

will

are indebted to the Journal of

for the publication of this article without

be

dogma

are confident that the scientific historians

of this journal.

delay and

Above

we know we are

all.

178 convinced that the uncompromised publication millions of patients,

of this article lies in the interest of

and perhaps every human being."

November 1991: Copies

paper were distributed

of the "Solution"

Heart Association meeting publication reached doctors

Anaheim,

in

and

scientists

California. in

many

at the

From there

this

American important

countries.

January 1992: Press conference by the American Heart Association. Then president

Brown

Dr. Virgil

vitamins

essentially

acknowledged the

potential health value of

megadoses

of

the prevention of cardiovascular disease.

in

February 1992: Scientific conference on the health benefits of vitamins sponsored by the

New

York Academy

The author's

Deficiency."

Cardiovascular

Human

is

in

to

title "Beyond Theory Of Human This Diseases As A Cause For

Arlington, Virginia, under the

publication

latest

Disease Leading

Mortality"

The

"A

Abolition of

Unified

distributed to the participants of this conference as well as to

media representatives April

Science

of

at the

conference.

1992:The publication "A Unified Theory Of Human Cardiovascular

Leading

to

The

Abolition of This Diseases

As A Cause For Human

Mortality"

Disease is

sent out

to the press.

April

1992: Time Magazine appears with a

New

research shows they

Aging." This issue of

may help Time becomes

And World Report, Readers May

1992: Dr.

their findings

September 1992: Health Now clinical

is

page "The Real Power Of Vitamins

the best selling issue ever.

his

from

cuts heart disease rates and prolongs

through research,

title

Cancer, Heart Disease, and the ravages

and many others

Digest,

James Enstrom and

Los Angeles publish

fight

Newsweek, US News

follow.

colleagues from the University of California 1 1

life.

,000 Americans that vitamin

This study

founded, a

makes

front

company promoting

C

page news. nutritional

medicine

studies as well as educational services.

The White House about the discovery and can now be eradicated.

Clinton informing

are vitamin deficiencies

May 1993

:

A

first

in

significantly

February 1993: Open Letter To President Clinton, Vice President Gore, and

Rodham

-

of

Hillary

that heart diseases

response from The White House acknowledging having received

information about the historic opportunity to eradicate cardiovascular diseases.

179

SOME DISCOVERIES MADE BY THE AUTHOR Major



Scientific Discoveries

Discovery of the Ice Age

-

cardiovascular disease connection. This

discovery explains that today's cardiovascular diseases and

many

related

diseases originated during the Ice Ages.



Discovery that cardiovascular diseases can largely be eradicated

in this

generation and

based

on the

Ice

Age

future generations of mankind.

in -

vitamin deficiency

and on the discovery

that

-

heart

This discovery

is

cardiovascular disease connection

diseases are primarily vitamin

deficiencies.

Discovery of the lipoprotein(a) primarily found

in

humans and

-

vitamin

C

connection. Lipoprotein(a)

is

other living beings unable to synthesize

vitamin C. Vice versa, animals synthesizing vitamin

C have

less or no

lipoprotein(a).

and related compounds can release lipoprotein(a) from atherosclerotic deposits and thereby reverse cardiovascular disease. L-lysine

Discovery of the 'protein code', the communication code molecules

in

of protein

our body. This discovery deciphers the language by which our

body molecules

'talk'

to

each other during health and disease. After the thirty years ago the 'protein code'

discovery of the genetic code more than

has remained the missing recent discovery

link of biological

was published

in

early 1993.

communication. This most

180

Discoveries Which

The

Can Immediately Improve Your Personal

following diseases

may now be

completely eradicated:



Heart attacks



Strokes



Peripheral forms of cardiovascular diseases;



Heart failure



Arrhythmias



Health

Inherited disorders causing high blood pressure



Inherited disorders causing increased blood clotting



Diabetes, Morbus Cushing, Addison's disease, and other hormonal

disorders leading to cardiovascular diseases



Alzheimer's disease, neurofibromatosis, muscular dystrophy, Parkinson's disease, multiple sclerosis and other disorders of the

nervous system which also



Rheumatoid

involve the cardiovascular system

arthritis, polyarteritis,

lupus erythematodes, scleroderma

and other immunological disorders which also involve the cardiovascular system



Inherited disorder causing tissue storage diseases



Inherited disorders of the connective tissue

Some

of

earlier;

these diseases had been connected to nutritional deficiencies

for

most

of

them

book is the first the above diseases

this

opportunity to eradicate any of

report. is

Moreover, the

reported here for the

vitamin deficiency Age cardiovascular disease connection was necessary for this medical

first

time.

The discovery

breakthrough.

of

the

Ice

-

-

181

We

can now eradicate heart disease and several

dozen

of related diseases

nutritional

by optimum use of

supplements.

Doctors, scientists, health care providers, politicians,

all

of

us now share a historic

opportunity to achieve this goal as soon as possible

-

for the benefit of this generation

future generations of mankind.

and

of

182

REFERENCES For editorial reasons only the

Acheson

RM

first

author and the year

is

given

and Williams DRR. (1983) Does consumption

protect against stroke ?

Lancet

1

1 1

:

91

-1

1

in

the text references.

of fruit

and vegetables

93.

Armstrong VW, Cremer

P, Eberle E, et al. (1986) The association between serum Lp(a) concentrations and angiographically assessed coronary atherosclerosis. Dependence on serum LDL levels. Atherosclerosis 62:

249-257. Altschul R, Hotter

cholesterol

in

A and Stephen

JD. (1955) Influence of nicotinic acid on serum

man. Archives

of

Aulinskas TH, Van Westhuyzen

DR

Biochemistry and Biophysics 54: 558-559.

and Coetzee GA. (1983) Atherosclerosis 47:

159-171.

