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book is not intended as a substitute for the medical advice of a physician. The reader should regularly consult a physician in matters relating to his or her health and particularly in respect to any symptoms that may require diagnosis or medical attention. The author and publisher disclaim responsibility for any adverse effects resulting directly or indirectly from the information contained in this book. This

RSA00002 ISBN# 09679546-2-2

2

Cellular Health Series:

Cancer

Matthias Rath, M.D.

First Edition,

May 2002

Cellular Health Series All rights reserved.

No

part of this

-

Cancer. Copyright 2001 by Matthias Rath, M.D.

Published by

MR

Publishing, Inc., Santa Clara,

book may be used or reproduced

in

CA 95054

any manner whatsoever without

written permission except in the case of brief quotations

embodied

in critical articles

or reviews.

3

"We

will live to

to look

say:

see a time

over our shoulder

two and two makes

when we no like a

longer have

criminal

when we

four."

Bertolt Brecht "Life of Galilee" ,

4

Contents Introduction •

Foreword



The End of



The Fundamental Question of Cellular Health



How



Collagen-Dissolving Cell Systems

Cells

Common Move

Diseases

through the Body

Restructuring of Collagen

in

Healthy People



Protection Against Infections



Ovulation

Degradation of Collagen as a Precondition for the

Spread of Diseases •

Collagen Dissolving

in

Infectious Diseases



Collagen Dissolving

in

Cancer



How

— Metastasis



Collagen Dissolving

in

Chronic Inflammation



Collagen Dissolving

in

Advanced Atherosclerosis

Cancer Spreads

Natural Prevention of Collagen Degradation and the Purpose of Enzyme-Blocking Therapy

Enzyme Block



Lysine as a Natural



The Remarkable Value of Lysine



The Balance between Collagen-Dissolving Enzymes

and Lysine •

Successful Use of

Enzyme Blocks



The Use of Lysine

in



Conventional Cancer Therapy



Cancer

-

No

in

Cancer Therapy

Other Serious Diseases



a

Dead-End

Street

Longer a Death Warrant

5

Principles of Natural Therapies • •

— Key Molecules of Cellular Health Collagen Production — a Key Disease Prevention

Vitamin

C and

Lysine

to

and Control •

Nutritional Supplementation with Proline, Lysine,

and Vitamin C •

How Much Vitamin

C?

Questions and Answers Literature

6

and Sources

—A Tolerance

Test

Introduction

Foreword

The End of

Common

Diseases

The Fundamental Question of Cellular Health

How

Cells

Move Through

the Body

Collagen-Dissolving Cell Systems

Foreword book summarizes the progress

This

of Cellular Health in

the battle against several forms of cancer diseases, fact that

among cancer

heart disease



other serious diseases.

It

and

infectious

substantiates the

—the second-largest plague of mankind

will lose

its

threat. This

book

lists

after

key mecha-

how

cancer cells spread through the body and how this process can be blocked in a natural way, without chemotherapy, radiation therapy, and other dangerous and ineffective approaches used today by conventional medicine. It is not surprising, therefore, that the Cellular Health approach can help in diseases that conventional medicine still considers incurable. nisms, describing

The

foundation of

scientific

mation about 1992, through

this

have been available since

applications

its

my

publications.

From

breakthrough

in

personal a

discovery and the infor-

scientific

historical

Cellular Health

investigations

and

perspective, this scientific in

the fields of cancer and

must be noted as an example of how medical science capable of saving millions of lives is suppressed for the benefit of the pharmaceutical industry and other special-interest groups who make profits from the infectious diseases





existence of diseases.

One method

with which the

pharmaceutical industry tries to secure its worldwide power is to ignore the simple and logical causes of common diseases. By using the Latin language and complicated diagnostic medical terminology, millions of patients have been kept in the dark, handing over

own

bodies and health to the medical pharma-cartel. This suddenly changed with the dis-

the responsibility for their

covery that heart attacks and strokes are nothing else but early stages of the sailors' disease, scurvy, and they are possible to cure with vitamin C and other nutrients. The rationale

behind the origin of heart disease has been explained in my Cellular Health Series book The Heart in a way that can be ,

easily understood.

8

This simple, but important, discovery it

was shaken once

before,

shook the world as

400 years ago.

those days the

In

discovery that the Earth revolved around the Sun instead of the other

power.