Avogaro

Bon G B and Fusello M. (1983)

P,

lipoproteins

and apolipoproteins

on

Effect of pantethine

lipids,

man. Current Therapeutic Research 33:

in

488-493.

Bates CJ, Mandal AR, Cole TJ. (1977)

HDL

The Lancet II: 611. Beetens J, Coene M-C, Verheyen

Zonnekyn

A,

and vitamin-C

cholesterol

L

& Hermann

AG

status.

(1986)

Prostaglandins. Beisiegel U, Niendorf A, Wolf K, Reblin arterial wall.

Berg

K.

(1963)

T and Rath M. (1990)

European Heart Journal

A new serum

1 1

(Supplement

type system

in

man

-

Lipoprotein(a)

E):

the

in

174-183.

the Lp system.

Acta

Pathologica Scandinavia 59: 369-382.

Biosca DG, Mizushima S,

Sawamura

M, Nara Y, and Yamori Y.

nutritional prevention of cardiovascular

The

diseases on longevity.

effect of

Nutritional

Review 50:407-412.

Blumberg

A,

Hanck A and Sandner G. (1983) Vitamin

nutrition in patients

on

continuous ambulatory peritoneal dialysis (CAPD). Clinical Nephrology 20:

244-250. Bordia AK. (1979) The effects of vitamin

adhesiveness

platelet

in

C on

blood with

patients

lipids, fibrinolytic activity

coronary

artery

and

disease.

Atherosclerosis 35; 181-187. Bordia

A and Verma SD.

(1985) Clinical Cardiology

Boscoboinik D, Szewczyk A, Hensey proliferation

C and

8:

552-554.

Azzi A. (1991) Inhibition of

cell

by alpha -tocopherol. Journal of Biological Chemistry 266: 6188-

6194.

Breslow JL. (1989) Familial disorders Scriver

of high density lipoprotein

CR, Beaudet AL, Sly WS, Valle D

metabolism.

In:

(editors). The Metabolic Basis of

Inherited Disease, p. 1251-1266. McGraw-Hill,

New

York, St. Louis,

San

Francisco Briggs

M

and Briggs M. (1972) Vitamin C requirements and

oral contraceptives.

Nature 238: 277.

Brown

MS

and Goldstein

atherosclerosis.

JL. (1984)

Scientific

How LDL

American 251

:

receptors influence cholesterol and

58-66.

183

Burns

JJ. (1957)

Missing step

man. monkey and guinea

in

pig required for the

biosynthesis of L-ascorbic acid. Nature 180: 553.

Burns

JM, Machlin

JJ, Rivers

Annals

of the

New

Carlson LA, Hamsten

LJ, editors. (1987) Third

York Academy

A and Asplund

levels of lipoprotein Lp(a)

Conference on Vitamin C.

Sciences 498.

of

A. (1989).

Pronounced lowering

of

serum

hyperlipidemic subjects treated with nicotinic

in

Journal of Internal Medicine (England) 226: 271-276.

acid.

Cherchi A, Lai C, Angelino

F,

Trucco G. Caponnetto

Manzoli U, Schiavoni G, Reale A,

Novo

Romeo

F,

S,

Rizzon

Mereto PE, Rosolen G. Sorgente

P,

Strano A.

I,

and Immordino R. (1985) International Journal of Clinical Pharmacology, Therapy and Toxicology: 569-572. Clemetson CAB. (1989) Vitamin C, Volume Mil. CRC Press Inc., Florida. Cushing GL, Gaubatz JW, Nave ML, Burdick BJ, Bocan TMA. Guyton JR. Weilbaecher D, DeBakey ME, Lawrie GM and Morrisett JD. (1989) Quantitation and localization of lipoprotein(a) and B in coronary artery S.

bypass vein

grafts resected at re-operation.

593-603.

Arteriosclerosis 9:

Dahlen GH, Guyton JR, Attar M, Farmer JA, Kautz JA and Gotto AM, lipoproteins with coronary artery Circulation 74:

DeMaio

Jr.

(1986)

plasma lipids, and other disease documented by angiography.

Association of levels of lipoprotein

LP(a),

758-765.

Lembo

SJ, King SB,

Bhagavan HN and

NJ, Roubin GS. Hearn JA.

Sgoutas DS. (1992) Vitamin E supplementation, plasma of restenosis after

and incidence

percutaneous transluminal coronary angioplasty (PTCA).

Journal of the American College of Nutrition

CW.

Dice JF and Daniel

lipids

1 1

:

68-73.

(1973) The hypoglycemic effect of ascorbic acid

in

juvenile-onset diabetic. International Research Communications System:

a 1:

41.

Enstrom JE, Kanim LE and Klein MA. (1992) Vitamin C intake and mortality among a sample of the United States population. Epidemiology 3: 194-202. Ferrari R, Cucchini,

and

Visioli

O. (1984) The metabolical effects of L-camitine

angina pectoris. International Journal Folkers K and

and

Yamamura Y

clinical

Publishers,

aspects

New

(editors).

of

of

Cardiology

5:

in

213-216.

(1976,1979,1981,1984,1986) Biomedical

coenzyme

Q.

Volume

1-5.

Elsevier Science

York.

Watanabe T, Kaji M. (1977) Critique of coenzyme Q10 in biochemical and biomedical research and of ten years of clinical research on

Folkers K,

cardiovascular disease. Journal of Molecular Medicine Folkers K. Vadhanavikit

2:

431-460.

S and Mortensen SA. (1985) Biochemical

rationale

and

myocardial tissue data on the effective therapy of cardiomyopathy with

coenzyme Q10. Proceedings

of the National

Academy

of

Sciences

USA

82:

901-904. Frei B, in

England L and

Ames BN.