In

way around shook our time,

it

is

the foundations of those

the discovery that heart disease

is

a disease, but the result of a chronic vitamin deficiency

in

not

and

thus preventable. Practical implementation of this discovery

undermine

market of questionable pharmaceutical drugs. Furthermore, it removes a smoke screen placed on the origin of such a common disease as heart disease. With the understanding of the causes of diseases, patients today have become responsible citizens who can take their health interests into their own hands. will

a multi-mill ion-dollar

remove the screen that was placed in front of cancer. The knowledge about this disease presented in is so logical and understandable that will soon become The book

will also

it

it

an integral part of health education in schools. New natural cancer therapies will also terminate the lucrative pharmaceutical business of destructive chemotherapeutics. If

keep a

you it

new

find the information in this

to yourself.

Make

use of

it!

I

book

invite

helpful,

you

do not

to help build

health-care system that will finally serve the health

people and not share in the profit-making practices of the pharmaceutical industry. interests of the

Do

this for yourself

and out

of responsibility for your

children's generation!

Yours

truly,

Matthias Rath, M.D.

9

The End of

Common

Diseases

This picture presents the latest available statistics of the

World Health Organization regarding the main causes death

in

of

Europe, the United States, and other industrialized

countries at the end of the twentieth century.

Every year

12

million

people worldwide die of the

and

results of atherosclerosis, heart attacks,

are by far the most

common

These

strokes.

causes of death of our time.

Cellular Medicine has already found an answer to this epi-

demic: atherosclerosis and tion

its

consequences, heart

and stroke are early forms

of scurvy.

knowledge, coronary heart disease

will

infarc-

Based on

be reduced

this

to a

fraction of the current figures over the next decades.

The second-most

common

disease

is

cancer

— malignant

tumors. Coronary disease and cancer together are responsible for over

There

tional

how

of

all

deaths

in

industrialized coun-

Incidences of cancer keep increasing on a global sca-

tries. le.

80 percent

it

is

only one plausible explanation for

medicine does not know the causes spreads. Because of this there

is

no

this:

for

conven-

cancer nor

effective

cancer

therapy available and the disease can keep expanding on a global scale.

The most

common

diseases and causes of death

in

loping countries are infectious diseases, including the

deve-

AIDS

epidemic. These serious infectious diseases can only conti-

nue spreading as they do because knowledge of Cellular Health has been not efficiently used. This book will also provide the solution

10

for the control of these diseases.

Common

Diseases and

Causes of Death -World Health Organization 1997-

Gastrointestinal

Problems

Accidents

Suicides

Lung Diseases

Birth Detects

Heart Attacks, Strokes

Eight out of ten people die of

coronary heart disease or cancer

The Fundamental Question of Cellular Health: Where Does the Problem Originate in a Cell? can be considered from two cellular aspects: the lack of biological fuel needed by the Basically, the origin of disease

cell's

power

plants, the mitochondria, or a failure in the func-

tion of the nucleus, the metabolic control center of the cell. 1

.

Lack of biological

fuel in the

power

plants of the cell (mito-

chondria): Coronary heart disease, for instance,

caused by an in

insufficient

supply to the

is

mainly

cell of biological fuel

the form of vitamins and other cell factors. These nutri-

needed for the conversion of food into cellular energy, which is used by the cell in many metabolic reactions. Another example is heart failure, which is caused by a lack of bio-tuel in the cells of the heart muscle. With low ents are

energy production

the

pumping

function

of

the

heart

muscle becomes impaired, causing shortness of breath and the accumulation of fluids in the body. Generally, the supply

and other bio-energy

of vitamins

fuel will correct the

impaired pumping function of the heart muscle. 2.

Diseases caused

by a problem

in

the

cell's

program: The second largest cause of diseases

an error

in

general

is

the metabolic software of the cell's control

center, the nucleus. Like a

computer's

in

metabolic

normal

computer

functions,

virus that will disrupt a

cells

can

under the

fall

control of a disease program. The most important diseases in

this

group are infectious diseases (such as virus

and cancer. This faulty programming will lead preconditions have been met:

infec-

tions)

to a disease

a)

Programming error causes uncontrolled tion," and at the same time

b)

Programming

only

when two

"cell multiplica-

error causes a "disruption of the organiz-

ation of the surrounding connective tissue,"

which enables

the diseased cells to spread.