(1989) Ascorbate

human blood plasma. Proceedings

USA

is

an outstanding antioxidant

of the National

Academy

of

Sciences

86: 6377-6381.

Gaby SK, Bendich

A. Singh

VN and

and Health. Marcel Dekker

Inc.

Machlin LJ

N.Y.

(editors).

(1991) Vitamin Intake

.

.

184

Gaddi A, Descovich GC, Noseda G, Fragiacomo C, Colombo L, Craveri A, Montanari G, and Sirtori CR. (1984) Controlled evaluation of pantethine, a hypolipidemic compound,

natural

patients with

in

different

forms of

hyperlipoproteinemia. Atherosclerosis 5: 73-83.

Galeone

F,

Scalabrino A, Giuntoli

The

(1983)

J Jr.,

Panigada G, Rossi, and Saba hyperlipidemic patients:

in

Jenner JL, McNamara JR, Ordovas JM, Silberman SR, Wilson

and Schaefer EJ.

P.

a

Current Therapeutic Research 34: 383-390.

clinical investigation.

Genest

F, Birindelli A,

lipid-lowering effect of pantethine

PWF

1991) Prevalence of lipoprotein(a) Lp(a) excess

(

in

coronary artery disease. American Journal of Cardiology 67: 1039-1045.

Gey

KF, Stahelin HB, Puska P and Evans A. (1987) Relationship of plasma level of vitamin

C

from ischemic heart disease. 1 10-123.

to mortality

In:

Rivers JM, Machlin LJ (editors): Third Conference on Vitamin C. the

Gey

New

York Academy

of

JJ, of

Sciences 498.

KF, Puska P, Jordan P and Moser UK.

plasma vitamin E and

Burns

Annals

Inverse correlation between

(1991)

mortality from ischemic heart disease

cross-cultural

in

epidemiology. American Journal of Clinical Nutrition 53: 326, Supplement.

and

Ghidini O, Azzurro M, Vita A, efficacy of L-carnitine Clinical

Ginter E.

in

(1988) Evaluation of the therapeutic

Sartori G.

congestive heart

failure.

International Journal of

Pharmacology, Therapy and Toxicology 26: 217-220. Cholesterol: Vitamin

(1973)

C

controls

its

transformation into bile

acids. Science 179: 702.

Ginter E (1976) Vitamin

C and plasma

lipids.

New England

Journal of Medicine

294: 559-560.

Ginter

E.

Marginal vitamin

(1978)

atherosclerosis.

Lipid

Research

C

deficiency,

Ginter E. (1979) Decline of coronary mortality

Journal of Clinical Nutrition 32: 51

E

Ginter

(1991)

Vitamin

C

lipid

metabolism, and

16: 216-220. in

United States and vitamin C.

1

cholesterol

deficiency

metabolism

and

atherosclerosis. Journal of Orthomolecular Medicine 6: 166-173.

Gore

I,

Fujinami T, and Shirahama T. (1965)

ascorbic acid deficiency

in

Endothelial

guinea pigs. Archives

of

changes produced by

Pathology 80: 371-376.

Grainger DJ, Kirschenlohr HL, Metcalfe JC, Weissberg PL,

RM. (1993) lipoprotein(a).

Proliferation of

human smooth muscle

Wade DP and Lawn cells

promoted by

Science 260: 1655-1658.

Guraker A, Hoeg JM, Kostner G, Papadopoulos NM and Brewer HB Jr. (1985) Levels of lipoprotein Lp(a) decline with neomycin and niacin treatment. Atherosclerosis 57: 293-301 Halliwell

B and Gutteridge JMC

(editors). (1985)

medicine. Oxford University Press, London,

Free radicals

New

in

biology and

York, Toronto.

Hanck A and Weiser H. (1979) The influence of vitamin C on lipid metabolism in man and animals. International Journal for Vitamin and Nutrition Research 19:83-93.

Greene YJ and Stacpoole PW (1986) Inhibition of human coenzyme A reductase activity by mediated by the free radical monodehydroascorbic acid. An effect

Harwood HJ

Jr,

leucocyte 3-hydroxy-3-methylglutaryl

185 ascorbate. Journal of Biological Chemistry 261

Hayashi

endothelium

in

administration.

:

7127-7135.

Scanning electron microscopic observations on the aortic hypovitamin C guinea pigs with or without cholesterol

K. (1980)

Nagoya Medical Journal

Hearn JA, Donohue BC, Ba'albaki

H,

155-168.

25:

Douglas JS, King

Lembo

SBIII,

NJ, Roubin

JS and Sgoutas DS. (1992) Usefulness of serum lipoprotein(a) as a predictor of restenosis after percutaneous transluminal coronary angioplasty. The American Journal of Cardiology 68: 736-739. Heart Facts, American Heart Association, 1987. Hermann WJ JR, Ward K and Faucett J. (1979) The effect of tocopherol on higdensity lipoprotein cholesterol. American Journal of Clinical Pathology 72: 848-852.

Hemila H. (1992) Vitamin

C and plasma

Science and Nutrition 32

(1):

Beck GJ, Skibinski

Hoff HF,

Serum

(1988) artery

cholesterol.

CRC

Press

Jurgens G, O'Neil

CI,

in

Reviews

Kramer

J,

in

Food

and

J

Lytle B.

1238-1244.

Circulation 77:

patients.

Rosenman RH, Bawol RD and Brand

between

In: Critical

Inc., Florida.

Lp(a) level as a predictor of vein graft stenosis after coronary

bypass surgery

Hulley SB,

33-57,

RJ. (1980)

and coronary heart disease.

triglyceride

The association

New England

Journal of

Medicine 302: 1383-1389. Ide T. (1922)

Gefassveranderungen

Zeitschrift fur Kinderheilkunde.

1

bei der Moller-Barlowschen Krankheit.

65-1 77.

(1986) Magnesium and cardiac arrhythmias. Magnesiums: 111-126. LT and French JH. (1984) Magnesium: nature's physiologic calcium blocker. American Heart Journal 108: 188-193. Jacques PF, Hartz SC, McGandy RB, Jacob RA and Russell RM. (1987) Ascorbic acid, HDL, and total plasma cholesterol in the elderly. Journal of the American College of Nutrition 6: 169-174. Kamikawa T, Kobayashi A, Emaciate T, Hayashi H, and Yamazaki N. (1985) Iseri

LT.

Iseri

Effects of pectoris.

coenzyme Q10 on exercise tolerance

American Journal

Kapeghian JC and Verlangieri uptake

in

J.

Life

cells:

possible

pathogenesis

Oklahoma State Medical Association Journal Kojima S, Soga W, Hagiwara H, Shimonaka M. Visible fibrinolysis by endothelial cells:

Bioscience Reports

GM, Avogaro

(1981)

6:

Lipoprotein

Atherosclerosis 38:

Effective

diabetic

dietary intake of calcium.

of

hypertensive subjects.

77: 177-182.

Saito Y, and

Inada Y. (1986)

effect of vitamins

and

sterols.

1029-1033.

Cazzolato G, Marth

P,

Lp(a)

and

the

G and

Qunici GB.

myocardial

infarction.

E, Bittolo-Bon

risk

for

51-61.

K. Lyson K, Muratsu K, Lyson T. and Langsjoen P. and safe therapy with coenzyme Q10 for cardiomyopathy.

Langsjoen PH, Folkers (1988)

of

Sciences 34: 577-584.

Knox EG. (1973): Ischemic heart disease mortality and The Lancet 1: 1465. Koh ET (1984) Effect of Vitamin C on blood parameters

Kostner

chronic stable angina

(1984) The effects of glucose on ascorbic acid

heart endothelial

angiopathies.

in

Cardiology 56: 247-251.

of

186 Klinische Wochenschrift 66:

Langsjoen PH, Folkers

583-590.

Lyson

K,

Muratsu

K.

Lyson

K,

T,

and Langsjoen

P.

(1990) Pronounced increase of survival of patients with cardiomyopathy

when

treated with

coenzyme Q10 and conventional

Journal of Tissue Reactions

Lawn RM. (1992)

Lipoprotein(a)

heart disease.

in

therapy. International

163-168.

XIII (3)

Scientific

American. June:

54-60.

Leaf

A and

The

Hallaq HA. (1992)

role of nutrition in the functioning of the

cardiovascular system. Nutrition Review 50: 402-408.

New concepts in the biology and biochemistry of ascorbic acid New England Journal of Medicine 314: 892-902. Mann GV and Newton P. (1975) The membrane transport of ascorbic acid. Second Conference on Vitamin C. 243-252. Annals of the New York Levine M. (1986)

Academy

of

Sciences.

McBride PE and Davis JE.

Cholesterol and cost-effectiveness

(1992)

and research. Circulation 85: 1939-1941.

implications for practice, policy,

McCarron DA, Morris CD, Henry HJ and Stanton nutrient intake

McCully KS. (1971) Homocysteine metabolism sclerosis.

McKee

Nature 231

PA. Castelli

JL. (1984) Blood pressure

and

the United States. Science 224: 1392-1398.

in

in

scurvy, growth and arterio-

391 -392.

:

WP. McNamara PM and Kannel WB.

history of congestive heart failure:

Journal of Medicine 285:

1

441

-1

the

Framingham

(1971) The natural

study.

New England

445.

McLean JW. Thomlinson JE, Kuang WJ, Eaton DL, Chen EY, Fless GM, Scanu AM and Lawn RM. (1987) c-DNA sequence of human apolipoprotein(a) is homologous

to

plasminogen. Nature 300: 132-137.

Miccoli R. Marchetti P. Sampietro T.

Effects of pantethine on lipids

diabetic

and nondiabetic

Benzi

L.

Tognarelli

M

and apolipoproteins

patients.

and Navalesi

in

R. (1984)

hypercholesterolemic

Current Therapeutic Research 36:

545-

549.

Mortensen SA, Vadhanavikit clinical

with

benefits

breakthrough

in

the

S,

Muratsu K and Folkers

management

Journal of Tissue Research

Murad

S.

Grove

K. (1990)

D. Lindberg KA,

XII (3):

of chronic heart failure.

Academy

of

International

155-162.

Reynolds G, Sivarajah A, and Pinnell

Regulation of collagen synthesis by ascorbic acid. National

Coenzyme Q10:

biochemical correlates suggesting a scientific

Sciences

USA

S.

Proceedings

(1981) of the

78: 2879-2882.

Murai AS, Miiyahara T. Fukimoto N. Matsuda

M & Kamayama M

(1986)

Lp(a)

Lipoprotein as a risk factor for coronary heart disease and cerebral infarction.

Atherosclerosis 59:

199-204.

Majamaa K, Gunzler V. Hanuska-Abel Ascorbate is consumed stoichiometrically

Myllyla R,

catalyzed by prolyl-4-hydroxylase and

HM in

lysyl

and

Kivirikko Kl.

the uncoupled

hydroxylase.

(1984)

reactions

Journal of

Biological Chemistry 259: 5403-5405.

Niendorf A, Rath M. Wolf K. Peters S. Arps H. Beisiegel U and Dietel M. (1990)

Morphological detection and quantification

of lipoprotein(a) deposition in

.

187

atheromatous lesions

human

of

aorta and coronary arteries.

Archives of Pathological Anatomy 41

7:

1

05-1

Virchow's

1 1

(1987) Interaction of ascorbate and alpha-tocopherol.