The mechanisms diseases and the their progress will

12

that facilitate the possibilities of

be discussed

spread of these aggressive

slowing

down

later in detail.

or stopping

Diseases Originate Inside the Cells Most

common

cause of disease:

Lack of Biological Fuel

A

in

the Cell Power Plant

lack of bio-energy carriers

(vitamins, minerals, trace elements) in

the powerplants of the cell (mitochondria)

Second most common cause of disease: Reprogramming of the cell's control system

Aggressive diseases, such as virus infections and cancer,

can spread by reprogramming the metabolic control system within the cell's nucleus.

13

— How If

we want

we must

to

how disease spreads in the body, way cells move through the body. This is

in

the case of red and white blood cells: they

are just carried along

more

difficult to

the Body

understand

look at the

easy to explain

Move Through

Cells

the blood stream. However,

in

how

imagine

cells

it

is

composing other organs

can move through a body's strong connective

tissue. This

happens every second inside our bodies. In

to

move through

order to

the connective tissue, a cell has

be capable of temporarily dissolving the surrounding

tissue

—the collagen and

elastic fibers- so

through. For this purpose the cells use

All

enzymes

can make

enzymes

and weaken the connective

porarily digest

them.

it

that

fibers

its

way

can tem-

surrounding

are proteins that are produced by the cells

themselves and then secreted.

many enzymes bind

In

order to

become

active,

to other molecules, such as trace ele-

ments, which change their biochemical structure and induce their activity. Cellular migration

that the cell secrete

enzymes

ding collagen. This

why

is

as collagen-dissolving In

that

can dissolve the surroun-

these protein molecules are

known

enzymes.

addition, the cell often needs to secrete activators

molecules that can the

through dense tissue requires

cell,

vitalize

dormant enzymes located outside

enabling them to digest and loosen up the surround-

ing collagen molecules.

For

easy

understanding,

enzymes with

red

details regarding the

can be found of the book.

14

in

circled

we show "choppers".

collagen-dissolving Further

scientific

pathway of enzymatic activation stages

the Question

and Answer chapter

at the

end

Cell

Movements Through Body Tissue

Cell nucleus initiates the production of

enzymes

that dissolve collagen

Production of these in

enzymes

the cell

Secretion of

enzymes

into the

surrounding tissue

Enzyme molecules

making

their

way

through collagen fibers of the tissue

Tissue

around

the cell

is

temporarily dissolved

Cell

can move

through body tissue

Collagen-Dissolving Cell Systems Most that

cells of the

can dissolve connective

takes place ges.

body are capable of producing enzymes

In

systems

in

healthy people this

In

certain biologically defined physiological sta-

disease,

a

tissue.

this

happens when

and

cells

become reprogrammed. Cancer

cellular

cells, for instance,

use these "biological weapons" to multiply inside an organ

and then spread through the

entire

body

and other microorganisms also use

"weapon"

How

to

is

it

(metastasis). Viruses

collagen-dissolving

this

spread an infection to other parts of the body.

—the by protein-digesting enzymes — of

possible that a single disease

destruction of collagen

is

such extraordinary value that diseases? The

body

healthy person for

itself

its

mechanism

it

plays a vital role

uses the

normal functions,

in

enzymatic degradation of the connective the function of the body's

and also

immune

during the monthly female cycle and

in

a

various metabolic For

tissue

instance,

important

is

system, during growth,

the restructuring of the

in

serious

same mechanism

pathways, or to restructure certain organs.

in

in all

in

reproductive organs

pregnancy.

However, our bodies are completely helpless when the

mechanism

that

it

normally uses becomes activated and

abused, such as by invading microbes. As soon as the virus or cancer cell its

own

is

capable of overcoming the body with

collagen-dissolving

weapons, the disease

starts

spreading aggressively.

To explain

this

fundamental principle that distinguishes

our health from disease,

we

this collagen-dissolving

mechanism

physiological functions.