Niki E.

JM, Machlin

LJ, editors: Third

York Academy

M

Nishikimi

of

In Burns JJ, Rivers Conference on Vitamin C. Annals of the New

Sciences 498: 186-198.

and Yagi

Molecular basis

K. (1991)

gulonolactone oxidase, a key enzyme

for the deficiency in

for

humans

of

ascorbic acid biosynthesis.

Journal of Clinical Nutrition 54: 1203S-1208S.

Opie LH. (1979) Review: Role

of carnitine in fatty acid

metabolism

of

normal and

ischemic myocardium. American Heart Journal 97: 375-388.

Packer M.

(1987)

Prolonging

life in

Supp

next frontier. Circulation 75

patients with congestive heart failure: the IV:

1-3.

Paterson JC (1941): Canadian Medical Association Journal 44: 114-120.

How to Live Longer and Feel Better. WH Freeman and Company, New York. Pauling L. (1991) Case report: Lysine/ascorbate-related amelioration of angina Pauling L (1986):

pectoris. Journal of

Orthomolecular Medicine

6:

144-146.

JK (1992) Neurological disorders and heart disease, p.1810-1826. In: Braunwald E (editor): Heart Disease - A Textbook of Cardiovascular Medicine. WB Saunders Company, Philadelphia. Pfleger R and Scholl F. (1937) Diabetes und vitamin C. Wiener Archiv fur Innere Perloff

Medizin31: 219-230.

Phang JM and Scriver CR. (1989) Disorders of proline and hydroxyproline metabolism, p. 577-597 In: The Metabolic Basis of Inherited Diseases. McGraw Hill, New York, St. Louis, San Francisco. Pyeritz RE. (1992) Genetics and cardiovascular disease, p.1 622-1 655. In: Braunwald E (editor): Heart Disease A Textbook of Cardiovascular Medicine. WB Saunders Company, Philadelphia. -

Ramirez

and Flowers NC. (1980) Leukocyte ascorbic acid and its relationship in man. American Journal of Clinical Nutrition 33: 2079-2087.

to

J

coronary artery disease

Rath M, Niendorf A, Reblin

T, Dietel

M, Krebber H-J. and Beisiegel U.

Detection and quantification of lipoprotein(a)

coronary bypass patients. Arteriosclerosis

Rath

M

and Pauling

L.

Hypothesis:

(1990a)

ascorbate. Proceedings of the National

9:

(1989)

the arterial wall of 107

in

579-592.

Lipoprotein(a)

Academy

of

is

Sciences

a surrogate for

USA

87: 6204-

6207. Rath

M

and Pauling L (1990b) Immunological evidence for the accumulation of in the atherosclerotic lesion of the hypoascorbemic guinea pig.

lipoprotein(a)

Proceedings Rath

M

disease: of

Its

L.

primary cause

lipoprotein(a)

and

M

and Pauling

L.

of

Sciences

is

6:

in

cardiovascular

to the

the vascular wall.

deposition

Journal of

125-134.

(1991b) Apoprotein(a) 6:

87: 9388-9390.

human

ascorbate deficiency, leading

fibrinogen/fibrin

Orthomolecular Medicine

USA

Solution to the puzzle of

(1991a)

Orthomolecular Medicine Rath

Academy

of the National

and Pauling

139-143.

is

an adhesive

protein.

Journal of

188 Rath, M., Pauling,

mortality.

Rath

M

A

(1992a)

L.

way

leading the

and Pauling

L.

and

Orthomolecular Medicine

M.

(1992c)

7:

synthetic

7:

Rath M. (1992d) Solution

7:

Rath M. (1992e) Reducing the supplements. Journal

of

role of

analogs.

Journal

of

ascorbate.

Journal

of

lysine

reduction

by

81-82.

human

the puzzle of

to

Orthomolecular Medicine

human

17-23.

Lipoprotein-a

Orthomolecular Medicine

for

5-15.

7:

Plasmin-induced proteolysis and the

(1992b)

lysine,

cardiovascular disease

disease as a cause

Journal of Orthomolecular Medicine

apoprotein(a),

Rath

human

unified theory of

to the abolition of this

Journal of

evolution.

73-80. risk for

cardiovascular disease with nutritional

Orthomolecular Medicine

7:

153-162.

Cationic-anionic and anionic-cationic oligopeptides

Rath M. (1992f)

in

apoprotein-a and other proteins as modulators of protein action and of biological

communication. Journal

Rath M. (1993) Discovery the

way

of

human

mortality.

Shug AL, and Fleck

Regitz V,

of Applied Nutrition 44:

new elements

metabolism

in

62-69.

communication leading

of biological

to the abolition of infectious diseases, cancer,

as causes

and

of

and other diseases

Journal of Orthomolecular Medicine E.

8:

1

1-20.

Defective myocardial carnitine

(1990)

congestive heart failure secondary to dilated cardiomyopathy

to coronary,

hypertensive and valvular heart diseases.

American

Journal of Cardiology 65: 755-760.

Rhoads GG, Dahlen G. Berg

K,

Morton

NE and Dannenberg

AL. (1986)

Lipoprotein as a risk factor for myocardial infarction.

Lp(a)

Journal of the

American Medical Association 256: 2540-2544.

Riemersma RA, Wood DA, Macintyre CCA, (1991)

Elton RA,

Gey KF and

Oliver

MF.

Risk of angina pectoris and plasma concentrations of vitamins A, C,

and E and carotene. The Lancet 337:

1-5.

Rimm EB, Stampfer MJ, Ascherio AA, Giovannucci E, Colditz GA, and Willett WC. (1993) Vitamin E consumption and the risk of coronary heart disease in men. New England Journal of Medicine 328: 1450-1449. Rivers JM.