16

will look at

to

how

the

perform

body uses its

normal

Cell Systems that

Dissolving

Use a Collagen

Mechanism

Health (normal metabolism)

White blood

cell

("police cells")

Disease (disrupted metabolism)

Cancer

cell

17

Notes

18

Restructuring of Collagen in

Healthy People



Protection Against Infections



Ovulation

Protection against Infections The body's basic protection against invaders (microbes) secured by the white blood cells ("police

groups of white blood

immune

cells

cells"). Several

perform specific functions

is

sub-

in

the

system. Especially important are the macrophages,

which can "eat" and

digest

Immature forms of

invaders.

these "eating cells," called monocytes, can reach every part

body through the blood stream.

of the

place

in

attract

the lungs, the

monocytes

The police

If

an infection takes

body releases "alarm substances"

that

to the source of microbial invasion.

cells,

arriving

traverse the blood vessel wall

through the blood stream,

and move

into the lung tissue

with the help of collagen-dissolving enzymes. Using this

mechanism

in

the blood capillary wall, the police cells

temporarily create a space between the cells vessel wall (endothelium),

which allows them

in

to

the blood

move from

the blood into the lung tissue.

The eating tissue. to

viruses

cells

reach the

and

must be able

site in

to

move through

the lungs that has been invaded by

bacteria. In order to

do

this,

monocytes use the

same collagen-dissolving mechanism. They gen-dissolving

Thus

cells

sue and that cuts

enzymes

the lung

in

secrete colla-

the direction of the infection.

can loosen the dense connective surrounding

tis-

move through the tissue much like an expedition its way through the jungle with a machete.

The connective

tissue will close again right after the cell

has passed through, using the compensating mechanisms that repair the tissue. This repair

is

assured by the optimal

production of collagen molecules that require a sufficient supply of vitamin

20

C and

other cell factors

in

the diet.

Collagen Dissolving

in

the

Immune System Example: Lung Infection

-

Infection

in

the lung

-

Blood vessel in

the lung

The "police cell" leaves the

blood vessel

The "police cell" moves toward the area of infection with the help

of collagen-dissolving

enzymes

The "police

cell"

engulfs cells that cause

an infection

After "police cells"

have passed through, the tissue repairs itself

Place of infection in

the lung

(bacteria

and other

infectious agents)

"Police cells" destroy enveloped bacteria

Ovulation The ovulation process

the female body.is

in

most fascinating functions

one

of the

which the body continuously

in

uses a collagen-dissolving mechanism. Monthly hormonal

changes

the

in

half of the

the ripening egg cell

amounts of

female cycle stimulate certain

which build the wall around

(granulocytes),

types

cell

first

These

(follicle).

cells

produce

large

enzymes.

fluid rich in collagen-dissolving

the middle of the cycle, the ripened egg contains so

In

much

enzyme

collagen-dissolving

that

it

is

capable of

temporarily dissolving the collagen tissue of the ovarian wall. This

mechanism operates every month, allowing the

move from

egg

cell to

and

into the

It

is

womb

the ovary through the fallopian tube

(uterus).

mechanism needs

clear that this

to

be precisely

timed and to be confined to a specific location. This mecha-

nism must

let

only one egg per cycle ripen and pass

through. Therefore, dissolving

it

is

absolutely necessary that collagen-

enzymes remain

in

and physiological

a timely

balance with the mechanism that blocks these enzymes and initiates self-healing of the tissue.

Immediately

after the

egg

activity of collagen-dissolving

body's

own enzymatic

cell

has

left

enzymes

is

the ovary, the

stopped by the

blocks. This shifts the balance toward

collagen-producing mechanisms, which dominate over the collagen-dissolving

process.

tissue of the ovary wall

Four weeks

later,

22

menopause.

this

mechanism the

can quickly heal and close

itself.

during the next cycle, the whole process

repeats, taking place in the until

Using

body

of every healthy

woman

Collagen Dissolving During Ovulation

Womb

Fallopian tube

(Uterus)

Ovary

1

.

First

enlargement

(view inside the ovary):

Ripening egg

cell shortly

before ovulation

Ovulation: Ripe egg passes through the ovary wall

and enters the tube

2. Second enlargement

(view inside follicle cell):

Ri|X‘ning egg cell

surrounded by

follicle

cells prrxlucing collagen-

dissolving

enzymes

Ovulation

Temporary enlargement:

egg

cell

can leave

the ovary

maximum

collagen-dissolving

production of

enzymes "opens"

the tissue for a few seconds

23

Notes

24

Degradation of Collagen Is

a Precondition for

the Spread of Diseases

Collagen Dissolving

Collagen Dissolving

How

in Infectious

in

Cancer Spreads

Diseases

Cancer

— Metastasis

Collagen Dissolving

in

Chronic Inflammation

Collagen Dissolving

in

Advanced Atherosclerosis

Collagen Dissolving

Infectious Diseases

in

The collagen-dissolving mechanism plays an especially important role

infectious diseases.

in

Without dissolving

the surrounding connective tissue, the agents that cause

diseases (viruses,

cannot invade the body and

bacteria)

spread the disease. The illustration on the next page shows

how

mechanism

this

is

used

the development of an

in

influenza infection.