Oral contraceptives and ascorbic acid. American Journal of

(1975)

28: 550-554.

Clinical Nutrition

Rizzon P, Biasco G, Di Biase M, Boscia

F,

Rizzo U, Minafra

F,

Bortone A,

and Corsi M. (1989) High doses of Lmetabolic and antiarrhythmic carnitine in acute myocardial infarction: effects. European Heart Journal 10: 502-508. Rose WC, Johnson JE and Haines W. (1950) The amino acid requirement of man. Silprandi N, Procopio A, Bagiella E

Journal of Biological Chemistry 182: 541-556.

Ross

R.

(1993)

The pathogenesis

of atherosclerosis:

a perspective for the

1990s. Nature 362: 801-846.

Salonen JT, Salonen

and Rauramaa

R, lhanainen M, Parviainen M,

R. (1987) Vitamin

C

Seppanen

R,

Seppanen K

deficiency and low linolenate intake

associated with elevated blood pressure: The Kuopio Ischemic Heart Disease Risk Factor Study. Journal of Hypertension 5 (Supplement 5): S521-

S524.

189

Salonen JT, Salonen R, Seppanen K, Rinta-Kiika S, Kuukka M, Korpela H, Alfthan G, Kantola M, and Schalch W. (1991) Effects of antioxidant supplementation on platelet function: a randomized pair-matched, placebocontrolled, double-blind

in

trial

men

with low antioxidant status.

American

Journal of Clinical Nutrition 53: 1222-1229.

Sauberlich

HE and

Machlin LJ (editors). (1992)

on the function and health effects

Academy of Sciences 669. Scanu M, Lawn RM and Berg Annals

of Internal

Beyond

of vitamins.

new views

deficiency:

Annals

New

of the

York

and atherosclerosis.

K. (1991) Lipoprotein(a)

Medicine 115: 209-21 8.

Seed BM, Hoppichler F, Reaveley D, McCarthy S, Thompson GR, Boerwinkle E, and Utermann G. (1990) Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial

New

hypercholesterolemia.

England Journal

of

Medicine 322: 1494-

1499.

Sherry S and

Ralli

metabolism

Simon JA

.

EP.

Further studies of the effects of insulin on the

(1947)

of vitamin C. Journal of Clinical Investigation 27:

C and

(1992) Vitamin

217.

cardiovascular disease: a review. Journal of

11:1 07-1 25. Serum levels of vitamin C

the American College of Nutrition

Smith JL. and Hodges

RE

(1987)

and supplemental intake JJ, Rivers of the

Smith

of vitamin

JM, Machlin LJ

New

York Academy

HA and Jones TC

C

(editors): Third of

in

relation to dietary

smokers and nonsmokers.

in

in:

Burns

Conference on Vitamin C. Annals

Sciences 498.

(editors).

(1958) Veterinary Pathology. 3rd Edition. Lea

and Febiger, Philadelphia. Sokoloff B, Hori M, Saelhof

CC, Wrzolek

T, Imai T. (1966)

and ascorbic acid metabolism. Journal 14: Spittle

of the

Aging, atherosclerosis

American Gerontology Society

1239-1260.

CR. (1973) Vitamin C and deep-vein thrombosis. The Lancet 7822.

2:

199-

201. Statistical

Bulletin

(1989,1-111)

Continued Progress Against Cardiovascular

Diseases. United States National Center of Health Statistics.

Steinberg D, Parthasarathy S, cholesterol. -

Carew TE, and Witztum

atherogenicity.

New

England Journal

Stepp W, Schroeder H. and Altenburger Klinische Wochenschrift 14 [26]:

Stollerman

GH

JL. (1989)

Beyond

Modifications of low-density lipoprotein that increase of

its

Medicine 320: 915-924.

E. (1935)

Vitamin

C und

Blutzucker.

933-934.

(1992) Rheumatic fever and other rheumatic diseases of the

heart, p.1 721 -1741. In:

Braunwald E

(editor):

Heart Disease

-

A Textbook

of

WB

Saunders Company. Philadelphia. Thomsen JH, Shug AL, Yap VU et al. (1979) Improved pacing tolerance of the ischemic human myocardium after administration of carnitine. American Cardiovascular Medicine.

Journal of Cardiology 43: 300-306. Trieu VN, Zioncheck TF,

Lawn RM, and McConathy WJ (1991)

Interaction of

apolipoprotein(a) with apolipoprotein B-containing lipoproteins. Journal of Biology and Chemistry 226: 5480-5485.

190

Trimmer RW, Lundy CJ. (1948) A Practitioner

PDMV

Turlapaty of

II.

survey

nutrition

in

heart disease.

American

No. 7:448-450.

and Altura BM. (1980) Magnesium deficiency produces spasms

coronary arteries: relationship to etiology of sudden death ischemic heart

disease. Science 208:

198-200.

& Human Serv. Public Health (1989) Vital and Health Statistics.

U.S. Dept. of Health

Control

national health interview survey, 1988.

Service, Centers for Disease

Current estimates for the

National Center for Health Statistics.

Utermann G. (1989) The mysteries of lipoprotein(a). Science 246: 904-910. Manch MD, Ashford CA. (1936) Vitamin C deficiency in Addison's disease. The Lancet X/24: 967-970.

Wilkinson JF,

Willis

GC. (1953) An experimental study

atherosclerosis. Willis

GC,

Light

of the intimal ground substance Canadian Medical Association Journal 71: 17-22.

AW, Gow WS.

(1954) Serial arteriography

in

in

atherosclerosis.

Canadian Medical Association Journal 71 562-568. :

GH

and Braunwald E (1992) Endocrine and nutritional disorders and p. 1827-1 855. In: Braunwald E (editor): Heart Disease - A Textbook of Cardiovascular Medicine. WB Saunders Company, Philadelphia.