Unlike software

all

the nucleus) and hardware (production system

(in

for protein

other cells, which contain both metabolic

and other metabolic molecules),

a virus consists

only of software (genetic information). To reproduce plies inside a host cell using, the host's cell

case of a

flu virus,

membrane

in

it

multi-

hardware.

the host cell can be a cell of the

In

the

mucous

the nose, throat, or lungs. As soon as the virus

has invaded the host

cell,

it

incorporates

its

genetic informa-

tion into the nucleus of the host. This allows the virus to

convert metabolic functions of the host

cell

for

its

own

purposes and spread the infection through: 1.

Multiplication of the virus. The metabolic production

system of the host

cell receives

an order to multiply the

virus particles. After multiple reproduction cycles, virus particles are released

by the host

ding area, where the newly

new 2.

made

surroun-

viruses can invade

cells.

Mass production

of collagen-dissolving

virus also orders the host cell to

ving enzymes. The host

which

start to

The more

produce collagen-dissolexcretes these enzymes,

dissolve the surrounding tissue. The infec-

a virus

is

capable of using the metabolism of a

two purposes, the faster a virus spread and the sicker a patient will feel.

host cell for these tion will

cell

enzymes. The

can easily spread to other parts of the body.

tion then

26

cell into the

infec-

Collagen Dissolving in

Virus Infections

(e.g.,

the Flu)

Virus particle

Virus's genetic information

(e.g., flu virus)

(metabolic software)

Host

cell

mucous membrane cell)

(e.g.,

Virus transfers its

software

to the nucleus

of the host

Metabolic software of the host cell

reprogrammed

is

1

.

First

Host

cell

change: begins a

mass production of the virus

2.

Second change:

Host cell begins production of collagen-dissolving

enzymes

Collagen-dissolving

Infection spreads

through the body

open the way

enzymes

for virus

particles

27

Collagen Dissolving

in

Cancer

forms of cancer spread with the help of the collagen

All

dissolving mechanism. This illustration

shows an example

of

the development of liver cancer.

The

liver

is

the body's central metabolic organ, and

it

is

responsible for neutralizing and removing toxins from the

body. Toxins such as pesticides and preservatives entering the

body from the cancer. Also, in

the

all

diet,

are the most

common

cause of

pharmaceutical drugs have to be detoxified

liver. In this

context,

January 1996, the Journal of the

in

American Medical Association (JAMA) issued all

cholesterol-lowering medications

were carcinogenic (cancer

that time

liver

Liver cells that are

exposed

(statins)

a

warning

that

on the market

at

causing).

to these

poisonous substances

can be destroyed or permanently damaged. This damage often involves an error in the genetic (cell's

program of the

software), similar to

what we have seen

damage can

two processes

tions. This

trigger

cells

in virus infec-

that facilitate the

development of cancer: 1

.

Uncontrolled cell

cell multiplication.

reprogrammed

is

in

such

The software of a

way

that

constant reproduction and multiplication of the

uncontrolled cellular multiplication tion for 2.

is

the

first

a cancer it

causes

cell.

This

precondi-

cancer to develop.

Mass production

of collagen-dissolving

second precondition

enzymes. The

enzymes that destroy the surrounding connective tissue that would is

the production of

otherwise keep the cancer cells confined.

Research has established that the more enzymes a cancer cell

produces, the more aggressively the cancer develops. The

faster the life

28

cancer can spread through a body, the shorter the

expectancy of the patient

if

the

mechanism

is

not stopped.

Collagen Dissolving -

Local

Growth

in

Cancer

of Cancer

-

Liver cells: Liver

*

*

Healthy

Cancer

cells

(brown)

cells (green)

Liver cell

enlarged

Software of a liver cell

reprogrammed be a cancer

to

cell.

This means:

1

.