Williams

heart disease,

Zenker G, Koeltringer

P,

Bone G, Kiederkorn

K, Pfeiffer

K and Jurgens G. (1986)

Lipoprotein(a) as a Strong Indicator for Cardiovascular Disease. Stroke 17:

942-945.

191

INDEX 164-167,180

Addison's Disease

66,15

Aging

114

Detoxification

Diabetes

104-109,164-167,180

116,166-167

Alzheimer's Disease

164-167,180

Dialysis

Amyloidosis

164-167,180

Diet

114,152,166-167

Diuretic Medication

115,134,166-167

64-1 67, 1 80

Amyotrophic Lateral Sclerosis

1

Angina Pectoris

77-82, 90-91

Antioxidants

28,70

Angioplasty

125-127

Edema

130,133-135

Eradicating Diseases

91,109,143,150,

164-180

Apo(a) (See Lipoprotein(a)) Arrhythmia (See Irregular Heartbeat) Atherosclerotic Deposit Reversal

25,

130

Fatigue

FDA

38-41,76-92

2,7,170

Federal Drug Administration (See FDA)

Ascorbic Acid (See Vitamin C)

86

Fibrin

Free Radicals

Balloon Catheter (See Angioplasty)

Beta Carotene (Provitamin A)

1

8,28,

Gangrene

70-73,121,124,127,128 Birth Control

115,167

Risk

Pill

Blood Circulation (Function)

31

111,123-124,164-167,180

55-57

Guinea Pig Gulonolactone Oxidase

1

111-113,164-167,180

Blood Pressure Stability

1

8,50-52,58-59

85-87

Blood Vessel Teflon'

122-124

Bypass Surgery

HDL

83-84,102

Health Care Costs

1

136-140

Cardiomyopathy

18,78,103,139-140,145,147

Heart Disease Statistics

8-11,131-132

27,128-143

Growth

High Blood Pressure

(See Blood Pressure) 38-40,88-89

Clinton,

42-47,54,99-1 00

Rodham

1

73-1 76

8,78,135-138,145

Collagen

18-21,57-58

Connective Tissue Disorders

Ice

1

155-160

Age

Inherited Disorders

Cobalamin (See Vitamin B12)

Coenzyme Q10

164-167,180

Hypertension (See Blood Pressure)

173

Bill

Clinton, Hillary

High-Density Lipoprotein (See HDL)

Homocystinuria

Cerebral Arteries (See Stroke) Cholesterol

32-35

Heart Function

Carotid Arteries (See Stroke) Cell

1,173-176

36,104,120-121

Heart Attack

Heart Failure

Carnitine

55

111,124

Blood Thinning

Blood Vessel

104

Genetic Risk (See Inherited Disorders)

Glucose (See Sugar)

Bioflavonoids (See Vitamin B2)

Blood Clotting

28,41 ,70-71

110,158-167,180

107-108

Insulin

27.144-150

Irregular Heartbeat

64-1 67, 1 80

34-36

Coronary Artery (Function)

Coronary Angioplasty (See Angioplasty)

Kidney Dialysis (See Kidney Failure

Dialysis)

104

Coronary Bypass Surgery

(See Bypass Surgery) Cystic Fibrosis

1

64-1 67, 1 80

LDL Life

Expectancy

23.41^7.99 66.152.171

192

23-25,38-52,58,

Lipoprotein(a)

Very Low-Density Lipoprotein (See VLDL) Vitamin

Body Pool

Low-Density Lipoprotein (See LDL)

Vitamin

A (See

Lupus Erythematodes

Vitamin B1 (Thiamine)

86-88,97-98,158-159

Lysine

1

64-1 67,1 80

Vitamin

18,78,113,121,124,128,145

Minerals

18,78,113,121,124,128,145

Morbus Cushing

1

Multiple Sclerosis

1

Muscle Cell Growth (See

B2

Vitamin

B3

Vitamin

Niacin (See Vitamin B3)

B5 (Pantothenic

B6

Vitamin

Vitamin

C

Pantothenic Acid (See Vitamin B5)

Production

in

Liver

Vitamin Recommendations

VLDL 18,78,85,90,121,124,127

179

Pyridoxine (See Vitamin B6)

164-167,180

Arthritis

164-167,180

Scleroderma

19-21,155-160

77,130

Shortness of Breath

Smog

28,70

Smoking

28,70,114,152,167

Stress

114,167

Stroke

37,59-60,104

104-109

Sugar Surgery (See Bypass Surgery)

14-15,80-82,

Testimonials

141-143,148-149

Thrombosis (See Blood

9,

1

55

13,79,90

41,99

92

Code

Scurvy

1

18,22,28,

70-73,103,121,124-128,151 59-60,

104-106

Clotting)

Tocopherol (See Vitamin E) Triglycerides

C

Vitamin E (Tocopherol)

Pantethine (See Vitamin B5)

Rheumatoid

20-22,28,

145,151,155-167 Vitamin

Protein

(Ascorbic Acid)

50-60, 64-72,95-102,121128,135,

112

Pharmaceutical Companies

27,78-79,103,

121-128,135,145

See Vitamin B3)

Peripheral Vascular Disease

27,78-79,

27,78-79,103,

(Pyridoxine)

B12 (Cobalamin)

Nicotinic Acid (Identical With Niacin)

Proline

Acid)

121-128,135,145

of Niacin,

Oxide

27,78-79,103,

(Niacin)

103,121-128,135,145 Vitamin

Nitric

27,78-79,103,

121-128,135,145

164-167,180

Niacinamide (Derivative

27,78-79,103,

(Riboflavin)

Cell Growth)

Neurofibromatosis

63

121-128,135,145

64-1 67, 1 80 64-1 67, 1 80

7, 1

121-128,135,145

18,78,85-90,121,124,127

Magnesium

1 1

Beta Carotene)

99,101

White House

World Health Organization

173-176 8-9

193

NOTES

194

NOTES

195

ABOUT THE AUTHOR Rath

Dr.

a leading expert

is

in

cardiovascular

He has

disease and

nutrition.

and

positions at the University of

clinical

held research

Hamburg, Germany, and the German Heart Center

Subsequently, he became

Berlin.

in

Director of Cardiovascular

Linus

Pauling

Medicine

Palo Alto, California.

in

promoting

1992

In

Dr.