Characteristic of cancer:

Uncontrolled cell

2.

multiplication

Characteristic

of cancer:

Mass production of collagen-dissolving

enzymes

Liver cells break through the surrounding tissue

spread to form a

liver

and

tumor

29

— How

Cancer Spreads (Metastasis)

The collagen-dissolving mechanism also plays role in the spread of

tumors

in

a

major

cancer and the growth of secondary

other organs or parts of the body (metastasis). The

shows the metastasis

illustration

of a liver tumor.

Small blood vessels provide oxygen and nutrients to

tumor

The walls of these blood

cells.

capillaries are not

obstacles for a cancer cell. With the help of collagen-dissol-

ving enzymes, a cancer cell can "eat" of the small blood vessel

and

its

way

lumen

blood stream. The

into the

blood can then carry away cancer

into the

by which they can

cells,

spread and invade other organs. In this

example, the obstacles

for the

cancer

cell in

the

blood stream are small lung capillaries that supply oxygen to the blood.

than a

hair,

The diameter of these

so the cancer cell attaches

the capillary and "eats"

its

dissolving enzymes. This tissue.

In

capillaries

way way

in

itself

is

smaller

to the wall of

with the help of collagen-

the cell can enter the lung

the lung, the cancer cell starts to multiply and

develop into a secondary tumor, the metastasis. The same kind of tumor inside the lung as the original one

The same

rule applies to the

in

the

liver.

development of secondary

tumors: the more collagen-dissolving enzymes a specific

cancer

cell

develop

can produce, the

— not only

and the more

30

in

faster

secondary tumors

the lungs but also

ilia patient will

become.

in

will

other organs

Collagen Dissolving

in

m

Cancer

Cancer Spreading Through the Body

Liver

Cancer

tumor

cell

leaving the liver

Blood vessel the liver

in

First

Step

of metastasis:

Cancer

cells enter the

blood stream with the help of enzymes

Through the blood stream cancer cells reach other organs

Second step of metastasis: Cancer

cells leave

(he blood stream

using collagen dissolving

enzymes

Lung metastasis: Tumor cells from the liver now grow and spread in the lung

MM 31

Collagen Dissolving Chronic Inflammation

in

enzymes

Collagen-dissolving

also play a crucial part in the

spread of other diseases. The picture shows an example of a long-term inflammation of the knee joint (chronic

The body's defense inflammation.

belong

Because of

cells play a crucial role in fighting

As you

already

know,

cells

defense

cells

(leukocytes).

their function, these cells are often called the

"police cells." Especially important le

the

group of white blood

the

to

arthritis).

against "foreign" substances

in this

and also

in

group

in

the batt-

the "clearance of

the inflammation battlefield" are the so-called "eating-cells"

(macrophages).

What happens

if

an inflammation continues

time because the invaders' attack

body engages too many

of

its

is

long

for a

too powerful and the

police cells? The result

is

that

the eating cells secrete high quantities of their "defense

substances" over a long period of time. This defense consists not only of collagen-dissolving a load of free radicals.

As

we saw

in

the

enzymes but example

move through

infection.

If

the

also of

of the lung

infection, the police cells use collagen-dissolving to

weapon

enzymes

thick connective tissue to get to the area of

immune

system's battle on the site of the

inflammation takes too long, then huge amounts of collagen-dissolving

enzymes

are secreted, creating a problem:

inflammation will erode the surrounding connective

the

tissue

and turn

into a chronic (long-term) process.

Chronic inflammations are not simply joints but ever,

can also be found

organs of the body.

How-

independent of the organ where the inflammation

takes place, the

body

and mechanisms.

32

in all

bone

restricted to

will

always use the same defense

cells

Collagen Dissolving

in

Chronic Inflammation -

e.g.,

Knee

Inflammation of the Joint

(Arthritis)

Inflammation

joint

in

-

the

joint cavity

"Police cells" try to fight the

inflammation

Enlargement:

The "police cells" are abundant long-term inflammation in

Activated "police cells" secrete large quantities of

% $

enzymes, destroying the connective tissue

Over-secretion of collagen-dissolving enzymes contributes to the continuation of the disease.

An acute inflammation becomes

a chronic one.