Now, a company

Health

nutritional

research

at the

Science and

of

Institute

Rath founded

scientific

Research

as

medicine

through

as

through

well

educational services. Over the years Dr.

Rath's

work has appeared

in

scientific

journals of the American Heart Association, the National in

Academy

of

Sciences as well as

Some

other scientific journals.

scientific discoveries are listed

and 180

of this

of

his

on page 179

book.

ACKNOWLEDGEMENTS The author would encouragement,

like to

thank

their criticism,

and Bernard Murphy (SCORE) are used from publications

in

all

those

and

who have made

their help. Special

this

book possible with

thanks go

to Jeffrey

their

Kamradt

for their help with the publication of this book. Pictures

Virchow's Archives of Pathology (pages 39.40.89) and

from the Proceedings of the National

Academy

of

Sciences (page

56).

196

A DAILY PROGRAM OF ESSENTIAL NUTRIENTS FOR OPTIMUM CARDIOVASCULAR HEALTH VITAMINS Vitamin C Vitamin E (d-Alpha Tocopherol) Vitamin A (Beta-Carotene) Vitamin B-1 (Thiamine) Vitamin B-2 (Riboflavin) Vitamin B-3 Vitamin B-5 (Pantothenate) Vitamin B-6 (Pyridoxine) Vitamin B-1 2 (Cyanocobalamin) Vitamin D Folic Acid Biotin

mg

900 200

-

3,000

-

600

2,500 10 10

-

8,000

65 60 15 30 200 130 100

-

50 60 30 20 10

6

-150mg 200 mg - 90 mg - 60 mg -30mg 6 mg 2,000 meg -100 meg - 50 meg - 20 meg

150 150 50 50 50 50 10 10

mg mg -150mg -150mg -150mg -150mg 30 mg 30 mg

-

-

I.U. I.U.

40 mg 40 mg 200 mg 200 mg 50 mg

-100 meg - 600 I.U. - 400 mg - 300 meg

MINERALS Calcium

Magnesium Potassium Phosphate Zinc

Manganese Copper Selenium

Chromium Molybdenum

2

500 30 15

-

-

OTHER IMPORTANT NUTRIENTS L-Proline

L-Lysine L-Carnitine

L-Arginine L-Cysteine Inositol

Coenzyme Q-10 Pycnogenol

-

500 500

-

first values are my minimum daily recommendations for a healthy person. People and patients with additional needs can adjust accordingly.

The

197

HOW YOU CAN GET MORE INFORMATION

If

you have

difficulties finding

recommended

in

book elsewhere

this

HEALTH NOW can

the nutrients

refer

you

to sources.

If

you or your doctor have

a

laboratory that does the lipoprotein(a) testing

HEALTH NOW can

refer

you

difficulties

identifying

to diagnostic

laboratories performing this test.

You can also order directly through

Dr.

Rath founded

nutritional

additional copies of this

book

HEALTH NOW. HEALTH NOW

to

promote

medicine through scientific research

and through educational services.

Parts of the revenues from the sales of this book are

designated for further clinical studies with nutritional

disease,

supplements

strokes,

HEALTH NOW, 387 Tel:

or

the fight against heart

diabetes and other diseases.

Ivy

California

1-800-624-2442

in

Street,

94102,

San Francisco,

USA

916-939-1007 (from overseas).

BOOKS AVAILABLE FROM HEALTH

NOW

"America's Most Successful Cardiovascular Health Program' currently followed by over 20,000 Americans.

is

CARDIOVASCULAR

This book documents the success of this program in form of testimonial letters from patients with coronary heart disease, high blood pressure, irregular heartbeat, heart failure, diabetes and other cardiovascular conditions.

HEALTH

PROGRAM

"Why Animals

161 pages

Don't Get Heart Attacks- But

brief introduction to the

and

nutrition led

In this

short

$12.95

breakthrough

in

Humans Do"

is

a

cardio-vascular disease

by Dr. Rath.

handbook the reader

finds the

answer

to the

most

medical puzzle of our time: "Why does every second man and women die from a disease that is essentially unknown in the animal world?" striking

2nd

edition,

63 pages

m mmt wranwuT «m

or

$8.95

rew un

ERADICATING HEART DISEASE

Heart Disease" is a detailed documentation medical breakthrough.

"Eradicating

about In

this

several chapters patients with different cardiovascular find specific answers to the question which

conditions

essential nutrients can help to optimize their cardiovascular health.

197 pages

$14.95

Keep Your Cardiovascular Health Up To Date by Ordering Health Now's Cardiovascular Newsletter! JuIWAukusi

IW4

Septembt

O Health Now! Cardiovascular Health \ew\ for

Health

First Patented

Therapy

Reverse Heart Disease Without Angioplasty and Bypass to

Surgery Vitamins

What

C

Now!

Diabetic Patients Should

Know About

Health

Now!

C

Vitamins

Supplementations

Is High Blood Pressure Caused B) Deficiencies In

Essentia] Nutrients?

In Diabetic Patients Decrease of Blood Sugar 1

• Vitamin



ardltirau-ular Health

Vitamin

And Natural A mino Acids

Reverse Atherosclerotic Deposits

• 1. -Proline