33

Collagen Dissolving in

Advanced Atherosclerosis

During the growth of atherosclerotic plaques

even

in

(deposits),

advanced stages of atherosclerosis, the collagen

dis-

solving process plays an important role. It

vy,

generally

is

the

initial

known

step

in

that, as in

the sailors' disease, scur-

the development of atherosclerosis

As

lack of vitamins in the arterial wall.

min deficiency the process

repair

arteries of the heart

to

vessels. Initially, the teins)

and other

them

in

stabilize

body mobilizes

a

a result of this vita-

weaken, triggering

wall

the

is

of

a

blood

these

fatty particles (lipopro-

repair molecules from the

blood to deposit

the weakest areas of the arterial wall.

When

these repair measures

weakening

arterial

wall

is

become inadequate stabilized

further

the

through an

uncontrolled growth of the cells that build the vascular wall.

These

cells,

outermost

called smooth-muscle cells, migrate from the

cell

layer of the artery to the area that contains

atherosclerotic fatty deposits. These muscle cells have to

move through

a very strong

and dense intermediate

collagen fibers and connective tissue In

layer of

—the basal membrane.

order to do that, smooth-muscle cells produce collagen-

dissolving

enzymes

that

them pass through the

can loosen the collagen and

basal

membrane and move

in

let

the

direction of the plaque.

The

effective natural

approach

to the prevention

and

treatment of atherosclerosis preserves the integrity of the artery walls, through an optimal supply of vitamins. In

the next part of this

book we

will discuss the

mecha-

nisms that can block the disintegration of collagen natural way.

34

in

a

Collagen Dissolving

in

Advanced Atherosclerosis

Cross-section of an artery

Atherosclerotic deposits

Enlargement:

View

inside

the deposit

Dead center of the dejx)sit (with cellular waste)

Muscle

of the

cell layer

artery wall

Intermediate

between inner and outer layer

arterial wall

(basal

membrane)

Smooth muscle through

cells

move

arterial wall

to stabilize the

deposits

Collagen dissolving

enzymes "open up" a basal

membrane

Uncontrolled growth of smooth muscle cells contributes to atherosclerosis and clogging of the artery

35

Notes

36

Natural Prevention of Collagen Degradation

and Enzyme-Blocking Therapy

Enzyme Block



Lysine as a Natural



The Remarkable Value of Lysine



The Balance between Collagen-Dissolving Enzymes

and Lysine

Enzyme Blocks



Successful Use of



The Use of Lysine



Conventional Cancer Therapy



Cancer

in

in

Cancer Therapy

Other Serious Diseases

— No Longer

a



a

Dead-End

Street

Death Warrant

37

Lysine as a Natural

In

we

previous chapters

collagen dissolving

Enzyme Block

have learned about the role of

facilitating

in

through the body. The activation of

mechanism

leads to the

the spread of diseases

collagen-dissolving

this

development

of aggressive diseases

such as cancer and microbial infections. Apart from

mechanism

plays

an

important role

progress to advanced stages. that will halt this

fore

mechanism

all

diseases that

Every therapeutic possibility

or even slow

be a momentous success

Nature

in

that, this

in

it

down

will there-

the field of medicine.

provides us with two large groups of mole-

itself

cules that can block the collagen-dissolving mechanism.

The

first

group

is

the body's intrinsic enzymatic block that

can stop the action of collagen-dissolving enzymes

moments. The second group stances that

come from

The most important one acid L-lysine.

When

is

a

few

the enzyme-blocking sub-

our diet or as dietary supplement. in this

a sufficient

as a dietary supplement,

in

it

group

is

amount

the natural

of lysine

can block the anchor

is

amino

supplied

sites in

the

connective tissue that collagen-dissolving enzymes use to attach themselves to the tissue. Lysine, thus prevents these

enzymes from uncontrollably This

is

illustrated

produce high

dissolving connective tissue.

on the next page: while the

levels of collagen-dissolving

cells

enzymes,

in

still

the

presence of lysine these enzymes are no longer breaking

down

collagen.

Therefore,

uncontrolled

degredation

of

collagen and connective-tissue structure can be prevented.

The spread of diseases can be slowed or stopped.

38

Lysine

Is

the

Natural

Most

Way

Effective

to Block

Collagen-Dissolving Enzymes

Lysine, the natural

enzyme block

must be supplied from the

diet

Lysine occupies the areas

where enzymes bind to the tissue (anchor sites) and blocks their effects

Collagen-dissolving

enzyme

Prevention of uncontrolled collagen degredation

39

The Remarkable Value of Lysine

by biological language.

human body are controlled Some twenty known amino acids

compose

in

metabolic functions

All

of

life

the proteins

all

function like the

words

amino acids The

of the alphabet.

amino acids

(peptides)

lysine

to create

and sentences

innumerable

(proteins). Separate

a prime example.

is

body can produce most amino acids

cells of the

amino acids

themselves. These

Our bodies use

also have important individual metabolic

(letters)

and

functions,

our bodies. These building blocks

letters

various combinations of biological

the

in

are

called

However, there are nine known amino acids cannot produce, they have

to

These amino acids are called

nonessential.

body

that our

be supplied through the

diet.

essential.

Lysine plays a similarly important role within the group of essential

amino acids

as vitamin

C does

within the vitamin

group. The daily requirement for lysine surpasses that of other

amino

Among

acids.

its

the basic building block of the

many

amino acid

important for energy metabolism

The this

fact that the

amino acid

health.

functions, lysine

in

every

human body can

its

also

is

which

is

cell.

store a large

proof enough of

is

carnitine,

all

amount

importance

for

of

our

About 25 percent of collagen, the most abundant and

important structural molecule of bones, skin, blood vessel walls, lysine

and

and

all

other organs, consists of two

proline.

acids,

As the summary on the next page shows,

70

a person weighing

amino

of lysine stored in the

kg.

(1

body

55

lbs.)

has about 500

g. (1

.1

lbs.)

at all times.

Taking large quantities of lysine will not cause adverse

Our metabolism

effects.

amounts

of lysine,

and

it

is

will

familiar

40

all

people

suffer

handling

large

simply excrete the molecules

that are not used. Rather, the opposite

Almost

with

is

generally the case:

from a chronic deficiency of

lysine.

Lysine

1

Molecule

nm

=

— Made by Nature

Millionth of a Millimeter

1

(10,000 times smaller than a

How much •



can our bodies handle?

lysine

A human body tains

about 22

50%

of this

cell)

weighing about 155

lbs.

lbs.

con-

of proteins.

mass

protein

is

present

as

the

connective tissue proteins, collagen and elastin •

The amino acid lysine forms about

1

2 percent of

the collagen and elastin mass, or about to •

1

1

.1

lbs.

.3 lbs.

A human body tains

weighing

approximately

1

.1

1

55

lbs.

lbs.

therefore con-

of lysine.

Since our bodies are accustomed to such large

amounts

of lysine, taking

0g of lysine daily as a dietary supplement should not be considered as 1

excessive.

41

The Balance between CollagenDissolving Enzymes and Lysine

We

have already learned that enzyme

own molecules and

blocked with the body's supplied through the

such as

diet,

block (enzymatic inhibitor) assures the balance

them

check.

in

In

the

the

line of

defense that

the body's systems and keeps

illustration, is

with those

The body's own

lysine. first

can be

the

enzyme block

represented by green arrows.

molecules have the same function, but are the

Lysine

second

own

is

among

produced by the body

activity

line of defense,

ready to step

in

when

the body's

systems are insufficient. The lysine block cannot over-

shoot

its

goal,

A second

even when taken important fact

in

amounts, as high as

shown

in

the illustration

1

is

balance between the collagen-dissolving mechanism

and

g.

the

(red)

blocking mechanism (green) during sickness and

its

health. In

balance.

normal conditions these systems are

When

in

perfect

"police cells" are wandering through the

body, the balance

is

disturbed. But the healthy

restores the balance within In

0

body then

moments.

cancer and other previously described diseases,

balance becomes disrupted

in

this

favor of the collagen-dissol-

ving mechanism. Because the natural cellular mechanisms

cannot

sufficiently block the collagen-dissolving process, a

high-dosage dietary supplement of lysine ble therapy to stop or to slow this

therapy

is

down

is

the only possi-

this process.

to correct the disrupted

The goal of

balance with a long-

term high concentration of lysine to block disintegration of collagen.

42

Collagen-Dissolving Enzymes

and Their Blocks in

Disease and Health Block (produced by the body)

Collagen Dissolving

Enzyme

^

Block from the diet (Lysine)

1

ic

*

oo

Health:

Balance or

{& fc

/c cc ccc

oo *

oo

Temporary Imbalance

Immediately Restored

Disease:

v